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MeSH Review

Bronchoalveolar Lavage

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Disease relevance of Bronchoalveolar Lavage


Psychiatry related information on Bronchoalveolar Lavage


High impact information on Bronchoalveolar Lavage


Chemical compound and disease context of Bronchoalveolar Lavage


Biological context of Bronchoalveolar Lavage


Anatomical context of Bronchoalveolar Lavage


Associations of Bronchoalveolar Lavage with chemical compounds


Gene context of Bronchoalveolar Lavage

  • Furthermore, IL-10-/- outbred mice exhibited exaggerated airway inflammation and heightened levels of IL-5 and IFN-gamma in bronchoalveolar lavage (BAL) fluids [30].
  • By contrast, steroid-sensitive (SS) asthmatics respond well to glucocorticoids, and this is accompanied by a decrease in the numbers of bronchoalveolar lavage (BAL) messenger RNA+ (mRNA+) cells expressing IL-4 and IL-5, and an increase in interferon gamma (IFN-gamma) transcripts [31].
  • MCP-4 mRNA was found in cells collected in bronchoalveolar lavage of asthmatic and nonasthmatic subjects and was prominently expressed in human lung and heart [32].
  • Recombinant human IL-2 (10(6) U IV per rat, n = 6) elevated lung water, myeloperoxidase activity, and protein accumulation in bronchoalveolar lavage fluid and induced tissue hypoxia [33].
  • Trimeric SP-A1(DeltaAVC,C6S) was compared with supratrimeric SP-A1, which is structurally and functionally comparable to the octadecameric protein isolated from human lung lavages [34].

