Gene Review:
sca - scabrous
Drosophila melanogaster
Synonyms:
AAA28880, AAF58455, CG17579, Dmel\CG17579, FBpp0086968, ...
- Scabrous complexes with Notch to mediate boundary formation. Powell, P.A., Wesley, C., Spencer, S., Cagan, R.L. Nature (2001)
- Isolation and expression of scabrous, a gene regulating neurogenesis in Drosophila. Mlodzik, M., Baker, N.E., Rubin, G.M. Genes Dev. (1990)
- Scabrous and Gp150 are endosomal proteins that regulate Notch activity. Li, Y., Fetchko, M., Lai, Z.C., Baker, N.E. Development (2003)
- Homeotic control in Drosophila; the scabrous gene is an in vivo target of Ultrabithorax proteins. Graba, Y., Aragnol, D., Laurenti, P., Garzino, V., Charmot, D., Berenger, H., Pradel, J. EMBO J. (1992)
- Egfr signalling defines a protective function for ommatidial orientation in the Drosophila eye. Brown, K.E., Freeman, M. Development (2003)
- Linkage disequilibrium mapping of molecular polymorphisms at the scabrous locus associated with naturally occurring variation in bristle number in Drosophila melanogaster. Lyman, R.F., Lai, C., MacKay, T.F. Genet. Res. (1999)
- scabrous modifies epithelial cell adhesion and extends the range of lateral signalling during development of the spaced bristle pattern in Drosophila. Renaud, O., Simpson, P. Dev. Biol. (2001)
- The scabrous gene encodes a secreted glycoprotein dimer and regulates proneural development in Drosophila eyes. Lee, E.C., Hu, X., Yu, S.Y., Baker, N.E. Mol. Cell. Biol. (1996)
- The scabrous protein can act as an extracellular antagonist of notch signaling in the Drosophila wing. Lee, E.C., Yu, S.Y., Baker, N.E. Curr. Biol. (2000)
- A primary role for the epidermal growth factor receptor in ommatidial spacing in the Drosophila eye. Baonza, A., Casci, T., Freeman, M. Curr. Biol. (2001)