Gene Review:
LDHA - lactate dehydrogenase A
Homo sapiens
Synonyms:
Cell proliferation-inducing gene 19 protein, GSD11, HEL-S-133P, L-lactate dehydrogenase A chain, LDH muscle subunit, ...
Jurisic,
Bumbasirevic,
Konjevic,
Djuricic,
Spuzic,
Furukawa,
Adachi,
Fujisawa ,
Kambe,
Yamaguchi-Iwai,
Sasaki,
Kuwahara,
Ikehara,
Tokunaga,
Taketani,
Philibert,
Nelson,
Sandhu,
Crowe,
Coryell,
Schmidt,
Otto,
Niedmann,
Cepek,
Schröter,
Kretzschmar,
Poser,
Maekawa,
Inomata,
Sasaki,
Kaneko,
Ushiama,
Sugano,
Takayama,
Kanno,
- Rhabdomyosarcoma-associated locus and MYOD1 are syntenic but separate loci on the short arm of human chromosome 11. Scrable, H.J., Johnson, D.K., Rinchik, E.M., Cavenee, W.K. Proc. Natl. Acad. Sci. U.S.A. (1990)
- Involvement of PLAGL2 in activation of iron deficient- and hypoxia-induced gene expression in mouse cell lines. Furukawa, T., Adachi, Y., Fujisawa , J., Kambe, T., Yamaguchi-Iwai, Y., Sasaki, R., Kuwahara, J., Ikehara, S., Tokunaga, R., Taketani, S. Oncogene (2001)
- Electrophoretic variant of a lactate dehydrogenase isoenzyme and selective promoter methylation of the LDHA gene in a human retinoblastoma cell line. Maekawa, M., Inomata, M., Sasaki, M.S., Kaneko, A., Ushiama, M., Sugano, K., Takayama, J., Kanno, T. Clin. Chem. (2002)
- Molecular characterization of gene expression in human lactate dehydrogenase-A deficiency. Miyajima, H., Takahashi, Y., Suzuki, M., Shimizu, T., Kaneko, E. Neurology (1993)
- Hormonal regulation of lactate dehydrogenase-A through activation of protein kinase C pathways in MCF-7 breast cancer cells. Li, X., Qin, C., Burghardt, R., Safe, S. Biochem. Biophys. Res. Commun. (2004)
- Association of an exonic LDHA polymorphism with altered respiratory response in probands at high risk for panic disorder. Philibert, R.A., Nelson, J.J., Sandhu, H.K., Crowe, R.R., Coryell, W.H. Am. J. Med. Genet. B Neuropsychiatr. Genet. (2003)
- CSF lactate dehydrogenase activity in patients with Creutzfeldt-Jakob disease exceeds that in other dementias. Schmidt, H., Otto, M., Niedmann, P., Cepek, L., Schröter, A., Kretzschmar, H.A., Poser, S. Dementia and geriatric cognitive disorders. (2004)
- Differences in the chemical reactivity of individual molecules of an enzyme. Xue, Q., Yeung, E.S. Nature (1995)
- Direct current cardioversion. Effect on creatine kinase, lactic dehydrogenase and myocardial isoenzymes. Reiffel, J.A., Gambino, S.R., McCarthy, D.M., Leahey, E.B. JAMA (1978)
- A unique glucose-dependent apoptotic pathway induced by c-Myc. Shim, H., Chun, Y.S., Lewis, B.C., Dang, C.V. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Functional analysis of cis- and trans-regulatory elements of the lactate dehydrogenase A subunit promoter by in vitro transcription. Short, S., Short, M.L., Milkowski, D.M., Jungmann, R.A. J. Biol. Chem. (1991)
- Differential expression of two tomato lactate dehydrogenase genes in response to oxygen deficit. Germain, V., Raymond, P., Ricard, B. Plant Mol. Biol. (1997)
- Serum malondialdehyde-like material (MDA-LM) in acute myocardial infarction. Aznar, J., Santos, M.T., Valles, J., Sala, J. J. Clin. Pathol. (1983)
- Lactate dehydrogenase isoenzyme 1 in the diagnosis of myocardial infarction. Fogh-Andersen, N., Sørensen, P., Møller-Petersen, J., Ring, T. J. Clin. Chem. Clin. Biochem. (1982)
- Acute hemolysis associated with hepatitis A. Hara, K., Tagawa, K., Unuma, T. Gastroenterol. Jpn. (1985)
