Gene Review:
ADAM2 - ADAM metallopeptidase domain 2
Homo sapiens
Synonyms:
ADAM 2, CRYN1, CRYN2, CT15, Cancer/testis antigen 15, ...
- A novel metalloprotease/disintegrin-like gene at 17q21.3 is somatically rearranged in two primary breast cancers. Emi, M., Katagiri, T., Harada, Y., Saito, H., Inazawa, J., Ito, I., Kasumi, F., Nakamura, Y. Nat. Genet. (1993)
- Role of the integrin-associated protein CD9 in binding between sperm ADAM 2 and the egg integrin alpha6beta1: implications for murine fertilization. Chen, M.S., Tung, K.S., Coonrod, S.A., Takahashi, Y., Bigler, D., Chang, A., Yamashita, Y., Kincade, P.W., Herr, J.C., White, J.M. Proc. Natl. Acad. Sci. U.S.A. (1999)
- The precursor region of a protein active in sperm-egg fusion contains a metalloprotease and a disintegrin domain: structural, functional, and evolutionary implications. Wolfsberg, T.G., Bazan, J.F., Blobel, C.P., Myles, D.G., Primakoff, P., White, J.M. Proc. Natl. Acad. Sci. U.S.A. (1993)
- Fertilin beta and other ADAMs as integrin ligands: insights into cell adhesion and fertilization. Evans, J.P. Bioessays (2001)
- Functional classification of ADAMs based on a conserved motif for binding to integrin alpha 9beta 1: implications for sperm-egg binding and other cell interactions. Eto, K., Huet, C., Tarui, T., Kupriyanov, S., Liu, H.Z., Puzon-McLaughlin, W., Zhang, X.P., Sheppard, D., Engvall, E., Takada, Y. J. Biol. Chem. (2002)
- The ADAM-integrin-tetraspanin complex in fetal and postnatal testicular cords. Tres, L.L., Kierszenbaum, A.L. Birth Defects Res. C Embryo Today (2005)
- Identification and characterization of ADAM32 with testis-predominant gene expression. Choi, I., Woo, J.M., Hong, S., Jung, Y.K., Kim, d.o. .H., Cho, C. Gene (2003)
- Apexin, an acrosomal pentaxin. Reid, M.S., Blobel, C.P. J. Biol. Chem. (1994)
- Differential localization of ADAM1a and ADAM1b in the endoplasmic reticulum of testicular germ cells and on the surface of epididymal sperm. Kim, E., Nishimura, H., Baba, T. Biochem. Biophys. Res. Commun. (2003)
- Membrane interaction of synthetic peptides related to the putative fusogenic region of PH-30 alpha, a protein in sperm-egg fusion. Niidome, T., Kimura, M., Chiba, T., Ohmori, N., Mihara, H., Aoyagi, H. J. Pept. Res. (1997)
- Mammalian fertilization as a biological machine: a working model for adhesion and fusion of sperm and oocyte. Green, D.P. Hum. Reprod. (1993)
- Purification, cloning, and molecular characterization of a high molecular weight hemorrhagic metalloprotease, jararhagin, from Bothrops jararaca venom. Insights into the disintegrin gene family. Paine, M.J., Desmond, H.P., Theakston, R.D., Crampton, J.M. J. Biol. Chem. (1992)
- Sperm antigens and immunocontraception. Kerr, L.E. Reprod. Fertil. Dev. (1995)
- Molecular cloning of the human fertilin beta subunit. Gupta, S.K., Alves, K., Palladino, L.O., Mark, G.E., Hollis, G.F. Biochem. Biophys. Res. Commun. (1996)