Gene Review:
Hspa1b - heat shock protein 1B
Mus musculus
Synonyms:
HSP70.1, HSP70A1, Hcp70.1, Heat shock 70 kDa protein 1, Heat shock 70 kDa protein 1B, ...
Rallu,
Loones,
Lallemand,
Morimoto,
Morange,
Mezger,
Christians,
Michel,
Adenot,
Mezger,
Rallu,
Morange,
Renard,
Novoselova,
Glushkova,
Cherenkov,
Chudnovsky,
Fesenko,
Calabrese,
Scapagnini,
Ravagna,
Fariello,
Giuffrida Stella,
Abraham,
Koller,
Mohajeri,
Huber,
Wollmer,
Roth Z'graggen,
Sandmeier,
Moritz,
Tracy,
Nitsch,
Christen,
Hansson,
Nylandsted,
Castilho,
Leist,
Jäättelä,
Brundin,
Dix,
Garges,
Hong,
- Deletion of the inducible 70-kDa heat shock protein genes in mice impairs cardiac contractile function and calcium handling associated with hypertrophy. Kim, Y.K., Suarez, J., Hu, Y., McDonough, P.M., Boer, C., Dix, D.J., Dillmann, W.H. Circulation (2006)
- Effects of hsp70.1 gene knockout on the mitochondrial apoptotic pathway after focal cerebral ischemia. Lee, S.H., Kwon, H.M., Kim, Y.J., Lee, K.M., Kim, M., Yoon, B.W. Stroke (2004)
- Spontaneous activation of pancreas trypsinogen in heat shock protein 70.1 knock-out mice. Hwang, J.H., Ryu, J.K., Yoon, Y.B., Lee, K.H., Park, Y.S., Kim, J.W., Kim, N., Lee, D.H., Jeong, J.B., Seo, J.S., Kim, Y.T. Pancreas (2005)
- Active immunization of mice with an Abeta-Hsp70 vaccine. Koller, M.F., Mohajeri, M.H., Huber, M., Wollmer, M.A., Roth Z'graggen, B.V., Sandmeier, E., Moritz, E., Tracy, J., Nitsch, R.M., Christen, P. Neuro-degenerative diseases. (2004)
- 17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration. Waza, M., Adachi, H., Katsuno, M., Minamiyama, M., Sang, C., Tanaka, F., Inukai, A., Doyu, M., Sobue, G. Nat. Med. (2005)
- T-complex polypeptide-1 is a subunit of a heteromeric particle in the eukaryotic cytosol. Lewis, V.A., Hynes, G.M., Zheng, D., Saibil, H., Willison, K. Nature (1992)
- CD40, but not CD40L, is required for the optimal priming of T cells and control of aerosol M. tuberculosis infection. Lazarevic, V., Myers, A.J., Scanga, C.A., Flynn, J.L. Immunity (2003)
- Distinct stimulus-specific histone modifications at hsp70 chromatin targeted by the transcription factor heat shock factor-1. Thomson, S., Hollis, A., Hazzalin, C.A., Mahadevan, L.C. Mol. Cell (2004)
- Hypoglycemia enhances the expression of prion protein and heat-shock protein 70 in a mouse neuroblastoma cell line. Shyu, W.C., Chen, C.P., Saeki, K., Kubosaki, A., Matusmoto, Y., Onodera, T., Ding, D.C., Chiang, M.F., Lee, Y.J., Lin, S.Z., Li, H. J. Neurosci. Res. (2005)
- Induction of antibodies against murine full-length prion protein in wild-type mice. Koller, M.F., Grau, T., Christen, P. J. Neuroimmunol. (2002)
- Overexpression of heat shock protein 70 in R6/2 Huntington's disease mice has only modest effects on disease progression. Hansson, O., Nylandsted, J., Castilho, R.F., Leist, M., Jäättelä, M., Brundin, P. Brain Res. (2003)
- Nonsteroidal anti-inflammatory drugs differentially affect the heat shock response in cultured spinal cord cells. Batulan, Z., Nalbantoglu, J., Durham, H.D. Cell Stress Chaperones (2005)
- Tumor prevention and antitumor immunity with heat shock protein 70 induced by 15-deoxy-delta12,14-prostaglandin J2 in transgenic adenocarcinoma of mouse prostate cells. Vanaja, D.K., Grossmann, M.E., Celis, E., Young, C.Y. Cancer Res. (2000)
- Function and regulation of heat shock factor 2 during mouse embryogenesis. Rallu, M., Loones, M., Lallemand, Y., Morimoto, R., Morange, M., Mezger, V. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Evidence for the involvement of mouse heat shock factor 1 in the atypical expression of the HSP70.1 heat shock gene during mouse zygotic genome activation. Christians, E., Michel, E., Adenot, P., Mezger, V., Rallu, M., Morange, M., Renard, J.P. Mol. Cell. Biol. (1997)
- Heat shock protein-70 mediates the cytoprotective effect of carbon monoxide: involvement of p38 beta MAPK and heat shock factor-1. Kim, H.P., Wang, X., Zhang, J., Suh, G.Y., Benjamin, I.J., Ryter, S.W., Choi, A.M. J. Immunol. (2005)
