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Chemical Compound Review

AG-D-61017     tetrapropylazanium

Synonyms: CHEMBL2074857, CHEBI:55319, CTK4B6523, ZINC01669523, AR-1K0983, ...
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Psychiatry related information on tetrapropylazanium

  • The in-situ SAXS investigations show that TPA cations lead to the shortest reaction time as indicated by the observance of Bragg diffraction peaks (15 approximately 16.5 h) and the largest particle growth rate (1.9 +/- 0.1 nm/h) [1].

High impact information on tetrapropylazanium


Biological context of tetrapropylazanium

  • Precursor nanoparticles that form spontaneously on hydrolysis of tetraethylorthosilicate in aqueous solutions of tetrapropylammonium (TPA) hydroxide evolve to TPA-silicalite-1, a molecular-sieve crystal that serves as a model for the self-assembly of porous inorganic materials in the presence of organic structure-directing agents [7].

Associations of tetrapropylazanium with other chemical compounds

  • Nitro group reduction with in situN-Boc protection and THP* removal provides alpha,beta-disubstituted ethanolamine derivatives, while treatment with tetrapropylammonium perruthenate gives THP* protected alpha-hydroxy ketone derivatives in high diasteromeric excess [8].

Gene context of tetrapropylazanium


Analytical, diagnostic and therapeutic context of tetrapropylazanium

  • Tetramethyl- (TMA) and tetrapropylammonium (TPA) did not produce myogenic responses to quick stretch, and there was no potentiating effect on the responses to direct electrical stimulation or to high levels of potassium [10].


  1. Silicalite-1 growth from clear solution: Effect of the structure-directing agent on growth kinetics. Cheng, C.H., Shantz, D.F. The journal of physical chemistry. B, Condensed matter, materials, surfaces, interfaces & biophysical. (2005) [Pubmed]
  2. Internal block of human heart sodium channels by symmetrical tetra-alkylammoniums. O'Leary, M.E., Horn, R. J. Gen. Physiol. (1994) [Pubmed]
  3. Kinetics of the inhibition of the Na-K pump by tetrapropylammonium chloride. Kropp, D.L., Sachs, J.R. J. Physiol. (Lond.) (1977) [Pubmed]
  4. Fractionation of DNA from mammalian cells by alkaline elution. Kohn, K.W., Erickson, L.C., Ewig, R.A., Friedman, C.A. Biochemistry (1976) [Pubmed]
  5. Effects of barium, furosemide, ouabaine and 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid (DIDS) on ionophoretically-induced changes in extracellular potassium concentration in hippocampal slices from rats and from patients with epilepsy. Jauch, R., Windmüller, O., Lehmann, T.N., Heinemann, U., Gabriel, S. Brain Res. (2002) [Pubmed]
  6. The accumulation ratio of K+, Na+, Ca2+ and tetrapropylammonium in steady-state Mitochondria. Massari, S., Pozzan, T. Arch. Biochem. Biophys. (1976) [Pubmed]
  7. Mechanistic principles of nanoparticle evolution to zeolite crystals. Davis, T.M., Drews, T.O., Ramanan, H., He, C., Dong, J., Schnablegger, H., Katsoulakis, M.A., Kokkoli, E., McCormick, A.V., Penn, R.L., Tsapatsis, M. Nature materials. (2006) [Pubmed]
  8. Highly stereoselective oxy-Michael additions to alpha,beta-disubstituted nitro olefins: asymmetric synthesis of pseudo-norephedrine derivatives and THP* protected alpha-hydroxy ketones. Buchanan, D.J., Dixon, D.J., Hernandez-Juan, F.A. Org. Biomol. Chem. (2004) [Pubmed]
  9. Binding of inhibitory metals to yeast enolase. Elliott, J.I., Brewer, J.M. J. Inorg. Biochem. (1980) [Pubmed]
  10. Mechanism of potentiation of mechanical responses by tetraethylammonium in canine tracheal smooth muscle. Imaizumi, Y., Watanabe, M. Jpn. J. Pharmacol. (1983) [Pubmed]
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