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Gene Review

TOM1L1  -  target of myb1 (chicken)-like 1

Homo sapiens

Synonyms: OK/KNS-CL.3, SRCASM, Src-activating and signaling molecule protein, TOM1-like protein 1, Target of Myb-like protein 1
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Disease relevance of TOM1L1


High impact information on TOM1L1


Associations of TOM1L1 with chemical compounds


Biological context of TOM1L1


Anatomical context of TOM1L1


Other interactions of TOM1L1


Analytical, diagnostic and therapeutic context of TOM1L1


  1. Srcasm Corrects Fyn-induced Epidermal Hyperplasia by Kinase Down-regulation. Li, W., Marshall, C., Mei, L., Gelfand, J., Seykora, J.T. J. Biol. Chem. (2007) [Pubmed]
  2. Srcasm overexpression in psoriasis-insights into pathogenesis. Pulitzer, M., Li, W., Hanson, M., Singh, F., Elenitsas, R., Gelfand, J.M., Vanvoorhees, A., Seykora, J.T. J. Cutan. Pathol. (2007) [Pubmed]
  3. Srcasm modulates EGF and Src-kinase signaling in keratinocytes. Li, W., Marshall, C., Mei, L., Dzubow, L., Schmults, C., Dans, M., Seykora, J. J. Biol. Chem. (2005) [Pubmed]
  4. TOM1L1 is a Lyn substrate involved in FcepsilonRI signaling in mast cells. Zhang, J., Suzuki, K., Hitomi, T., Siraganian, R.P. J. Biol. Chem. (2007) [Pubmed]
  5. Endofin recruits clathrin to early endosomes via TOM1. Seet, L.F., Hong, W. J. Cell. Sci. (2005) [Pubmed]
  6. TOM1 genes map to human chromosome 22q13.1 and mouse chromosome 8C1 and encode proteins similar to the endosomal proteins HGS and STAM. Seroussi, E., Kedra, D., Kost-Alimova, M., Sandberg-Nordqvist, A.C., Fransson, I., Jacobs, J.F., Fu, Y., Pan, H.Q., Roe, B.A., Imreh, S., Dumanski, J.P. Genomics (1999) [Pubmed]
  7. 'Srcasm: a novel Src activating and signaling molecule. Seykora, J.T., Mei, L., Dotto, G.P., Stein, P.L. J. Biol. Chem. (2002) [Pubmed]
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