- Targeted disruption of hsp70.1 sensitizes to osmotic stress. Shim, E.H., Kim, J.I., Bang, E.S., Heo, J.S., Lee, J.S., Kim, E.Y., Lee, J.E., Park, W.Y., Kim, S.H., Kim, H.S., Smithies, O., Jang, J.J., Jin, D.I., Seo, J.S. EMBO Rep. (2002)
- Early transcriptional activation of the hsp70.1 gene by osmotic stress in one-cell embryos of the mouse. Fiorenza, M.T., Bevilacqua, A., Canterini, S., Torcia, S., Pontecorvi, M., Mangia, F. Biol. Reprod. (2004)
- Inhibition of hsp70-1 and hsp70-3 expression disrupts preimplantation embryogenesis and heightens embryo sensitivity to arsenic. Dix, D.J., Garges, J.B., Hong, R.L. Mol. Reprod. Dev. (1998)
- Effects of low-power laser radiation on mice immunity. Novoselova, E.G., Glushkova, O.V., Cherenkov, D.A., Chudnovsky, V.M., Fesenko, E.E. Photodermatology, photoimmunology & photomedicine. (2006)
- CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation. Petrucelli, L., Dickson, D., Kehoe, K., Taylor, J., Snyder, H., Grover, A., De Lucia, M., McGowan, E., Lewis, J., Prihar, G., Kim, J., Dillmann, W.H., Browne, S.E., Hall, A., Voellmy, R., Tsuboi, Y., Dawson, T.M., Wolozin, B., Hardy, J., Hutton, M. Hum. Mol. Genet. (2004)
- Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity. Jana, N.R., Tanaka, M., Wang, G., Nukina, N. Hum. Mol. Genet. (2000)
- Regional distribution of heme oxygenase, HSP70, and glutathione in brain: relevance for endogenous oxidant/antioxidant balance and stress tolerance. Calabrese, V., Scapagnini, G., Ravagna, A., Fariello, R.G., Giuffrida Stella, A.M., Abraham, N.G. J. Neurosci. Res. (2002)
- Brain-derived heat shock protein 70-peptide complexes induce NK cell-dependent tolerance to experimental autoimmune encephalomyelitis. Galazka, G., Stasiolek, M., Walczak, A., Jurewicz, A., Zylicz, A., Brosnan, C.F., Raine, C.S., Selmaj, K.W. J. Immunol. (2006)
- Evidence of an interaction between Mos and Hsp70: a role of the Mos residue serine 3 in mediating Hsp70 association. Liu, H., Vuyyuru, V.B., Pham, C.D., Yang, Y., Singh, B. Oncogene (1999)
- The role of tonicity responsive enhancer sites in the transcriptional regulation of human hsp70-2 in response to hypertonic stress. Heo, J.I., Lee, M.S., Kim, J.H., Lee, J.S., Kim, J., Park, J.B., Lee, J.Y., Han, J.A., Kim, J.I. Exp. Mol. Med. (2006)
- Heat-induced transcription from RNA polymerases II and III and HSF binding activity are co-ordinately regulated by the products of the heat shock genes. Price, B.D., Calderwood, S.K. J. Cell. Physiol. (1992)
- Effects of schisandrin B pretreatment on tumor necrosis factor-alpha induced apoptosis and Hsp70 expression in mouse liver. Ip, S.P., Che, C.T., Kong, Y.C., Ko, K.M. Cell Stress Chaperones (2001)
- Hsp70 inhibits lipopolysaccharide-induced NF-kappaB activation by interacting with TRAF6 and inhibiting its ubiquitination. Chen, H., Wu, Y., Zhang, Y., Jin, L., Luo, L., Xue, B., Lu, C., Zhang, X., Yin, Z. FEBS Lett. (2006)
- Enhanced ubiquitinylation of heat shock protein 90 as a potential mechanism for mitotic cell death in cancer cells induced with hypericin. Blank, M., Mandel, M., Keisari, Y., Meruelo, D., Lavie, G. Cancer Res. (2003)
- HSP70 deficiency results in activation of c-Jun N-terminal Kinase, extracellular signal-regulated kinase, and caspase-3 in hyperosmolarity-induced apoptosis. Lee, J.S., Lee, J.J., Seo, J.S. J. Biol. Chem. (2005)
- Three Hsp70 genes are located in the C4-H-2D region: possible candidates for the Orch-1 locus. Snoek, M., Jansen, M., Olavesen, M.G., Campbell, R.D., Teuscher, C., van Vugt, H. Genomics (1993)
- Protective effect of heat shock proteins 70.1 and 70.3 on retinal photic injury after systemic hyperthermia. Kim, J.H., Kim, J.H., Yu, Y.S., Jeong, S.M., Kim, K.W. Korean journal of ophthalmology : KJO. (2005)
- Genomic instability and enhanced radiosensitivity in Hsp70.1- and Hsp70.3-deficient mice. Hunt, C.R., Dix, D.J., Sharma, G.G., Pandita, R.K., Gupta, A., Funk, M., Pandita, T.K. Mol. Cell. Biol. (2004)