Chemical Compound Review:
Obtusifoliol (3S,4S,5S,10S,13R,14R,17R)- 4,10,13,14...
Synonyms:
CHEMBL481434, SureCN2511101, LMST01030101, AC1L22WJ, C01943, ...
- Functional cloning of an Arabidopsis thaliana cDNA encoding cycloeucalenol cycloisomerase. Lovato, M.A., Hart, E.A., Segura, M.J., Giner, J.L., Matsuda, S.P. J. Biol. Chem. (2000)
- Sterol composition of Cryptococcus neoformans in the presence and absence of fluconazole. Ghannoum, M.A., Spellberg, B.J., Ibrahim, A.S., Ritchie, J.A., Currie, B., Spitzer, E.D., Edwards, J.E., Casadevall, A. Antimicrob. Agents Chemother. (1994)
- Crystal structure of cytochrome P450 14alpha -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors. Podust, L.M., Poulos, T.L., Waterman, M.R. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Isolation and reconstitution of the heme-thiolate protein obtusifoliol 14alpha-demethylase from Sorghum bicolor (L.) Moench. Kahn, R.A., Bak, S., Olsen, C.E., Svendsen, I., Moller, B.L. J. Biol. Chem. (1996)
- Arabidopsis cyp51 mutant shows postembryonic seedling lethality associated with lack of membrane integrity. Kim, H.B., Schaller, H., Goh, C.H., Kwon, M., Choe, S., An, C.S., Durst, F., Feldmann, K.A., Feyereisen, R. Plant Physiol. (2005)
- Lipid signaling in plants. Cloning and expression analysis of the obtusifoliol 14alpha-demethylase from Solanum chacoense Bitt., a pollination- and fertilization-induced gene with both obtusifoliol and lanosterol demethylase activity. O'Brien, M., Chantha, S.C., Rahier, A., Matton, D.P. Plant Physiol. (2005)
- Cloning and expression in Escherichia coli of the obtusifoliol 14 alpha-demethylase of Sorghum bicolor (L.) Moench, a cytochrome P450 orthologous to the sterol 14 alpha-demethylases (CYP51) from fungi and mammals. Bak, S., Kahn, R.A., Olsen, C.E., Halkier, B.A. Plant J. (1997)
- Properties and structural requirements for substrate specificity of cytochrome P-450-dependent obtusifoliol 14 alpha-demethylase from maize (Zea mays) seedlings. Taton, M., Rahier, A. Biochem. J. (1991)
- Accumulation of 3-ketosteroids induced by itraconazole in azole-resistant clinical Candida albicans isolates. Marichal, P., Gorrens, J., Laurijssens, L., Vermuyten, K., Van Hove, C., Le Jeune, L., Verhasselt, P., Sanglard, D., Borgers, M., Ramaekers, F.C., Odds, F., Vanden Bossche, H. Antimicrob. Agents Chemother. (1999)
- Virus-induced silencing of sterol biosynthetic genes: identification of a Nicotiana tabacum L. obtusifoliol-14alpha-demethylase (CYP51) by genetic manipulation of the sterol biosynthetic pathway in Nicotiana benthamiana L. Burger, C., Rondet, S., Benveniste, P., Schaller, H. J. Exp. Bot. (2003)
- Cloning and functional expression in yeast of a cDNA coding for an obtusifoliol 14alpha-demethylase (CYP51) in wheat. Cabello-Hurtado, F., Zimmerlin, A., Rahier, A., Taton, M., DeRose, R., Nedelkina, S., Batard, Y., Durst, F., Pallett, K.E., Werck-Reichhart, D. Biochem. Biophys. Res. Commun. (1997)
- CYP51 from Trypanosoma brucei is obtusifoliol-specific. Lepesheva, G.I., Nes, W.D., Zhou, W., Hill, G.C., Waterman, M.R. Biochemistry (2004)
- Oxidative C4-demethylation of 24-methylene cycloartanol by a cyanide-sensitive enzymatic system from higher plant microsomes. Pascal, S., Taton, M., Rahier, A. Biochem. Biophys. Res. Commun. (1990)