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Gene Review

EFNA4  -  ephrin-A4

Homo sapiens

Synonyms: EFL4, EPH-related receptor tyrosine kinase ligand 4, EPLG4, Ephrin-A4, LERK-4, ...
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Disease relevance of EFNA4


High impact information on EFNA4


Biological context of EFNA4


Anatomical context of EFNA4


Analytical, diagnostic and therapeutic context of EFNA4


  1. Human osteosarcoma expresses specific ephrin profiles: implications for tumorigenicity and prognosis. Varelias, A., Koblar, S.A., Cowled, P.A., Carter, C.D., Clayer, M. Cancer (2002) [Pubmed]
  2. A splice variant of human ephrin-A4 encodes a soluble molecule that is secreted by activated human B lymphocytes. Aasheim, H.C., Munthe, E., Funderud, S., Smeland, E.B., Beiske, K., Logtenberg, T. Blood (2000) [Pubmed]
  3. The genes encoding the eph-related receptor tyrosine kinase ligands LERK-1 (EPLG1, Epl1), LERK-3 (EPLG3, Epl3), and LERK-4 (EPLG4, Epl4) are clustered on human chromosome 1 and mouse chromosome 3. Cerretti, D.P., Lyman, S.D., Kozlosky, C.J., Copeland, N.G., Gilbert, D.J., Jenkins, N.A., Valentine, V., Kirstein, M.N., Shapiro, D.N., Morris, S.W. Genomics (1996) [Pubmed]
  4. Characterization of the human ephrin-A4 promoter. Munthe, E., Aasheim, H.C. Biochem. J. (2002) [Pubmed]
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