Gene Review:
UNC5B - unc-5 homolog B (C. elegans)
Homo sapiens
Synonyms:
Netrin receptor UNC5B, P53RDL1, Protein unc-5 homolog 2, Protein unc-5 homolog B, UNC5H2, ...
- The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment. Thiebault, K., Mazelin, L., Pays, L., Llambi, F., Joly, M.O., Scoazec, J.Y., Saurin, J.C., Romeo, G., Mehlen, P. Proc. Natl. Acad. Sci. U.S.A. (2003)
- p53RDL1 regulates p53-dependent apoptosis. Tanikawa, C., Matsuda, K., Fukuda, S., Nakamura, Y., Arakawa, H. Nat. Cell Biol. (2003)
- The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase. Llambi, F., Lourenço, F.C., Gozuacik, D., Guix, C., Pays, L., Del Rio, G., Kimchi, A., Mehlen, P. EMBO J. (2005)
- Gene expression changes and signaling events associated with the direct antimelanoma effect of IFN-gamma. Gollob, J.A., Sciambi, C.J., Huang, Z., Dressman, H.K. Cancer Res. (2005)
- p53, apoptosis and axon-guidance molecules. Arakawa, H. Cell Death Differ. (2005)
- Modulation of G(ialpha(2)) signaling by the axonal guidance molecule UNC5H2. Komatsuzaki, K., Dalvin, S., Kinane, T.B. Biochem. Biophys. Res. Commun. (2002)
- Guidance of vascular and neural network formation. Eichmann, A., Le Noble, F., Autiero, M., Carmeliet, P. Curr. Opin. Neurobiol. (2005)
- Structure of the UNC5H2 death domain. Handa, N., Kukimoto-Niino, M., Akasaka, R., Murayama, K., Terada, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Nunokawa, E., Tanaka, A., Hayashizaki, Y., Kigawa, T., Shirouzu, M., Yokoyama, S. Acta Crystallogr. D Biol. Crystallogr. (2006)