Gene Review:
EFNB2 - ephrin-B2
Homo sapiens
Synonyms:
EPH-related receptor tyrosine kinase ligand 5, EPLG5, Ephrin-B2, HTK ligand, HTK-L, ...
- Expression profile of EFNB1, EFNB2, two ligands of EPHB2 in human gastric cancer. Kataoka, H., Tanaka, M., Kanamori, M., Yoshii, S., Ihara, M., Wang, Y.J., Song, J.P., Li, Z.Y., Arai, H., Otsuki, Y., Kobayashi, T., Konno, H., Hanai, H., Sugimura, H. J. Cancer Res. Clin. Oncol. (2002)
- Prognostic significance of EPHB6, EFNB2, and EFNB3 expressions in neuroblastoma. Tang, X.X., Zhao, H., Robinson, M.E., Cnaan, A., London, W., Cohn, S.L., Cheung, N.K., Brodeur, G.M., Evans, A.E., Ikegaki, N. Med. Pediatr. Oncol. (2000)
- Comparative integromics on Ephrin family. Katoh, Y., Katoh, M. Oncol. Rep. (2006)
- Overexpression of Lerk-5/Eplg5 messenger RNA: a novel marker for increased tumorigenicity and metastatic potential in human malignant melanomas. Vogt, T., Stolz, W., Welsh, J., Jung, B., Kerbel, R.S., Kobayashi, H., Landthaler, M., McClelland, M. Clin. Cancer Res. (1998)
- Activation of the receptor EphB4 by its specific ligand ephrin B2 in human osteoarthritic subchondral bone osteoblasts. Kwan Tat, S., Pelletier, J.P., Amiable, N., Boileau, C., Lajeunesse, D., Duval, N., Martel-Pelletier, J. Arthritis Rheum. (2008)
- Ephs and ephrins close ranks. Cutforth, T., Harrison, C.J. Trends Neurosci. (2002)
- Disruption of Eph/ephrin signaling affects migration and proliferation in the adult subventricular zone. Conover, J.C., Doetsch, F., Garcia-Verdugo, J.M., Gale, N.W., Yancopoulos, G.D., Alvarez-Buylla, A. Nat. Neurosci. (2000)
- The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway. Noren, N.K., Foos, G., Hauser, C.A., Pasquale, E.B. Nat. Cell Biol. (2006)
- Eph family transmembrane ligands can mediate repulsive guidance of trunk neural crest migration and motor axon outgrowth. Wang, H.U., Anderson, D.J. Neuron (1997)
- Establishment of a Nipah virus rescue system. Yoneda, M., Guillaume, V., Ikeda, F., Sakuma, Y., Sato, H., Wild, T.F., Kai, C. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Expression of receptor tyrosine kinase HTK (hepatoma transmembrane kinase) and HTK ligand by human leukemia-lymphoma cell lines. Steube, K.G., Meyer, C., Habig, S., Uphoff, C.C., Drexler, H.G. Leuk. Lymphoma (1999)
- Ephrin-B2 induces migration of endothelial cells through the phosphatidylinositol-3 kinase pathway and promotes angiogenesis in adult vasculature. Maekawa, H., Oike, Y., Kanda, S., Ito, Y., Yamada, Y., Kurihara, H., Nagai, R., Suda, T. Arterioscler. Thromb. Vasc. Biol. (2003)
- Ephrin-B2 ligand is a functional receptor for Hendra virus and Nipah virus. Bonaparte, M.I., Dimitrov, A.S., Bossart, K.N., Crameri, G., Mungall, B.A., Bishop, K.A., Choudhry, V., Dimitrov, D.S., Wang, L.F., Eaton, B.T., Broder, C.C. Proc. Natl. Acad. Sci. U.S.A. (2005)