Analytical, diagnostic and therapeutic context of Bronchoalveolar Lavage


  1. Leukotriene C4 and D4 in neonates with hypoxemia and pulmonary hypertension. Stenmark, K.R., James, S.L., Voelkel, N.F., Toews, W.H., Reeves, J.T., Murphy, R.C. N. Engl. J. Med. (1983) [Pubmed]
  2. Antibody to very late activation antigen 4 prevents antigen-induced bronchial hyperreactivity and cellular infiltration in the guinea pig airways. Pretolani, M., Ruffié, C., Lapa e Silva, J.R., Joseph, D., Lobb, R.R., Vargaftig, B.B. J. Exp. Med. (1994) [Pubmed]
  3. Evidence of lung surfactant abnormality in respiratory failure. Study of bronchoalveolar lavage phospholipids, surface activity, phospholipase activity, and plasma myoinositol. Hallman, M., Spragg, R., Harrell, J.H., Moser, K.M., Gluck, L. J. Clin. Invest. (1982) [Pubmed]
  4. Detection of K-ras oncogene mutations in bronchoalveolar lavage fluid for lung cancer diagnosis. Mills, N.E., Fishman, C.L., Scholes, J., Anderson, S.E., Rom, W.N., Jacobson, D.R. J. Natl. Cancer Inst. (1995) [Pubmed]
  5. Elevated plasma and lung endothelial selectin levels in patients with acute respiratory distress syndrome and a history of chronic alcohol abuse. Burnham, E.L., Moss, M., Harris, F., Brown, L.A. Crit. Care Med. (2004) [Pubmed]
  6. Twenty-five-year follow-up of a patient treated with lung lavage for pulmonary alveolar proteinosis. Green, D., Criner, G.J. N. Engl. J. Med. (1987) [Pubmed]
  7. Pulmonary oxygen toxicity. Early reversible changes in human alveolar structures induced by hyperoxia. Davis, W.B., Rennard, S.I., Bitterman, P.B., Crystal, R.G. N. Engl. J. Med. (1983) [Pubmed]
  8. Carcinoembryonic antigen in bronchoalveolar lavage fluid. Lemarie, C., Lavandier, M., Renoux, M., Renoux, G. N. Engl. J. Med. (1980) [Pubmed]
  9. Effector CD8+ T cells mediate inflammation and airway hyper-responsiveness. Miyahara, N., Swanson, B.J., Takeda, K., Taube, C., Miyahara, S., Kodama, T., Dakhama, A., Ott, V.L., Gelfand, E.W. Nat. Med. (2004) [Pubmed]
  10. Functional alpha 1-protease inhibitor in the lower respiratory tract of cigarette smokers is not decreased. Stone, P.J., Calore, J.D., McGowan, S.E., Bernardo, J., Snider, G.L., Franzblau, C. Science (1983) [Pubmed]
  11. The in vivo transfer of antigen-induced airway reactions by bronchial lumen cells. Patterson, R., Suszko, I.M., Harris, K.E. J. Clin. Invest. (1978) [Pubmed]
  12. Serum angiotensin-converting enzyme and bronchoalveolar lavage in sarcoidosis. Stanislas-Leguern, G., Marsac, J., Arnoux, A., Lecossier, D. Lancet (1979) [Pubmed]
  13. Pulmonary disposition of cortisol. Braude, A.C., Rebuck, A.S. Ann. Intern. Med. (1982) [Pubmed]
  14. A tuberculostearic acid assay in the diagnosis of sputum smear-negative pulmonary tuberculosis. A prospective study of bronchoscopic aspirate and lavage specimens. Pang, J.A., Chan, H.S., Chan, C.Y., Cheung, S.W., French, G.L. Ann. Intern. Med. (1989) [Pubmed]
  15. Proapoptotic Bid is required for pulmonary fibrosis. Budinger, G.R., Mutlu, G.M., Eisenbart, J., Fuller, A.C., Bellmeyer, A.A., Baker, C.M., Wilson, M., Ridge, K., Barrett, T.A., Lee, V.Y., Chandel, N.S. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
  16. Cigarette smoke inhalation decreases alpha 1-antitrypsin activity in rat lung. Janoff, A., Carp, H., Lee, D.K., Drew, R.T. Science (1979) [Pubmed]
  17. Hydrogen peroxide release by alveolar macrophages from sarcoid patients and by alveolar macrophages from normals after exposure to recombinant interferons alpha A, beta, and gamma and 1,25-dihydroxyvitamin D3. Fels, A.O., Nathan, C.F., Cohn, Z.A. J. Clin. Invest. (1987) [Pubmed]
  18. An experimental human model of metal fume fever. Blanc, P., Wong, H., Bernstein, M.S., Boushey, H.A. Ann. Intern. Med. (1991) [Pubmed]
  19. Regulatory effects of interleukin-6 in immunoglobulin G immune-complex-induced lung injury. Shanley, T.P., Foreback, J.L., Remick, D.G., Ulich, T.R., Kunkel, S.L., Ward, P.A. Am. J. Pathol. (1997) [Pubmed]
  20. alphadbeta2 integrin is expressed on human eosinophils and functions as an alternative ligand for vascular cell adhesion molecule 1 (VCAM-1). Grayson, M.H., Van der Vieren, M., Sterbinsky, S.A., Michael Gallatin, W., Hoffman, P.A., Staunton, D.E., Bochner, B.S. J. Exp. Med. (1998) [Pubmed]
  21. Clearance of influenza virus respiratory infection in mice lacking class I major histocompatibility complex-restricted CD8+ T cells. Eichelberger, M., Allan, W., Zijlstra, M., Jaenisch, R., Doherty, P.C. J. Exp. Med. (1991) [Pubmed]
