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Gene Review:

MRSS - Mental retardation, X-linked, with short...

Homo sapiens

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Disease relevance of MRSS

OBJECTIVE: To examine the validity of a durometer to objectively measure skin hardness in systemic sclerosis (SSc), and to compare digital durometry with the modified Rodnan skin score (MRSS) and ultrasonography [1].
(MRSS), and penicillin-resistant Streptococcus pneumoniae (PRSP) was evaluated [2].
METHODS: To determine the MRSS in healthy paediatric population, patients of the paediatric rheumatology out-patient clinic with mechanical pain or with juvenile idiopathic arthritis at the age of 16 yr or under were assessed between 1 January and 31 March 2004 [3].
Infections caused by methicillin-resistant Staphylococcus strains (MRSS) have become an increasing problem both as community-acquired and nosocomial infections [4].
In this study we examined the incidence of MRSS in clinical samples and compared the antibiotic susceptibility pattern of methicillin-resistant Staphylococcus aureus with that of methicillin-resistant Staphylococcus non-aureus strains [4].

High impact information on MRSS

The MICs at which 90% of isolates are inhibited for daptomycin and vancomycin, respectively, were as follows: MRSA, 1 and 2 microg/ml; MRSS, 1 and 4 microg/ml; PRSP, 1 and 0.5 microg/ml; and VREF, 2 and >64 microg/ml [2].
OBJECTIVE: This study used pharmacoeconomic modeling to evaluate the costs and outcomes associated with the use of i.v. vancomycin compared with p.o. linezolid in the treatment of MRSS-infected patients [5].
BACKGROUND: Infections with methicillin-resistant Staphylococcus species (MRSS) are associated with higher treatment costs than infections with methicillin-sensitive Staphylococcus species in the United States--partly because of an increased length of hospital stay (LOS) [5].
INTERVENTIONS: Patients were randomised to receive propofol with or without EDTA and then to 1 of 2 sedation levels: light (Modified Ramsay Sedation Scale [MRSS] score of 2 to 3) or deep (MRSS score of 4 to 5) [6].
The incidence of antibiotic resistance among MRSS was significantly higher than that among methicillin-susceptibility staphylococcal species [4].

Anatomical context of MRSS

After treatment there was a statistically significant improvement in the modified Rodnan skin score (MRSS), attack frequency of Raynaud's phenomenon (RP), and erythrocyte sedimentation rate (ESR) in the CYC-group, but not in the AZ-group [7].

Associations of MRSS with chemical compounds

Ciprofloxacin and teicoplanin were the most effective antibiotics tested against MRSS, followed in activity by vancomycin and imipenem [4].
Within MRSS the most frequent resistances were those to erythromycin and norfloxacin [4].
Subjects performed off-ice fitness tests (vertical jump, 40-yd dash, Leger test for predicting .V(O2)max) and on-ice fitness (Modified 3-Repeat Sprint Skate Test-MRSS, blood lactate after sprint test) and skating performance tests (6.10-m acceleration test, Cornering S-Turn Agility Test) [8].

Analytical, diagnostic and therapeutic context of MRSS

The mean age of the patients was 10.5 yr (2.9-16), the mean body mass index (BMI) was 18.3 (9.3-35.7), and the mean MRSS was 13.92 (range 4-25) [3].
Practical appraisal of a new rating scale (MRSS) for rehabilitation [9].

References

Durometry for the assessment of skin disease in systemic sclerosis. Kissin, E.Y., Schiller, A.M., Gelbard, R.B., Anderson, J.J., Falanga, V., Simms, R.W., Korn, J.H., Merkel, P.A. Arthritis Rheum. (2006) [Pubmed]
Comparative In vitro activities of daptomycin and vancomycin against resistant gram-positive pathogens. Snydman, D.R., Jacobus, N.V., McDermott, L.A., Lonks, J.R., Boyce, J.M. Antimicrob. Agents Chemother. (2000) [Pubmed]
Healthy children have a significantly increased skin score assessed with the modified Rodnan skin score. Foeldvari, I., Wierk, A. Rheumatology (Oxford, England) (2006) [Pubmed]
Methicillin-resistant staphylococcal strains isolated from clinical samples. Sposini, T., Bastianini, L., D'Alò, F., Verducci, N., Sbaraglia, G. Journal of chemotherapy (Florence, Italy) (1991) [Pubmed]
Cost analysis of switching from i.v. vancomycin to p.o. linezolid for the management of methicillin-resistant Staphylococcus species. McCollum, M., Rhew, D.C., Parodi, S. Clinical therapeutics. (2003) [Pubmed]
Effects of propofol containing EDTA on mineral metabolism in medical ICU patients with pulmonary dysfunction. Abraham, E., Papadakos, P.J., Tharratt, R.S., Hall, J.B., Williams, G.J. Intensive care medicine. (2000) [Pubmed]
A randomized unblinded trial of cyclophosphamide versus azathioprine in the treatment of systemic sclerosis. Nadashkevich, O., Davis, P., Fritzler, M., Kovalenko, W. Clin. Rheumatol. (2006) [Pubmed]
Physical and performance differences among forwards, defensemen, and goalies in elite women's ice hockey. Geithner, C.A., Lee, A.M., Bracko, M.R. Journal of strength and conditioning research / National Strength & Conditioning Association. (2006) [Pubmed]
Practical appraisal of a new rating scale (MRSS) for rehabilitation. Khoosal, D.I., Oswald, A.G., Smith, R.J. Journal of the Royal Society of Medicine. (1987) [Pubmed]

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