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Gene Review:

OR4G1P - olfactory receptor, family 4, subfamily G,...

Homo sapiens

Synonyms: OLB, OR4G8P

Miller, R.F. et al., Ravini, M. et al., Feuerstein, M. et al., Baldwin, M.L. et al., Lahiri, S. et al.

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Disease relevance of OR4G1P

We retrospectively evaluated: 1) the strategy of the bioptic approach in the Milan Sarcoid Clinic in the years 1992-1995 (201 patients) versus 1988-1991 (197 patients); and 2) data from 65 VTLB procedures in the years 1992-1995 versus 68 OLB procedures in the years 1988-1991 performed in patients with diffuse lung disease [1].
BACKGROUND: Occupational low back pain (OLBP) is widespread in industrialized societies [2].
METHODS--A retrospective review of OLB in HIV positive patients admitted to a specialist inpatient unit with acute respiratory symptoms was carried out in order to define clinical indications, diagnostic yield, impact on management, complications and outcome [3].
The results of OLB were in Group A 5 patients had non specific interstitial pneumonitis (NIP), 1 also had Kaposi's sarcoma, 4 had pneumocystis pneumonia (1 also had bronchiolitis obliterans organising pneumonia [BOOP]), 3 had Kaposi's sarcoma and 1 had BOOP and emphysema, 1 had pulmonary infarction and no infection and 1 had normal lung tissue [3].

Psychiatry related information on OR4G1P

METHODS: The present investigation was a case-control study (n = 421) of demographic, health behavior, ergonomic, workplace and individual psychosocial factors hypothesized to be associated with lost time in young, full-time employees (i.e., soldiers) with OLBP [4].

High impact information on OR4G1P

VTLB compares favourably with OLB as there is less need for analgesia (7.5+/-7.5 versus 17.5+/-8.0 methadone mg i.m.: p<0.001), lower blood loss (61+/-58 versus 156+/-84 mL in the first postoperative day: p<0.001), and shorter postoperative stay (4.7+/-1.6 versus 5.7+/-1.4 days: p<0.001) [1].
RESULTS: The current literature suggests that chiropractors and physicians provide equally effective care for OLBP but that chiropractic patients are more satisfied with their care [5].

Analytical, diagnostic and therapeutic context of OR4G1P

It was found that the use of OLB (17-9%), mediastinoscopy (15-5%), and scalene node biopsy (20-7%) decreased, whereas transbronchial biopsy (TBB) increased (11-17%) [1].
BACKGROUND--Open lung biopsy (OLB) is rarely necessary for investigation of HIV positive patients with acute respiratory episodes because of the high yield from fibreoptic bronchoscopy with bronchoalveolar lavage (BAL) [3].

References

Changing strategies of lung biopsies in diffuse lung diseases: the impact of video-assisted thoracoscopy. Ravini, M., Ferraro, G., Barbieri, B., Colombo, P., Rizzato, G. Eur. Respir. J. (1998) [Pubmed]
Estimation of net-costs for prevention of occupational low back pain: three case studies from the US. Lahiri, S., Gold, J., Levenstein, C. Am. J. Ind. Med. (2005) [Pubmed]
Open lung biopsy for investigation of acute respiratory episodes in patients with HIV infection and AIDS. Miller, R.F., Pugsley, W.B., Griffiths, M.H. Genitourinary medicine. (1995) [Pubmed]
Working with low back pain: workplace and individual psychosocial determinants of limited duty and lost time. Feuerstein, M., Berkowitz, S.M., Haufler, A.J., Lopez, M.S., Huang, G.D. Am. J. Ind. Med. (2001) [Pubmed]
Cost-effectiveness studies of medical and chiropractic care for occupational low back pain. a critical review of the literature. Baldwin, M.L., Côté, P., Frank, J.W., Johnson, W.G. The spine journal : official journal of the North American Spine Society. (2001) [Pubmed]

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