  22. Oxidative regulation of neutrophil elastase-alpha-1-proteinase inhibitor interactions. Ossanna, P.J., Test, S.T., Matheson, N.R., Regiani, S., Weiss, S.J. J. Clin. Invest. (1986) [Pubmed]
  23. Thrombin receptor expression in normal and atherosclerotic human arteries. Nelken, N.A., Soifer, S.J., O'Keefe, J., Vu, T.K., Charo, I.F., Coughlin, S.R. J. Clin. Invest. (1992) [Pubmed]
  24. Production of fibronectin by the human alveolar macrophage: mechanism for the recruitment of fibroblasts to sites of tissue injury in interstitial lung diseases. Rennard, S.I., Hunninghake, G.W., Bitterman, P.B., Crystal, R.G. Proc. Natl. Acad. Sci. U.S.A. (1981) [Pubmed]
  25. The interaction in vitro of Pneumocystis carinii with macrophages and L-cells. Masur, H., Jones, T.C. J. Exp. Med. (1978) [Pubmed]
  26. Uteroglobin represses allergen-induced inflammatory response by blocking PGD2 receptor-mediated functions. Mandal, A.K., Zhang, Z., Ray, R., Choi, M.S., Chowdhury, B., Pattabiraman, N., Mukherjee, A.B. J. Exp. Med. (2004) [Pubmed]
  27. Direct evidence of a role for mast cells in the pathogenesis of antigen-induced bronchoconstriction. Casale, T.B., Wood, D., Richerson, H.B., Zehr, B., Zavala, D., Hunninghake, G.W. J. Clin. Invest. (1987) [Pubmed]
  28. Perception of bronchial obstruction in asthmatic patients. Relationship with bronchial eosinophilic inflammation and epithelial damage and effect of corticosteroid treatment. Roisman, G.L., Peiffer, C., Lacronique, J.G., Le Cae, A., Dusser, D.J. J. Clin. Invest. (1995) [Pubmed]
  29. Intraamniotic interleukin-1 accelerates surfactant protein synthesis in fetal rabbits and improves lung stability after premature birth. Bry, K., Lappalainen, U., Hallman, M. J. Clin. Invest. (1997) [Pubmed]
  30. Interleukin-10 is a natural suppressor of cytokine production and inflammation in a murine model of allergic bronchopulmonary aspergillosis. Grünig, G., Corry, D.B., Leach, M.W., Seymour, B.W., Kurup, V.P., Rennick, D.M. J. Exp. Med. (1997) [Pubmed]
  31. Dysregulation of interleukin 4, interleukin 5, and interferon gamma gene expression in steroid-resistant asthma. Leung, D.Y., Martin, R.J., Szefler, S.J., Sher, E.R., Ying, S., Kay, A.B., Hamid, Q. J. Exp. Med. (1995) [Pubmed]
  32. Production of the novel C-C chemokine MCP-4 by airway cells and comparison of its biological activity to other C-C chemokines. Stellato, C., Collins, P., Ponath, P.D., Soler, D., Newman, W., La Rosa, G., Li, H., White, J., Schwiebert, L.M., Bickel, C., Liu, M., Bochner, B.S., Williams, T., Schleimer, R.P. J. Clin. Invest. (1997) [Pubmed]
  33. Locally produced tumor necrosis factor-alpha mediates interleukin-2-induced lung injury. Rabinovici, R., Feuerstein, G., Abdullah, F., Whiteford, M., Borboroglu, P., Sheikh, E., Phillip, D.R., Ovadia, P., Bobroski, L., Bagasra, O., Neville, L.F. Circ. Res. (1996) [Pubmed]
  34. Role of the degree of oligomerization in the structure and function of human surfactant protein A. Sánchez-Barbero, F., Strassner, J., García-Cañero, R., Steinhilber, W., Casals, C. J. Biol. Chem. (2005) [Pubmed]
  35. Role of the scavenger receptor MARCO in alveolar macrophage binding of unopsonized environmental particles. Palecanda, A., Paulauskis, J., Al-Mutairi, E., Imrich, A., Qin, G., Suzuki, H., Kodama, T., Tryggvason, K., Koziel, H., Kobzik, L. J. Exp. Med. (1999) [Pubmed]
  36. Increased levels of bombesin-like peptides in the lower respiratory tract of asymptomatic cigarette smokers. Aguayo, S.M., Kane, M.A., King, T.E., Schwarz, M.I., Grauer, L., Miller, Y.E. J. Clin. Invest. (1989) [Pubmed]
  37. Fibronectin fragments containing the RGDS cell-binding domain mediate monocyte migration into the rabbit lung. A potential mechanism for C5 fragment-induced monocyte lung accumulation. Doherty, D.E., Henson, P.M., Clark, R.A. J. Clin. Invest. (1990) [Pubmed]
  38. Critical role for the chemokine MCP-1/CCR2 in the pathogenesis of bronchiolitis obliterans syndrome. Belperio, J.A., Keane, M.P., Burdick, M.D., Lynch, J.P., Xue, Y.Y., Berlin, A., Ross, D.J., Kunkel, S.L., Charo, I.F., Strieter, R.M. J. Clin. Invest. (2001) [Pubmed]
  39. Eosinophils express interleukin 5 and granulocyte macrophage-colony-stimulating factor mRNA at sites of allergic inflammation in asthmatics. Broide, D.H., Paine, M.M., Firestein, G.S. J. Clin. Invest. (1992) [Pubmed]
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