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Gene Review

Cyp2a3  -  cytochrome P450, family 2, subfamily a,...

Rattus norvegicus

Synonyms: CYPIIA3, Coumarin 7-hydroxylase, Cyp2a-3, Cyp2a3a, Cytochrome P450 2A3, ...
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High impact information on Cyp2a3a


Biological context of Cyp2a3a


Anatomical context of Cyp2a3a


Associations of Cyp2a3a with chemical compounds


  1. Comparative metabolism of N-nitrosopiperidine and N-nitrosopyrrolidine by rat liver and esophageal microsomes and cytochrome P450 2A3. Wong, H.L., Murphy, S.E., Wang, M., Hecht, S.S. Carcinogenesis (2003) [Pubmed]
  2. Clotrimazole-induced modulation of hepatic cytochrome P450 enzymes in Syrian and Chinese hamsters. Antignac, E., Fakuhara, M., Kimura, M., Ushio, F. Biochem. Pharmacol. (1992) [Pubmed]
  3. Comparative metabolism of the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol by rat cytochrome P450 2A3 and human cytochrome P450 2A13. Jalas, J.R., Ding, X., Murphy, S.E. Drug Metab. Dispos. (2003) [Pubmed]
  4. N-Nitrosobenzylmethylamine hydroxylation and coumarin 7-hydroxylation: catalysis by rat esophageal microsomes and cytochrome P450 2A3 and 2A6 enzymes. von Weymarn, L.B., Felicia, N.D., Ding, X., Murphy, S.E. Chem. Res. Toxicol. (1999) [Pubmed]
  5. Functional role of cytochrome p-450 2a3 in N-nitrosomethylbenzylamine metabolism in rat esophagus. Gopalakrishnan, R., Gupta, A., Carlton, P.S., Morse, M.A., Stoner, G.D. J. Toxicol. Environ. Health Part A (2002) [Pubmed]
  6. Coumarin metabolism by rat esophageal microsomes and cytochrome P450 2A3. von Weymarn, L.B., Murphy, S.E. Chem. Res. Toxicol. (2001) [Pubmed]
  7. Depentylation of the rat esophageal carcinogen, methyl-n-pentylnitrosamine, by microsomes from various human and rat tissues and by cytochrome P450 2A3. Chen, S.C., Zhou, L., Ding, X., Mirvish, S.S. Drug Metab. Dispos. (2001) [Pubmed]
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