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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Drug Compounding

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Disease relevance of Drug Compounding


High impact information on Drug Compounding


Chemical compound and disease context of Drug Compounding


Biological context of Drug Compounding


Anatomical context of Drug Compounding


Associations of Drug Compounding with chemical compounds

  • Nitrofurantoin showed little anti-P. carinii activity despite different doses or drug preparations [26].
  • In this study, we examined the glycemia and insulin secretion in streptozotocin-diabetic rats transplanted with islets subjected to immunoisolation with Algire diffusion chamber or with microencapsulation [27].
  • CONCLUSIONS: Microencapsulation using the present alginate/poly-L-lysine/alginate capsules does not protect islets against the detrimental effects of IL-1beta and TNF-alpha [28].
  • The method was applicable to the qualitative and quantitative analysis of prostaglandin E1 in a drug preparation [29].
  • The immunogenicity of formalin-treated influenza vaccine was preserved during the microencapsulation process, and the microencapsulated antigen induced protective immune responses after systemic immunization that were equal to or higher than those induced by conventional vaccine [30].

Gene context of Drug Compounding


Analytical, diagnostic and therapeutic context of Drug Compounding


  1. In vivo administration of vascular endothelial growth factor (VEGF) and its antagonist, soluble neuropilin-1, predicts a role of VEGF in the progression of acute myeloid leukemia in vivo. Schuch, G., Machluf, M., Bartsch, G., Nomi, M., Richard, H., Atala, A., Soker, S. Blood (2002) [Pubmed]
  2. Comparative pharmacokinetic studies of three asparaginase preparations. Asselin, B.L., Whitin, J.C., Coppola, D.J., Rupp, I.P., Sallan, S.E., Cohen, H.J. J. Clin. Oncol. (1993) [Pubmed]
  3. 4-chloro-m-cresol triggers malignant hyperthermia in susceptible swine at doses greatly exceeding those found in drug preparations. Iaizzo, P.A., Johnson, B.A., Nagao, K., Gallagher, W.J. Anesthesiology (1999) [Pubmed]
  4. Effect of microencapsulation on immunogenicity of a bovine herpes virus glycoprotein and inactivated influenza virus in mice. Moser, C.A., Speaker, T.J., Offit, P.A. Vaccine (1997) [Pubmed]
  5. Use of traditional African fermented beverages as delivery vehicles for Bifidobacterium lactis DSM 10140. McMaster, L.D., Kokott, S.A., Reid, S.J., Abratt, V.R. Int. J. Food Microbiol. (2005) [Pubmed]
  6. Synthesis and evaluation of a prototypal artificial red cell. Hunt, C.A., Burnette, R.R., MacGregor, R.D., Strubbe, A.E., Lau, D.T., Taylor, N., Kiwada, H. Science (1985) [Pubmed]
  7. An engineered epigenetic transgene switch in mammalian cells. Kramer, B.P., Viretta, A.U., Daoud-El-Baba, M., Aubel, D., Weber, W., Fussenegger, M. Nat. Biotechnol. (2004) [Pubmed]
  8. Effect of alginate-polylysine-alginate microencapsulation on in vitro insulin release from rat pancreatic islets. Fritschy, W.M., Wolters, G.H., van Schilfgaarde, R. Diabetes (1991) [Pubmed]
  9. Low-dose oral recombinant interferon-alpha A in patients with HIV-1 infection: a blinded pilot study. Sperber, S.J., Gocke, D.J., Haberzettl, C.A., Pestka, S. AIDS (1993) [Pubmed]
  10. Topical benzoic acid induces the increased biosynthesis of prostaglandin D2 in human skin in vivo. Downard, C.D., Roberts, L.J., Morrow, J.D. Clin. Pharmacol. Ther. (1995) [Pubmed]
