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Chemical Compound Review

SureCN505449     7-pentoxyphenoxazin-3-one

Synonyms: AG-H-53966, P0928_SIGMA, CTK8D4973, STK299140, AR-1F3396, ...
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Disease relevance of Resorufin pentyl ether


High impact information on Resorufin pentyl ether


Biological context of Resorufin pentyl ether

  • Antibodies 1A and 3A inhibit both cytochrome P4501A1-dependent ethoxycoumarin hydroxylation activity and P4502B1-dependent pentoxyresorufin dealkylation activity, but the inhibition by 1A and 3A was not additive [8].
  • In this study, the kinetics of inactivation of CYP2B-dependent 7-pentoxyresorufin O-depentylation (PROD) and CYP1A-dependent 7-ethoxyresorufin O-deethylation (EROD) activities by enantiomers of N-(alpha-methylbenzyl)-1-aminobenzotriazole (alphaMB) were compared [9].
  • Furthermore, the different effects of both phosphatidylcholines on the Km and V for pentoxyresorufin not only suggest a role of phospholipids in the binding of the substrate to the active site of the cytochrome P-450 molecule, but also on the efficiency of electron transfer from NADPH-cytochrome reductase to cytochrome P-450 [10].
  • The time course for enzyme induction was monitored by measuring 7-ethoxyresorufin O-deethylase (EROD) and 7-pentoxyresorufin O-depentylase (PROD) activities on days 3, 7, 14, 21, and 28 [11].
  • A comparative study investigating the effects of various concentrations did not reveal, however, a clear correlation between the suppression of apoptosis and the induction of CYP2B-catalyzed 7-pentoxyresorufin O-dealkylase (PROD) activity [12].

Anatomical context of Resorufin pentyl ether


Associations of Resorufin pentyl ether with other chemical compounds


Gene context of Resorufin pentyl ether


Analytical, diagnostic and therapeutic context of Resorufin pentyl ether


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