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Gene Review

PPP1CC  -  protein phosphatase 1, catalytic subunit,...

Homo sapiens

Synonyms: PP-1G, PP1C, PP1gamma, PPP1G, Protein phosphatase 1C catalytic subunit, ...
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High impact information on PPP1CC


Biological context of PPP1CC


Anatomical context of PPP1CC


Analytical, diagnostic and therapeutic context of PPP1CC

  • In rabbit muscle, analyzed by Western blot, the glycogen-bound protein phosphatase-1 (PP-1G) is composed of a 37-kilodalton (kDa) catalytic subunit complexed to a 160-kDa glycogen-binding subunit (G-subunit) responsible for the interaction of PP-1G with glycogen [5].


  1. The structure and regulation of protein phosphatases. Cohen, P. Annu. Rev. Biochem. (1989) [Pubmed]
  2. Protein phosphatase-1 and insulin action. Ragolia, L., Begum, N. Mol. Cell. Biochem. (1998) [Pubmed]
  3. Assignment of the gene encoding type 1 gamma protein phosphatase catalytic subunit (PPP1CC) on human, rat, and mouse chromosomes. Saadat, M., Nomoto, K., Mizuno, Y., Kikuchi, K., Yoshida, M.C. Jpn. J. Hum. Genet. (1996) [Pubmed]
  4. Sequence of human protein serine/threonine phosphatase 1 gamma and localization of the gene (PPP1CC) encoding it to chromosome bands 12q24.1-q24.2. Barker, H.M., Craig, S.P., Spurr, N.K., Cohen, P.T. Biochim. Biophys. Acta (1993) [Pubmed]
  5. Immunoreactive glycogen-binding subunit of protein phosphatase-1 in human skeletal muscle. Nyomba, B.L., Mott, D.M. J. Clin. Endocrinol. Metab. (1994) [Pubmed]
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