Gene Review:
Cyp2a4 - cytochrome P450, family 2, subfamily a,...
Mus musculus
Synonyms:
AI893559, CYPIIA4, Cyp15a1, Cyp2a-4, Cytochrome P450 2A4, ...
- Overexpression of a cytochrome P-450 of the 2a family (Cyp2a-5) in chemically induced hepatomas from female mice. Jounaïdi, Y., Bonfils, C., Périn, F., Negishi, M., Lange, R. Eur. J. Biochem. (1994)
- Circadian expression of the steroid 15 alpha-hydroxylase (Cyp2a4) and coumarin 7-hydroxylase (Cyp2a5) genes in mouse liver is regulated by the PAR leucine zipper transcription factor DBP. Lavery, D.J., Lopez-Molina, L., Margueron, R., Fleury-Olela, F., Conquet, F., Schibler, U., Bonfils, C. Mol. Cell. Biol. (1999)
- Reciprocal regulation of sex-dependent expression of testosterone 15 alpha-hydroxylase (P-450(15 alpha)) in liver and kidney of male mice by androgen. Evidence for a single gene. Squires, E.J., Negishi, M. J. Biol. Chem. (1988)
- Sexual dimorphism of testosterone 15 alpha-hydroxylase mRNA levels in mouse liver. cDNA cloning and regulation. Burkhart, B.A., Harada, N., Negishi, M. J. Biol. Chem. (1985)
- Mouse liver testosterone 15 alpha-hydroxylase (cytochrome P-450(15) alpha). Purification, regioselectivity, stereospecificity, and sex-dependent expression. Harada, N., Negishi, M. J. Biol. Chem. (1984)
- Role of the peroxisome proliferator-activated receptor alpha in responses to diisononyl phthalate. Valles, E.G., Laughter, A.R., Dunn, C.S., Cannelle, S., Swanson, C.L., Cattley, R.C., Corton, J.C. Toxicology (2003)
- The inhibition of CYP enzymes in mouse and human liver by pilocarpine. Kimonen, T., Juvonen, R.O., Alhava, E., Pasanen, M. Br. J. Pharmacol. (1995)
- Transcriptional regulation by HNF-4 of the steroid 15alpha-hydroxylase P450 (Cyp2a-4) gene in mouse liver. Yokomori, N., Nishio, K., Aida, K., Negishi, M. J. Steroid Biochem. Mol. Biol. (1997)
- Genetic regulation of testosterone 15 alpha-hydroxylase (cytochrome P-450(15)alpha) in renal microsomes of female mice. Squires, E.J., Negishi, M. Biochemistry (1986)
- Cerium-induced strain-dependent increase in Cyp2a-4/5 (cytochrome P4502a-4/5) expression in the liver and kidneys of inbred mice. Salonpää, P., Iscan, M., Pasanen, M., Arvela, P., Pelkonen, O., Raunio, H. Biochem. Pharmacol. (1992)
- Effect of pyrazole, cobalt and phenobarbital on mouse liver cytochrome P-450 2a-4/5 (Cyp2a-4/5) expression. Hahnemann, B., Salonpää, P., Pasanen, M., Mäenpää, J., Honkakoski, P., Juvonen, R., Lang, M.A., Pelkonen, O., Raunio, H. Biochem. J. (1992)
- Lack of the steroid 15 alpha-hydroxylase gene (Cyp2a-4) in wild mouse strain Mus spretus: rapid evolution of the P450 gene superfamily. Aida, K., Moore, R., Negishi, M. Genomics (1994)
- Gender-specific induction of cytochrome P450s in nonylphenol-treated FVB/NJ mice. Hernandez, J.P., Chapman, L.M., Kretschmer, X.C., Baldwin, W.S. Toxicol. Appl. Pharmacol. (2006)
- Developmental action of estrogen receptor-alpha feminizes the growth hormone-Stat5b pathway and expression of Cyp2a4 and Cyp2d9 genes in mouse liver. Sueyoshi, T., Yokomori, N., Korach, K.S., Negishi, M. Mol. Pharmacol. (1999)
- Tissue-specific regulation of cytochrome P-450 dependent testosterone 15 alpha-hydroxylase. Squires, E.J., Negishi, M. Can. J. Physiol. Pharmacol. (1990)