Gene Review:
Nlrp3 - NLR family, pyrin domain containing 3
Mus musculus
Synonyms:
AGTAVPRL, AII/AVP, Cias1, Cold autoinflammatory syndrome 1 protein homolog, Cryopyrin, ...
- Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Sutterwala, F.S., Ogura, Y., Szczepanik, M., Lara-Tejero, M., Lichtenberger, G.S., Grant, E.P., Bertin, J., Coyle, A.J., Galán, J.E., Askenase, P.W., Flavell, R.A. Immunity (2006)
- IL-1 beta breaks tolerance through expansion of CD25+ effector T cells. O'Sullivan, B.J., Thomas, H.E., Pai, S., Santamaria, P., Iwakura, Y., Steptoe, R.J., Kay, T.W., Thomas, R. J. Immunol. (2006)
- Induction of PYPAF1 during in vitro maturation of mouse mast cells. Kikuchi-Yanoshita, R., Taketomi, Y., Koga, K., Sugiki, T., Atsumi, Y., Saito, T., Ishii, S., Hisada, M., Suzuki-Nishimura, T., Uchida, M.K., Moon, T.C., Chang, H.W., Sawada, M., Inagaki, N., Nagai, H., Murakami, M., Kudo, I. J. Biochem. (2003)
- Plasmodium falciparum: isolation of intact and erythrocyte-free trophozoites from sorbitol lysates. Hoppe, H.C., Coetzee, J., Louw, A.I. Parasitology (1992)
- Matthew-Wood syndrome: Report of two new cases supporting autosomal recessive inheritance and exclusion of FGF10 and FGFR2. Martinovic-Bouriel, J., Bernabé-Dupont, C., Golzio, C., Grattagliano-Bessières, B., Malan, V., Bonnière, M., Esculpavit, C., Fallet-Bianco, C., Mirlesse, V., Le Bidois, J., Aubry, M.C., Vekemans, M., Morichon, N., Etchevers, H., Attié-Bitach, T., Encha-Razavi, F., Benachi, A. Am. J. Med. Genet. A (2007)
- Cryopyrin activates the inflammasome in response to toxins and ATP. Mariathasan, S., Weiss, D.S., Newton, K., McBride, J., O'Rourke, K., Roose-Girma, M., Lee, W.P., Weinrauch, Y., Monack, D.M., Dixit, V.M. Nature (2006)
- Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Kanneganti, T.D., Ozören, N., Body-Malapel, M., Amer, A., Park, J.H., Franchi, L., Whitfield, J., Barchet, W., Colonna, M., Vandenabeele, P., Bertin, J., Coyle, A., Grant, E.P., Akira, S., Núñez, G. Nature (2006)
- Gout-associated uric acid crystals activate the NALP3 inflammasome. Martinon, F., Pétrilli, V., Mayor, A., Tardivel, A., Tschopp, J. Nature (2006)
- Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling. Kanneganti, T.D., Lamkanfi, M., Kim, Y.G., Chen, G., Park, J.H., Franchi, L., Vandenabeele, P., Núñez, G. Immunity (2007)