Chemical Compound Review:
Gulitol (2R,3S,4S,5S)-hexane- 1,2,3,4,5,6-hexol
Synonyms:
D-Gulitol, L-Glucitol, L-Sorbitol, AG-K-71750, CHEBI:28789, ...
- Sorbitol, phosphoinositides, and sodium-potassium-ATPase in the pathogenesis of diabetic complications. Greene, D.A., Lattimer, S.A., Sima, A.A. N. Engl. J. Med. (1987)
- Regeneration and repair of myelinated fibers in sural-nerve biopsy specimens from patients with diabetic neuropathy treated with sorbinil. Sima, A.A., Bril, V., Nathaniel, V., McEwen, T.A., Brown, M.B., Lattimer, S.A., Greene, D.A. N. Engl. J. Med. (1988)
- The treatment of pulmonary edema in the absence of renal function. A role for sorbitol and furosemide. Anderson, C.C., Shahvari, M.B., Zimmerman, J.E. JAMA (1979)
- Osmoprotective activity for Escherichia coli in mammalian renal inner medulla and urine. Correlation of glycine and proline betaines and sorbitol with response to osmotic loads. Chambers, S.T., Kunin, C.M. J. Clin. Invest. (1987)
- Effect of sorbitol on psychomotor function: its use in alcoholic cirrhosis. McClain, C.J., Kromhout, J.P., Zieve, L., Duane, W.C. Arch. Intern. Med. (1981)
- Mechanical hyperalgesia correlates with insulin deficiency in normoglycemic streptozotocin-treated rats. Romanovsky, D., Cruz, N.F., Dienel, G.A., Dobretsov, M. Neurobiol. Dis. (2006)
- Elevated sorbitol concentration in the cerebrospinal fluid of patients with mood disorders. Regenold, W.T., Kling, M.A., Hauser, P. Psychoneuroendocrinology (2000)
- Sorbitol catharsis does not enhance efficacy of charcoal in a simulated acetaminophen overdose. McNamara, R.M., Aaron, C.K., Gemborys, M., Davidheiser, S. Annals of emergency medicine. (1988)
- Peracetylated 1,6-dibromo-D-glucitol as efficient precursor of 1,6-diiodo and some mono-, disubstituted and heterocyclic D-glucitol derivatives. Halila, S., Benazza, M., Demailly, G. Carbohydr. Res. (2003)
- The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2. Lu, Z., Xu, S., Joazeiro, C., Cobb, M.H., Hunter, T. Mol. Cell (2002)
- Knob-positive and knob-negative Plasmodium falciparum differ in expression of a strain-specific malarial antigen on the surface of infected erythrocytes. Aley, S.B., Sherwood, J.A., Howard, R.J. J. Exp. Med. (1984)
- Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock. Uhlik, M.T., Abell, A.N., Johnson, N.L., Sun, W., Cuevas, B.D., Lobel-Rice, K.E., Horne, E.A., Dell'Acqua, M.L., Johnson, G.L. Nat. Cell Biol. (2003)
- Effects of insulin and dietary myoinositol on impaired peripheral motor nerve conduction velocity in acute streptozotocin diabetes. Greene, D.A., De Jesus, P.V., Winegrad, A.I. J. Clin. Invest. (1975)
- Role of sorbitol accumulation and myo-inositol depletion in paranodal swelling of large myelinated nerve fibers in the insulin-deficient spontaneously diabetic bio-breeding rat. Reversal by insulin replacement, an aldose reductase inhibitor, and myo-inositol. Greene, D.A., Chakrabarti, S., Lattimer, S.A., Sima, A.A. J. Clin. Invest. (1987)
- Effects of hypernatremia on organic brain osmoles. Lien, Y.H., Shapiro, J.I., Chan, L. J. Clin. Invest. (1990)
- Red blood cell sorbitol as an indicator of polyol pathway activity. Inhibition by sorbinil in insulin-dependent diabetic subjects. Malone, J.I., Leavengood, H., Peterson, M.J., O'Brien, M.M., Page, M.G., Aldinger, C.E. Diabetes (1984)
- The linked roles of nitric oxide, aldose reductase and, (Na+,K+)-ATPase in the slowing of nerve conduction in the streptozotocin diabetic rat. Stevens, M.J., Dananberg, J., Feldman, E.L., Lattimer, S.A., Kamijo, M., Thomas, T.P., Shindo, H., Sima, A.A., Greene, D.A. J. Clin. Invest. (1994)
- Sorbitol, osmoregulation, and the complications of diabetes. Burg, M.B., Kador, P.F. J. Clin. Invest. (1988)
- Sorbitol dehydrogenase is a zinc enzyme. Jeffery, J., Chesters, J., Mills, C., Sadler, P.J., Jörnvall, H. EMBO J. (1984)
- The UDP-Glc:Glycoprotein glucosyltransferase is essential for Schizosaccharomyces pombe viability under conditions of extreme endoplasmic reticulum stress. Fanchiotti, S., Fernández, F., D'Alessio, C., Parodi, A.J. J. Cell Biol. (1998)