- Locus determining the human sperm-specific lactate dehydrogenase, LDHC, is syntenic with LDHA. Edwards, Y.H., Povey, S., LeVan, K.M., Driscoll, C.E., Millan, J.L., Goldberg, E. Dev. Genet. (1987)
- Mapping of human lactate dehydrogenase-A, -B, and -C genes and their related sequences: the gene for LDHC is located with that for LDHA on chromosome 11. Li, S.S., Luedemann, M., Sharief, F.S., Takano, T., Deaven, L.L. Cytogenet. Cell Genet. (1988)
- Regional localization of the sperm-specific lactate dehydrogenase, LDHC, gene on human chromosome 11. Edwards, Y., West, L., Van Heyningen, V., Cowell, J., Goldberg, E. Ann. Hum. Genet. (1989)
- Identification of breast cancer-restricted antigens by antibody screening of SKBR3 cDNA library using a preselected patient's serum. Forti, S., Scanlan, M.J., Invernizzi, A., Castiglioni, F., Pupa, S., Agresti, R., Fontanelli, R., Morelli, D., Old, L.J., Pupa, S.M., Ménard, S. Breast Cancer Res. Treat. (2002)
- Genotypic analysis of families with lactate dehydrogenase A (M) deficiency by selective DNA amplification. Maekawa, M., Sudo, K., Li, S.S., Kanno, T. Hum. Genet. (1991)
- Nucleotide sequences of the cDNA and an intronless pseudogene for human lactate dehydrogenase-A isozyme. Tsujibo, H., Tiano, H.F., Li, S.S. Eur. J. Biochem. (1985)
- Comparative gene mapping of man and Cebus capucinus: a study of 23 enzymatic markers. Créau-Goldberg, N., Cochet, C., Turleau, C., de Grouchy, J. Cytogenet. Cell Genet. (1981)
- A preliminary account of the properties of recombinant human Glyoxylate reductase (GRHPR), LDHA and LDHB with glyoxylate, and their potential roles in its metabolism. Mdluli, K., Booth, M.P., Brady, R.L., Rumsby, G. Biochim. Biophys. Acta (2005)
- Enzyme activities and isozyme patterns in human lung tumors. Balinsky, D., Greengard, O., Cayanis, E., Head, J.F. Cancer Res. (1984)
- Identification of LDH-ras p21 protein complex and expression of these genes in human ovarian cancer. Chow, S.N., Lin, J.K., Li, S.S., Chien, C.H. Gynecol. Oncol. (1997)
- Oncogenes in tumor metabolism, tumorigenesis, and apoptosis. Dang, C.V., Lewis, B.C., Dolde, C., Dang, G., Shim, H. J. Bioenerg. Biomembr. (1997)
- TNF-alpha induces changes in LDH isotype profile following triggering of apoptosis in PBL of non-Hodgkin's lymphomas. Jurisic, V., Bumbasirevic, V., Konjevic, G., Djuricic, B., Spuzic, I. Ann. Hematol. (2004)
- Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays. Kim, J.W., Zeller, K.I., Wang, Y., Jegga, A.G., Aronow, B.J., O'Donnell, K.A., Dang, C.V. Mol. Cell. Biol. (2004)
- Development and assignment of bovine-specific PCR systems for the Texas nomenclature marker genes and isolation of homologous BAC probes. Gautier, M., Laurent, P., Hayes, H., Eggen, A. Genet. Sel. Evol. (2001)
- A new gene mapping resource: interspecies hybrids between Père David's deer (Elaphurus davidianus) and red deer (Cervus elaphus). Tate, M.L., Mathias, H.C., Fennessy, P.F., Dodds, K.G., Penty, J.M., Hill, D.F. Genetics (1995)
- Analysis of genetic mutations in human lactate dehydrogenase-A(M) deficiency using DNA conformation polymorphism in combination with polyacrylamide gradient gel and silver staining. Maekawa, M., Sudo, K., Li, S.S., Kanno, T. Biochem. Biophys. Res. Commun. (1991)
- Increased glyceraldehyde-3-phosphate dehydrogenase expression in renal cell carcinoma identified by RNA-based, arbitrarily primed polymerase chain reaction. Vilà, M.R., Nicolás, A., Morote, J., de, I., Meseguer, A. Cancer (2000)