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Gene Review

Rcn1  -  reticulocalbin 1

Mus musculus

Synonyms: Rca1, Rcn, Reticulocalbin-1
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High impact information on Rcn1


Biological context of Rcn1


Anatomical context of Rcn1

  • When hepatic cytosols and microsomes from calves treated with a combination of GPAs were analyzed by 2-DE, we found changes in the expression of two proteins, which we identified as adenosine kinase and reticulocalbin [9].

Physical interactions of Rcn1

  • Thus, reticulocalbin differs from the cytosolic Ca(2+)-binding protein calbindin D28 which also has six EF-hand motif domains, but the gene for which is divided into 11 exons [8].


  1. DNA supercoiling factor localizes to puffs on polytene chromosomes in Drosophila melanogaster. Kobayashi, M., Aita, N., Hayashi, S., Okada, K., Ohta, T., Hirose, S. Mol. Cell. Biol. (1998) [Pubmed]
  2. Reticulocalbin, a novel endoplasmic reticulum resident Ca(2+)-binding protein with multiple EF-hand motifs and a carboxyl-terminal HDEL sequence. Ozawa, M., Muramatsu, T. J. Biol. Chem. (1993) [Pubmed]
  3. Gene expression analysis of an H(2)O(2)-resistant lens epithelial cell line. Carper, D., John, M., Chen, Z., Subramanian, S., Wang, R., Ma, W., Spector, A. Free Radic. Biol. Med. (2001) [Pubmed]
  4. Separation and sequencing of familiar and novel murine proteins using preparative two-dimensional gel electrophoresis. Merrick, B.A., Patterson, R.M., Witcher, L.L., He, C., Selkirk, J.K. Electrophoresis (1994) [Pubmed]
  5. Modifications of the retina neuronal populations of the heterozygous mutant small eye mouse, the Sey(Dey). Curto, G.G., Lara, J.M., Parrilla, M., Aij??n, J., Velasco, A. Brain Res. (2007) [Pubmed]
  6. The reticulocalbin gene maps to the WAGR region in human and to the Small eye Harwell deletion in mouse. Kent, J., Lee, M., Schedl, A., Boyle, S., Fantes, J., Powell, M., Rushmere, N., Abbott, C., van Heyningen, V., Bickmore, W.A. Genomics (1997) [Pubmed]
  7. Cloning of a human homologue of mouse reticulocalbin reveals conservation of structural domains in the novel endoplasmic reticulum resident Ca(2+)-binding protein with multiple EF-hand motifs. Ozawa, M. J. Biochem. (1995) [Pubmed]
  8. Structure of the gene encoding mouse reticulocalbin, a novel endoplasmic reticulum-resident Ca(2+)-binding protein with multiple EF-hand motifs. Ozawa, M. J. Biochem. (1995) [Pubmed]
  9. Proteomic investigation in the detection of the illicit treatment of calves with growth-promoting agents. Gardini, G., Del Boccio, P., Colombatto, S., Testore, G., Corpillo, D., Di Ilio, C., Urbani, A., Nebbia, C. Proteomics (2006) [Pubmed]
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