  11. 4-chloro-m-cresol is a trigger of malignant hyperthermia in susceptible swine. Wappler, F., Scholz, J., Fiege, M., Kolodzie, K., Kudlik, C., Weisshorn, R., Schulte am Esch, J. Anesthesiology (1999) [Pubmed]
  12. Microencapsulation of Aerococcus viridans with catalase and its application for the synthesis of dihydroxyacetone phosphate. Streitenberger, S.A., Villaverde, M.J., Sánchez-Ferrer, A., García-Carmona, F. Appl. Microbiol. Biotechnol. (2002) [Pubmed]
  13. Parenteral transmission of HIV among injection drug users: assessing the frequency of multiperson use of needles, syringes, cookers, cotton, and water. McCoy, C.B., Metsch, L.R., Chitwood, D.D., Shapshak, P., Comerford, S.T. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. (1998) [Pubmed]
  14. Free and microencapsulated Lactobacillus and effects of metabolic induction on urea removal. Chow, K.M., Liu, Z.C., Prakash, S., Chang, T.M. Artificial cells, blood substitutes, and immobilization biotechnology. (2003) [Pubmed]
  15. Application of microencapsulation for toxicology studies. II. Toxicity of microencapsulated trichloroethylene in Fischer 344 rats. Melnick, R.L., Jameson, C.W., Goehl, T.J., Maronpot, R.R., Collins, B.J., Greenwell, A., Harrington, F.W., Wilson, R.E., Tomaszewski, K.E., Agarwal, D.K. Fundamental and applied toxicology : official journal of the Society of Toxicology. (1987) [Pubmed]
  16. Microencapsulated, CYP2B1-transfected cells activating ifosfamide at the site of the tumor: the magic bullets of the 21st century. Löhr, M., Hummel, F., Faulmann, G., Ringel, J., Saller, R., Hain, J., Günzburg, W.H., Salmons, B. Cancer Chemother. Pharmacol. (2002) [Pubmed]
  17. Measurement of theophylline absorption from different regions of the gastro-intestinal tract using a remote controlled drug delivery device. Staib, A.H., Loew, D., Harder, S., Graul, E.H., Pfab, R. Eur. J. Clin. Pharmacol. (1986) [Pubmed]
  18. Intraocular pressure effects of carbonic anhydrase inhibitors in primary open-angle glaucoma. Lichter, P.R., Musch, D.C., Medzihradsky, F., Standardi, C.L. Am. J. Ophthalmol. (1989) [Pubmed]
  19. Microencapsulation and culture in vitro of rat pinealocytes. Hua, L., Dachuan, X., Lei, Y., Shaohu, X., Xiaojing, L., Tao, H., Shizheng, Z. The International journal of artificial organs. (2003) [Pubmed]
  20. Application of microencapsulation for toxicology studies. I. Principles and stabilization of trichloroethylene in gelatin-sorbitol microcapsules. Melnick, R.L., Jameson, C.W., Goehl, T.J., Kuhn, G.O. Fundamental and applied toxicology : official journal of the Society of Toxicology. (1987) [Pubmed]
  21. Assessment of insulin secretion in vitro from microencapsulated fetal porcine islet-like cell clusters and rat, mouse, and human pancreatic islets. Sandler, S., Andersson, A., Eizirik, D.L., Hellerström, C., Espevik, T., Kulseng, B., Thu, B., Pipeleers, D.G., Skjåk-Braek, G. Transplantation (1997) [Pubmed]
  22. Microencapsulation of Leydig cells: a system for testosterone supplementation. Machluf, M., Orsola, A., Boorjian, S., Kershen, R., Atala, A. Endocrinology (2003) [Pubmed]
  23. Microencapsulation of CHO cells in a hydroxyethyl methacrylate-methyl methacrylate copolymer. Dawson, R.M., Broughton, R.L., Stevenson, W.T., Sefton, M.V. Biomaterials (1987) [Pubmed]
  24. HEMA/MMMA microcapsule implants in hemiparkinsonian rat brain: biocompatibility assessment using [3H]PK11195 as a marker for gliosis. Campioni, E.G., Nobrega, J.N., Sefton, M.V. Biomaterials (1998) [Pubmed]
