Gene Review:
rap - retina aberrant in pattern
Drosophila melanogaster
Synonyms:
APC/C[Fzr/Cdh1], CDH1, CG3000, Cdh1, Cdh1/Fzr, ...
- Drosophila fizzy-related down-regulates mitotic cyclins and is required for cell proliferation arrest and entry into endocycles. Sigrist, S.J., Lehner, C.F. Cell (1997)
- A novel motif governs APC-dependent degradation of Drosophila ORC1 in vivo. Araki, M., Yu, H., Asano, M. Genes Dev. (2005)
- The roles of Fzy/Cdc20 and Fzr/Cdh1 in regulating the destruction of cyclin B in space and time. Raff, J.W., Jeffers, K., Huang, J.Y. J. Cell Biol. (2002)
- Notch-dependent Fizzy-related/Hec1/Cdh1 expression is required for the mitotic-to-endocycle transition in Drosophila follicle cells. Schaeffer, V., Althauser, C., Shcherbata, H.R., Deng, W.M., Ruohola-Baker, H. Curr. Biol. (2004)
- The mitotic-to-endocycle switch in Drosophila follicle cells is executed by Notch-dependent regulation of G1/S, G2/M and M/G1 cell-cycle transitions. Shcherbata, H.R., Althauser, C., Findley, S.D., Ruohola-Baker, H. Development (2004)
- Notch-dependent downregulation of the homeodomain gene cut is required for the mitotic cycle/endocycle switch and cell differentiation in Drosophila follicle cells. Sun, J., Deng, W.M. Development (2005)
- Rca1 inhibits APC-Cdh1(Fzr) and is required to prevent cyclin degradation in G2. Grosskortenhaus, R., Sprenger, F. Dev. Cell (2002)
- rap gene encodes Fizzy-related protein (Fzr) and regulates cell proliferation and pattern formation in the developing Drosophila eye-antennal disc. Pimentel, A.C., Venkatesh, T.R. Dev. Biol. (2005)
- Regulation of the embryonic cell proliferation by Drosophila cyclin D and cyclin E complexes. Lehner, C.F., Jacobs, H.W., Sauer, K., Meyer, C.A. Novartis Found. Symp. (2001)