- Activation of protein kinase C by elevation of glucose concentration: proposal for a mechanism in the development of diabetic vascular complications. Lee, T.S., Saltsman, K.A., Ohashi, H., King, G.L. Proc. Natl. Acad. Sci. U.S.A. (1989)
- Differential regulation of protein kinase C and (Na,K)-adenosine triphosphatase activities by elevated glucose levels in retinal capillary endothelial cells. Lee, T.S., MacGregor, L.C., Fluharty, S.J., King, G.L. J. Clin. Invest. (1989)
- Digestion and absorption in the human intestine of three sugar alcohols. Beaugerie, L., Flourié, B., Marteau, P., Pellier, P., Franchisseur, C., Rambaud, J.C. Gastroenterology (1990)
- Steady-state extrarenal sorbitol clearance as a measure of hepatic plasma flow. Zeeh, J., Lange, H., Bosch, J., Pohl, S., Loesgen, H., Eggers, R., Navasa, M., Chesta, J., Bircher, J. Gastroenterology (1988)
- Isolation of liver lysosomes by iron loading. Ultrastructural characterization. Glaumann, H., Jansson, H., Arborgh, B., Ericsson, J.L. J. Cell Biol. (1975)
- Contact inhibition of phagocytosis in epithelial sheets: alterations of cell surface properties induced by cell-cell contacts. Vasiliev, J.M., Gelfand, I.M., Domnina, L.V., Zacharova, O.S., Ljubimov, A.V. Proc. Natl. Acad. Sci. U.S.A. (1975)
- Diabetic cataracts and flavonoids. Varma, S.D., Mizuno, A., Kinoshita, J.H. Science (1977)
- Vascular dysfunction induced by elevated glucose levels in rats is mediated by vascular endothelial growth factor. Tilton, R.G., Kawamura, T., Chang, K.C., Ido, Y., Bjercke, R.J., Stephan, C.C., Brock, T.A., Williamson, J.R. J. Clin. Invest. (1997)
- An ABA and GA modulated gene expressed in the barley embryo encodes an aldose reductase related protein. Bartels, D., Engelhardt, K., Roncarati, R., Schneider, K., Rotter, M., Salamini, F. EMBO J. (1991)
- Regulation of carbohydrate metabolism by 2,5-anhydro-D-mannitol. Riquelme, P.T., Wernette-Hammond, M.E., Kneer, N.M., Lardy, H.A. Proc. Natl. Acad. Sci. U.S.A. (1983)
- Modulation of renal-specific oxidoreductase/myo-inositol oxygenase by high-glucose ambience. Nayak, B., Xie, P., Akagi, S., Yang, Q., Sun, L., Wada, J., Thakur, A., Danesh, F.R., Chugh, S.S., Kanwar, Y.S. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Altered aldose reductase gene regulation in cultured human retinal pigment epithelial cells. Henry, D.N., Del Monte, M., Greene, D.A., Killen, P.D. J. Clin. Invest. (1993)
- Oxidative stress-induced destruction of the yeast C-type cyclin Ume3p requires phosphatidylinositol-specific phospholipase C and the 26S proteasome. Cooper, K.F., Mallory, M.J., Strich, R. Mol. Cell. Biol. (1999)
- Activation of extracellular signal-regulated protein kinase 5 downregulates FasL upon osmotic stress. Wang, X., Finegan, K.G., Robinson, A.C., Knowles, L., Khosravi-Far, R., Hinchliffe, K.A., Boot-Handford, R.P., Tournier, C. Cell Death Differ. (2006)
- Characterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamily. Chen, W., Yazicioglu, M., Cobb, M.H. J. Biol. Chem. (2004)
- Cellular stresses differentially activate c-Jun N-terminal protein kinases and extracellular signal-regulated protein kinases in cultured ventricular myocytes. Bogoyevitch, M.A., Ketterman, A.J., Sugden, P.H. J. Biol. Chem. (1995)
- Characterization of specific pancreatic polypeptide receptors on basolateral membranes of the canine small intestine. Gilbert, W.R., Frank, B.H., Gavin, J.R., Gingerich, R.L. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Purification of vacuoles from Neurospora crassa. Vaughn, L.E., Davis, R.H. Mol. Cell. Biol. (1981)
- Red cell sorbitol: an indicator of diabetic control. Malone, J.I., Knox, G., Benford, S., Tedesco, T.A. Diabetes (1980)
- Action of sorbinil in diabetic peripheral nerve. Relationship of polyol (sorbitol) pathway inhibition to a myo-inositol-mediated defect in sodium-potassium ATPase activity. Greene, D.A., Lattimer, S.A. Diabetes (1984)
- Na+-K+-ATPase pumping activity is not directly linked to myo-inositol levels after sorbinil treatment in lenses of diabetic rats. Yeh, L.A., Rafford, C.E., Goddu, K.J., Ashton, M.A., Beyer, T.A., Hutson, N.J. Diabetes (1987)