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Parva  -  parvin, alpha

Rattus norvegicus

Synonyms: Actopaxin, Actp, Alpha-parvin
 
 
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Disease relevance of Parva

  • Immunity to East Coast fever in cattle induced by a polypeptide fragment of the major surface coat protein of Theileria parva sporozoites [1].
  • When cercariae were kept in the same bath as the freshwater fish, Pseudorasbora parva, which were free from trematode infections, parasites encysted only in the gills of fishes at day 4 postinfection (PI) [2].
  • Pseudorasbora parva were collected at an endemic river of clonorchiasis and were used for irradiation of the fluke in three schemes [3].
 

High impact information on Parva

 

Biological context of Parva

 

Anatomical context of Parva

  • Characterisation of the gene encoding a candidate vaccine antigen of Theileria parva sporozoites [7].
  • A different monoclonal antibody, SPA-820, which also recognises members of the hsp 70 kDa family, bound to proteins isolated from Theileria parva Muguga transformed lymphoblastoid cell lines (TpM) [8].
 

Analytical, diagnostic and therapeutic context of Parva

References

  1. Immunity to East Coast fever in cattle induced by a polypeptide fragment of the major surface coat protein of Theileria parva sporozoites. Bishop, R., Nene, V., Staeyert, J., Rowlands, J., Nyanjui, J., Osaso, J., Morzaria, S., Musoke, A. Vaccine (2003) [Pubmed]
  2. Morphological observations of Echinochasmus japonicus cercariae and the in vitro maintenance of its life cycle from cercariae to adults. Choi, M.H., Kim, S.H., Chung, J.H., Jang, H.J., Eom, J.H., Chung, B.S., Sohn, W.M., Chai, J.Y., Hong, S.T. J. Parasitol. (2006) [Pubmed]
  3. The effects of gamma irradiation on the survival and development of Clonorchis sinensis metacercariae. Lee, S.H., Park, Y.H., Sohn, W.M., Hong, S.T., Chai, J.Y. Kisaengchunghak Chapchi (1989) [Pubmed]
  4. Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion. Nikolopoulos, S.N., Turner, C.E. J. Cell Biol. (2000) [Pubmed]
  5. Actopaxin interacts with TESK1 to regulate cell spreading on fibronectin. LaLonde, D.P., Brown, M.C., Bouverat, B.P., Turner, C.E. J. Biol. Chem. (2005) [Pubmed]
  6. Actopaxin is phosphorylated during mitosis and is a substrate for cyclin B1/cdc2 kinase. Curtis, M., Nikolopoulos, S.N., Turner, C.E. Biochem. J. (2002) [Pubmed]
  7. Characterisation of the gene encoding a candidate vaccine antigen of Theileria parva sporozoites. Nene, V., Iams, K.P., Gobright, E., Musoke, A.J. Mol. Biochem. Parasitol. (1992) [Pubmed]
  8. A rapid, single-step purification method for immunogenic members of the hsp 70 family: validation and application. Nandan, D., Daubenberger, C., Mpimbaza, G., Pearson, T.W. J. Immunol. Methods (1994) [Pubmed]
 
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