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Chemical Compound Review

Isocarbacyclin     5-[5-hydroxy-6-[(E)-3- hydroxyoct-1-enyl]-1...

Synonyms: TEI-7165, AC1O5PME, Tei 7165, LS-101457, LS-178442, ...
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Disease relevance of Tei 7165


High impact information on Tei 7165


Biological context of Tei 7165


Anatomical context of Tei 7165


Associations of Tei 7165 with other chemical compounds


Gene context of Tei 7165


Analytical, diagnostic and therapeutic context of Tei 7165


  1. Effects of the isocarbacyclin methyl ester clinprost incorporated into lipid microspheres, in focal ischemia of stroke-prone spontaneously hypertensive rats. Yae, T., Araki, H., O-ogami, Y., Iwasaki, K., Tanabe, H., Fujiwara, M. Arzneimittel-Forschung. (1997) [Pubmed]
  2. A novel subtype of the prostacyclin receptor expressed in the central nervous system. Takechi, H., Matsumura, K., Watanabe, Y., Kato, K., Noyori, R., Suzuki, M., Watanabe, Y. J. Biol. Chem. (1996) [Pubmed]
  3. Species differences in hydrolysis of isocarbacyclin methyl ester (TEI-9090) by blood esterases. Minagawa, T., Kohno, Y., Suwa, T., Tsuji, A. Biochem. Pharmacol. (1995) [Pubmed]
  4. Development of pressurized retinal resistance-sized arteriolar preparation with special reference to acetylcholine-induced nitric-oxide-mediated vasodilatation. Kazama, A., Ikomi, F., Yashiro, Y., Ohhashi, T. Jpn. J. Physiol. (2002) [Pubmed]
  5. Relaxant actions of nonprostanoid prostacyclin mimetics on human pulmonary artery. Jones, R.L., Qian, Y.M., Wise, H., Wong, H.N., Lam, W.L., Chan, H.W., Yim, A.P., Ho, J.K. J. Cardiovasc. Pharmacol. (1997) [Pubmed]
  6. Neuroprotective effect of TTC-909, an isocarbacyclin methyl ester incorporated in lipid microspheres, on hippocampal delayed neuronal death of stroke-prone spontaneously hypertensive rats. Yamashita, K., Kataoka, Y., Nakashima, M.N., Yamashita, Y.S., Tanabe, H., Araki, H., Niwa, M., Taniyama, K. Jpn. J. Pharmacol. (1996) [Pubmed]
  7. A preliminary double-blind cross-over trial of lipo-PGI2, a prostacyclin derivative incorporated in lipid microspheres, in cerebral infarction. Hoshi, K., Mizushima, Y. Prostaglandins (1990) [Pubmed]
  8. Determination of protein binding of a highly lipophilic drug, isocarbacyclin methyl ester (TEI-9090), using a polydimethylsiloxane-coated glass beads assay. Minagawa, T., Kohno, Y., Suwa, T., Tsuji, A. J. Pharm. Pharmacol. (1994) [Pubmed]
  9. Vasorelaxant effect of isocarbacyclin methyl ester incorporated into lipid microspheres on isolated canine arteries. Sawada, K., Aoki, K., Katsuura, Y., Tanabe, H., Kiyoki, M., Araki, H. Arzneimittel-Forschung. (1995) [Pubmed]
  10. TEI-3356, a highly selective agonist for the prostaglandin EP3 receptor. Negishi, M., Harazono, A., Sugimoto, Y., Hazato, A., Kurozumi, S., Ichikawa, A. Prostaglandins (1994) [Pubmed]
  11. Marked enhancement in antithrombotic activity of isocarbacyclin following its incorporation into lipid microspheres. Mizushima, Y., Igarashi, R., Hoshi, K., Sim, A.K., Cleland, M.E., Hayashi, H., Goto, J. Prostaglandins (1987) [Pubmed]
  12. Effect of isocarbacyclin methyl ester incorporated in lipid microspheres on experimental models of peripheral obstructive disease. Murakami, T., Sawada, K., Taneda, K., Hayashi, M., Katsuura, Y., Tanabe, H., Kiyoki, M., Araki, H. Arzneimittel-Forschung. (1995) [Pubmed]
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