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Gene Review

CCDC85B  -  coiled-coil domain containing 85B

Homo sapiens

Synonyms: Coiled-coil domain-containing protein 85B, DIPA, Delta-interacting protein A, Hepatitis delta antigen-interacting protein A
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Disease relevance of CCDC85B


High impact information on CCDC85B


Chemical compound and disease context of CCDC85B


Biological context of CCDC85B


Anatomical context of CCDC85B


Associations of CCDC85B with chemical compounds

  • The ruthenium-bound dipa ligand possesses structural constraints that prevent the usual oxidative dehydrogenation reaction, which would yield exclusively the corresponding imine [8].
  • When experimental pressure is 253 torr (as at the top of Mt. Everest): (1) DIPA takes place independently of PO2; (2) ex vivo DIPA can be inhibited by menthol, thymol, piracetam and pentoxifylline [9].

Analytical, diagnostic and therapeutic context of CCDC85B

  • We analyzed the interaction between DIPA and p78 by co-immunoprecipitation and identified the structural regions involved in the interaction [6].


  1. Delta-interacting protein A and the origin of hepatitis delta antigen. Long, M., de Souza, S.J., Gilbert, W. Science (1997) [Pubmed]
  2. Cholescintigraphy in the diagnosis of Rotor syndrome. Tutus, A., Silov, G., Kula, M. Clinical nuclear medicine. (1997) [Pubmed]
  3. A cellular homolog of hepatitis delta antigen: implications for viral replication and evolution. Brazas, R., Ganem, D. Science (1996) [Pubmed]
  4. Delta-interacting protein A, a new inhibitory partner of CCAAT/enhancer-binding protein beta, implicated in adipocyte differentiation. Bezy, O., Elabd, C., Cochet, O., Petersen, R.K., Kristiansen, K., Dani, C., Ailhaud, G., Amri, E.Z. J. Biol. Chem. (2005) [Pubmed]
  5. DIPA (decompression-inducible platelet aggregation) and hemostasis: vascular occlusion and its prevention, in the web of the frog's foot. Murayama, M. Thromb. Res. (1989) [Pubmed]
  6. DIPA, which can localize to the centrosome, associates with p78/MCRS1/MSP58 and acts as a repressor of gene transcription. Du, X., Wang, Q., Hirohashi, Y., Greene, M.I. Exp. Mol. Pathol. (2006) [Pubmed]
  7. Visualization of gallstones by hepatobiliary scintigraphy. Two case reports. Garty, I. Clinical nuclear medicine. (1984) [Pubmed]
  8. Synthesis and characterization of bis(di-2-pyridylmethanamine)ruthenium(II). Chang, J., Plummer, S., Berman, E.S., Striplin, D., Blauch, D. Inorganic chemistry. (2004) [Pubmed]
  9. AMS (acute mountain sickness), a vascular occlusive disease. Murayama, M. Med. Hypotheses (1990) [Pubmed]
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