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Gene Review

ALDOA  -  aldolase A, fructose-bisphosphate

Homo sapiens

Synonyms: ALDA, Fructose-bisphosphate aldolase A, GSD12, HEL-S-87p, Lung cancer antigen NY-LU-1, ...
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Disease relevance of ALDOA


High impact information on ALDOA


Biological context of ALDOA

  • The results of RNA and DNA blot analyses indicated that the human ALDOA gene is located on chromosome 16 [3].

Analytical, diagnostic and therapeutic context of ALDOA


  1. Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1. Semenza, G.L., Jiang, B.H., Leung, S.W., Passantino, R., Concordet, J.P., Maire, P., Giallongo, A. J. Biol. Chem. (1996) [Pubmed]
  2. Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr). Yao, D.C., Tolan, D.R., Murray, M.F., Harris, D.J., Darras, B.T., Geva, A., Neufeld, E.J. Blood (2004) [Pubmed]
  3. Molecular gene mapping of human aldolase A (ALDOA) gene to chromosome 16. Kukita, A., Yoshida, M.C., Fukushige, S., Sakakibara, M., Joh, K., Mukai, T., Hori, K. Hum. Genet. (1987) [Pubmed]
  4. Chronically inflamed synovium from spondyloarthropathy and rheumatoid arthritis investigated by protein expression profiling followed by tandem mass spectrometry. Tilleman, K., Van Beneden, K., Dhondt, A., Hoffman, I., De Keyser, F., Veys, E., Elewaut, D., Deforce, D. Proteomics (2005) [Pubmed]
  5. Diagnosis of cancer by radioimmunoassay of muscle type aldolase. Asaka, M., Nagase, K., Shiraishi, T., Miyazaki, T. Gann = Gan. (1980) [Pubmed]
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