- The Role of the Vascular Endothelial Growth Factor-Delta-like 4 Ligand/Notch4-Ephrin B2 Cascade in Tumor Vessel Remodeling and Endothelial Cell Functions. Hainaud, P., Contrerès, J.O., Villemain, A., Liu, L.X., Plouët, J., Tobelem, G., Dupuy, E. Cancer Res. (2006)
- Effects of overexpression of ephrin-B2 on tumour growth in human colorectal cancer. Liu, W., Jung, Y.D., Ahmad, S.A., McCarty, M.F., Stoeltzing, O., Reinmuth, N., Fan, F., Ellis, L.M. Br. J. Cancer (2004)
- Characterization of a ligand for receptor protein-tyrosine kinase HTK expressed in immature hematopoietic cells. Sakano, S., Serizawa, R., Inada, T., Iwama, A., Itoh, A., Kato, C., Shimizu, Y., Shinkai, F., Shimizu, R., Kondo, S., Ohno, M., Suda, T. Oncogene (1996)
- Ephrin-B2 is a candidate ligand for the Eph receptor, EphB6. Munthe, E., Rian, E., Holien, T., Rasmussen, A., Levy, F.O., Aasheim, H. FEBS Lett. (2000)
- Coexpression of ephrin-Bs and their receptors in colon carcinoma. Liu, W., Ahmad, S.A., Jung, Y.D., Reinmuth, N., Fan, F., Bucana, C.D., Ellis, L.M. Cancer (2002)
- Specification of distinct dopaminergic neural pathways: roles of the Eph family receptor EphB1 and ligand ephrin-B2. Yue, Y., Widmer, D.A., Halladay, A.K., Cerretti, D.P., Wagner, G.C., Dreyer, J.L., Zhou, R. J. Neurosci. (1999)
- Biphasic functions of the kinase-defective Ephb6 receptor in cell adhesion and migration. Matsuoka, H., Obama, H., Kelly, M.L., Matsui, T., Nakamoto, M. J. Biol. Chem. (2005)
- Cell-type specific and estrogen dependent expression of the receptor tyrosine kinase EphB4 and its ligand ephrin-B2 during mammary gland morphogenesis. Nikolova, Z., Djonov, V., Zuercher, G., Andres, A.C., Ziemiecki, A. J. Cell. Sci. (1998)
- Engineered fibrin matrices for functional display of cell membrane-bound growth factor-like activities: study of angiogenic signaling by ephrin-B2. Zisch, A.H., Zeisberger, S.M., Ehrbar, M., Djonov, V., Weber, C.C., Ziemiecki, A., Pasquale, E.B., Hubbell, J.A. Biomaterials (2004)
- Graded and lamina-specific distributions of ligands of EphB receptor tyrosine kinases in the developing retinotectal system. Braisted, J.E., McLaughlin, T., Wang, H.U., Friedman, G.C., Anderson, D.J., O'leary, D.D. Dev. Biol. (1997)
- Association among EPHB2, TrkA, and MYCN expression in low-stage neuroblastomas. Tang, X.X., Evans, A.E., Zhao, H., Cnaan, A., Brodeur, G.M., Ikegaki, N. Med. Pediatr. Oncol. (2001)
- Ena/VASP proteins mediate repulsion from ephrin ligands. Evans, I.R., Renne, T., Gertler, F.B., Nobes, C.D. J. Cell. Sci. (2007)
- Ephrin-B2 is differentially expressed in the intestinal epithelium in Crohn's disease and contributes to accelerated epithelial wound healing in vitro. Hafner, C., Meyer, S., Langmann, T., Schmitz, G., Bataille, F., Hagen, I., Becker, B., Roesch, A., Rogler, G., Landthaler, M., Vogt, T. World J. Gastroenterol. (2005)
- Assignments of the GAS6, POSTN and EFNB2 genes to SSC11 by somatic cell and radiation hybrid panels. Ma, H., Liu, X., Shi, Q., He, C., Yerle, M., Ren, H., Li, K. Anim. Genet. (2005)