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Chemical Compound Review

NPIP     1-nitrosopiperidine

Synonyms: NO-Pip, N-PIP, N-N-Pip, NSC-138, CCRIS 477, ...
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Disease relevance of N-NITROSOPIPERIDINE


High impact information on N-NITROSOPIPERIDINE


Biological context of N-NITROSOPIPERIDINE


Anatomical context of N-NITROSOPIPERIDINE


Associations of N-NITROSOPIPERIDINE with other chemical compounds


  1. Carcinogenicity of the isomeric, N-nitroso-delta3-and N-nitroso-delta2-piperidines in rats and the in vivo isomerization of the delta3-to the delta2-isomer. Kupper, R., Reuber, M.D., Blackwell, B.N., Lijinsky, W., Koepke, S.R., Michejda, C.J. Carcinogenesis (1980) [Pubmed]
  2. Activation of promutagenic N-nitrosomorpholine and other N-nitrosoalkylamines by near-ultraviolet irradiation in the presence of phosphates. Hayatsu, H., Shimada, H., Arimoto, S. Gann = Gan. (1984) [Pubmed]
  3. Measurements by filter elution of DNA single- and double-strand breaks in rat hepatocytes: effects of nitrosamines and gamma-irradiation. Bradley, M.O., Dysart, G., Fitzsimmons, K., Harbach, P., Lewin, J., Wolf, G. Cancer Res. (1982) [Pubmed]
  4. Comparative metabolism of N-nitrosopiperidine and N-nitrosopyrrolidine by rat liver and esophageal microsomes and cytochrome P450 2A3. Wong, H.L., Murphy, S.E., Wang, M., Hecht, S.S. Carcinogenesis (2003) [Pubmed]
  5. Fine structure of rat liver during chronic intoxication with two heterocyclic N-nitrosamines: N-nitrosopiperidine and the non-carcinogen, 2,2',6,6'-tetramethyl-N-nitrosopiperidine. Flaks, B., Challis, B.C. Carcinogenesis (1980) [Pubmed]
  6. Cytochrome P450 2A-catalyzed metabolic activation of structurally similar carcinogenic nitrosamines: N'-nitrosonornicotine enantiomers, N-nitrosopiperidine, and N-nitrosopyrrolidine. Wong, H.L., Murphy, S.E., Hecht, S.S. Chem. Res. Toxicol. (2005) [Pubmed]
  7. Biochemical studies of six nitrogen-containing heterocycles in rat tissues. Kitchin, K.T., Brown, J.L., Lijinsky, W. Biochem. Pharmacol. (1989) [Pubmed]
  8. Effects of N-nitrosopiperidine substitutions on mutagenicity in Drosophila melanogaster. Nix, C.E., Brewen, B., Wilkerson, R., Lijinsky, W., Epler, J.L. Mutat. Res. (1979) [Pubmed]
  9. Estimation of volatile N-nitrosamines in rubber nipples for babies' bottles. Havery, D.C., Fazio, T. Food Chem. Toxicol. (1982) [Pubmed]
  10. Effect of ascorbic acid and some reducing agents on N-nitrosopiperidine metabolism by liver microsomes. Nakamura, M., Horiguchi, Y., Kawabata, T. IARC Sci. Publ. (1984) [Pubmed]
  11. Fate and transport of N-nitrosamines under conditions simulating full-scale groundwater recharge operations. Drewes, J.E., Hoppe, C., Jennings, T. Water Environ. Res. (2006) [Pubmed]
  12. Alpha-hydroxylation in the metabolism of N-nitrosopiperidine by rat liver microsomes: formation of 5-hydroxypentanal. Leung, K.H., Park, K.K., Archer, M.C. Res. Commun. Chem. Pathol. Pharmacol. (1978) [Pubmed]
  13. A novel oxidative degradation of N-nitrosamine via electron transfer. Masui, M., Nose, K., Tanaka, A., Yamakawa, E., Ohmori, H. IARC Sci. Publ. (1982) [Pubmed]
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