  25. Dextran sulphates protect porcine arterial endothelial cells from free radical injury. Hiebert, L.M., Liu, J.M. Human & experimental toxicology. (1994) [Pubmed]
  26. Furazolidone and nitrofurantoin in the treatment of experimental Pneumocystis carinii pneumonia. Walzer, P.D., Kim, C.K., Foy, J., Zhang, J.L. Antimicrob. Agents Chemother. (1991) [Pubmed]
  27. Insulin secretion in streptozotocin-diabetic rats transplanted with immunoisolated islets. Ar'Rajab, A., Bengmark, S., Ahrén, B. Transplantation (1991) [Pubmed]
  28. Cytokine-induced functional suppression of microencapsulated rat pancreatic islets in vitro. King, A., Andersson, A., Sandler, S. Transplantation (2000) [Pubmed]
  29. Analysis of leukotrienes, prostaglandins, thromboxane B2 and their metabolites by capillary isotachophoresis. Tsikas, D., Fauler, J., Bracht, S., Brunner, G., Frölich, J.C. Electrophoresis (1993) [Pubmed]
  30. Oral immunization with influenza virus in biodegradable microspheres. Moldoveanu, Z., Novak, M., Huang, W.Q., Gilley, R.M., Staas, J.K., Schafer, D., Compans, R.W., Mestecky, J. J. Infect. Dis. (1993) [Pubmed]
  31. Microencapsulation of human parathyroid cells: an "in vitro" study. Picariello, L., Benvenuti, S., Recenti, R., Formigli, L., Falchetti, A., Morelli, A., Masi, L., Tonelli, F., Cicchi, P., Brandi, M.L. J. Surg. Res. (2001) [Pubmed]
  32. Antioxidant potential of two polyherbal. preparations used in Ayurveda for the treatment of rheumatoid arthritis. Thabrew, M.I., Senaratna, L., Samarawickrema, N., Munasinghe, C. Journal of ethnopharmacology. (2001) [Pubmed]
  33. Enzyme loaded biodegradable microspheres in vitro ex vivo evaluation. Genta, I., Perugini, P., Pavanetto, F., Maculotti, K., Modena, T., Casado, B., Lupi, A., Iadarola, P., Conti, B. Journal of controlled release : official journal of the Controlled Release Society. (2001) [Pubmed]
  34. Erythropoietin loaded microspheres prepared from biodegradable LPLG-PEO-LPLG triblock copolymers: protein stabilization and in-vitro release properties. Morlock, M., Kissel, T., Li, Y.X., Koll, H., Winter, G. Journal of controlled release : official journal of the Controlled Release Society. (1998) [Pubmed]
  35. Towards the preparation of a MMA-PEO block copolymer for the microencapsulation of mammalian cells. Eisa, T., Sefton, M.V. Biomaterials (1993) [Pubmed]
  36. Towards clinical testing of a single-administration tetanus vaccine based on PLA/PLGA microspheres. Johansen, P., Estevez, F., Zurbriggen, R., Merkle, H.P., Glück, R., Corradin, G., Gander, B. Vaccine (2000) [Pubmed]
  37. Agarose for a bioartificial pancreas. Iwata, H., Takagi, T., Amemiya, H., Shimizu, H., Yamashita, K., Kobayashi, K., Akutsu, T. J. Biomed. Mater. Res. (1992) [Pubmed]
  38. Determination of opium alkaloids in crude opium using non-aqueous capillary electrophoresis. Bjørnsdottir, I., Hansen, S.H. Journal of pharmaceutical and biomedical analysis. (1995) [Pubmed]
  39. Steady plasma levodopa concentrations required for good clinical response to CR-4 in patients with 'on-off'. McHale, D.M., Sage, J.I., Sonsalla, P.K., Heikkila, R.E., Duvoisin, R.C. Eur. Neurol. (1990) [Pubmed]
  40. Marked prolongation of islet xenograft survival (hamster to mouse) by microencapsulation and administration of 15-deoxyspergualin. Iwata, H., Takagi, T., Amemiya, H. Transplant. Proc. (1992) [Pubmed]
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