Disease relevance of DECAMETHYLCYCLOPENTASILOXANE

• We adsorbed swarmer cells of Serratia marcescens to polydimethylsiloxane or polystyrene [1].
• PURPOSE: In this study we evaluated the 5-year followup results of periurethral polydimethylsiloxane (PDMS) injection for female stress urinary incontinence (SUI) secondary to intrinsic sphincter deficiency (ISD) without hypermobility of the vesicourethral junction [2].
• Re: Evaluation of polydimethylsiloxane as an alternative in the endoscopic treatment of vesicoureteral reflux [3].
• The results showed no relationship between higher amounts of PDMS and capsular contracture (p = 0.74) or other symptoms (p = 0. 53) [4].
• PTFE and PDMS elicit similar foreign body reactions over time [5].

Psychiatry related information on DECAMETHYLCYCLOPENTASILOXANE

• A microfabricated catalyst reactor, prepared from glass and polydimethylsiloxane, has been directly interfaced to a gas chromatograph permitting real time reaction monitoring allowing rapid catalyst characterisation [6].

High impact information on DECAMETHYLCYCLOPENTASILOXANE

• To improve visualization and the control of cell position, we have developed a simple alternative patch clamp technique based on microfluidic junctions between a main chamber and lateral recording capillaries, all fabricated by micromolding of polydimethylsiloxane (PDMS) [7].
• Negative replicates of the chip were produced using polydimethylsiloxane silicone elastomer and these replicates were used as templates for the production of thin ( approximately 21 micrometer) membranes of collagen or gelatin [8].
• Polydimethylsiloxane (silicone rubber) disks and cellulose Millipore filters were implanted into wild-type and SPARC-null mice [9].
• As 3-D substrates, we used poly-D-lysine (PDL) coatings on microfabricated steps of polydimethylsiloxane (PDMS) and complementary features of Matrigel [10].
• The time-dependent surface property of the plasma-treated PDMS is then measured in terms of the zeta potential [11].

Chemical compound and disease context of DECAMETHYLCYCLOPENTASILOXANE

• At 1 and 6 months there were no differences in inflammation or fibrosis between PTFE and PDMS or any pretreatment combinations with saline or epinephrine [5].

Biological context of DECAMETHYLCYCLOPENTASILOXANE

• 17-beta-Estradiol, which is luteotropic in rabbits, was administered during pseudopregnancy via polydimethylsiloxane (Silastic) implants to determine the effects on serum progesterone concentrations [12].
• Integration of gene amplification and capillary gel electrophoresis on a polydimethylsiloxane-glass hybrid microchip [13].
• Hypophysectomized male rats treated with polydimethylsiloxane capsules containing testosterone: effects on spermatogenesis, fertility, and reproductive tract concentrations of androgens [14].
• A new chiral heterogeneous catalytic system obtained by occlusion of the Rh-MeDuPHOS complex in a polydimethylsiloxane film was tested in the asymmetric hydrogenation of methyl 2-acetamidoacrylate in aqueous medium [15].
• Adult male Sprague-Dawley rats received s.c. implants of estradiol-filled polydimethylsiloxane capsules of varying lengths and, after three months, were each mated twice to two females in proestrus [16].

Anatomical context of DECAMETHYLCYCLOPENTASILOXANE

• The geometry of the recording capillaries permits high-quality, stable, whole-cell seals despite the hydrophobicity of the PDMS surface [7].
• METHODS: To manipulate early focal contact, a reduced focal cell-substrate contact area on the micropatterned surfaces was implemented by microfabrication with polydimethylsiloxane (PDMS) [17].
• T was administered to intact adult male rats via sustained release polydimethylsiloxane capsules in order to experimentally clamp T at well defined concentrations within the seminiferous tubules [18].
• Premature regression of corpora lutea in pseudopregnant rabbits following the removal of polydimethylsiloxane capsules containing 17 beta-estradiol [12].
• Surgical procedures included extravesical reimplantation (291 ureters), intravesical reimplantation (48) and endoscopic polydimethylsiloxane injection (137) [19].

Associations of DECAMETHYLCYCLOPENTASILOXANE with other chemical compounds

• We examined the effect of exogenously administered testosterone (T) on the quantitative restoration of advanced spermatogenic cells in adult rat testes rendered azoospermic by treating rats with polydimethylsiloxane (PDS) implants of T and estradiol (E) [20].
• Studies were undertaken in the B6C3F1 mouse to evaluate the immunotoxicological effects of the following components of a mammary gel prosthesis: polydimethylsiloxane fluid, silicone gel, elastomer shell and a polyurethane implant cover [21].
• The amount of silicone (polydimethylsiloxane [PDMS]) in capsular tissue surgically removed from women with breast implants was measured by using (29)Si and (1)H magic-angle spinning solid-state NMR spectroscopy [4].
• The PDMS/DVB fiber was found to be the most efficient for trapping olibanum characteristic diterpenes, with a sampling time of 1 h and a sampling temperature of 80 degrees C [22].
• The biomedical polymers were polyethylene, polydimethylsiloxane, woven Dacron fabric, expanded polytetrafluoroethylene, Biomer, and tissue culture treated polystyrene as the control [23].

Gene context of DECAMETHYLCYCLOPENTASILOXANE

• Absorption spectra indicate conformational alteration of myoglobin adsorbed on polydimethylsiloxane [24].
• Hypophysectomy or sc implantation of testosterone-estradiol 17 beta (T-E) filled polydimethylsiloxane capsules for 5 days caused a dramatic reduction in testosterone secretion when testes subsequently were perfused in vitro [25].
• RESULTS: After a single injection polydimethylsiloxane cured vesicoureteral reflux in 45 ureteral units (81.8%), while in 5 (9.1%) the condition was improved [26].
• FIMS with the PDMS/DVB fiber allows simple extraction and MS detection and quantitation of DMP in water with good linearity and precision, and at concentrations as low as 3.6 microg L(-1) [27].
• Spatially well-defined protein patterns of bacterial toxins were obtained by microcontact printing using a polydimethylsiloxane (PDMS) stamp on a functionalized self-assembled monolayer on Au [28].

Analytical, diagnostic and therapeutic context of DECAMETHYLCYCLOPENTASILOXANE

• We report on a fundamental technological advance for multilayer polydimethylsiloxane (PDMS) microfluidics [29].
• Hybrid glass-polydimethylsiloxane (PDMS) wafer-scale construction is used to combine 250-nl reactors, affinity-capture purification chambers, high-performance capillary electrophoresis channels, and pneumatic valves and pumps onto a single microfabricated device [30].
• Human immune response to polydimethylsiloxane (silicone): screening studies in a breast implant population [31].
• Surface characterization using chemical force microscopy and the flow performance of modified polydimethylsiloxane for microfluidic device applications [32].
• We report on the development of a hybrid polydimethylsiloxane (PDMS)-glass microchip for genetic analysis by functional integration of polymerase chain reaction (PCR) and capillary gel electrophoresis (CGE), and on related temperature control systems for PCR on a PDMS-glass hybrid microchip [13].

References