Gene Review:
GAL3ST2 - galactose-3-O-sulfotransferase 2
Homo sapiens
Synonyms:
Beta-galactose-3-O-sulfotransferase 2, GAL3ST-2, GP3ST, Gal-beta-1, 3-GalNAc 3'-sulfotransferase 2, Gal3ST-2, ...
- Gal3ST-2 involved in tumor metastasis process by regulation of adhesion ability to selectins and expression of integrins. Shi, B.Z., Hu, P., Geng, F., He, P.J., Wu, X.Z. Biochem. Biophys. Res. Commun. (2005)
- Down-regulation of Gal 3-O-sulfotransferase-2 (Gal3ST-2) expression in human colonic non-mucinous adenocarcinoma. Seko, A., Nagata, K., Yonezawa, S., Yamashita, K. Jpn. J. Cancer Res. (2002)
- Identification of physiologically relevant substrates for cloned Gal: 3-O-sulfotransferases (Gal3STs): distinct high affinity of Gal3ST-2 and LS180 sulfotransferase for the globo H backbone, Gal3ST-3 for N-glycan multiterminal Galbeta1, 4GlcNAcbeta units and 6-sulfoGalbeta1, 4GlcNAcbeta, and Gal3ST-4 for the mucin core-2 trisaccharide. Chandrasekaran, E.V., Lakhaman, S.S., Chawda, R., Piskorz, C.F., Neelamegham, S., Matta, K.L. J. Biol. Chem. (2004)
- Molecular cloning and characterization of a human beta-Gal-3'-sulfotransferase that acts on both type 1 and type 2 (Gal beta 1-3/1-4GlcNAc-R) oligosaccharides. Honke, K., Tsuda, M., Koyota, S., Wada, Y., Iida-Tanaka, N., Ishizuka, I., Nakayama, J., Taniguchi, N. J. Biol. Chem. (2001)
- A novel human Gal-3-O-sulfotransferase: molecular cloning, characterization, and its implications in biosynthesis of (SO(4)-3)Galbeta1-4(Fucalpha1-3)GlcNAc. El-Fasakhany, F.M., Uchimura, K., Kannagi, R., Muramatsu, T. J. Biol. Chem. (2001)
- A remodeling system of the 3'-sulfo-Lewis a and 3'-sulfo-Lewis x epitopes. Ikeda, N., Eguchi, H., Nishihara, S., Narimatsu, H., Kannagi, R., Irimura, T., Ohta, M., Matsuda, H., Taniguchi, N., Honke, K. J. Biol. Chem. (2001)
- Molecular cloning and expression of a novel human beta-Gal-3-O-sulfotransferase that acts preferentially on N-acetyllactosamine in N- and O-glycans. Suzuki, A., Hiraoka, N., Suzuki, M., Angata, K., Misra, A.K., McAuliffe, J., Hindsgaul, O., Fukuda, M. J. Biol. Chem. (2001)
- In vitro sulfation of N-acetyllactosaminide by soluble recombinant human beta-Gal-3'-sulfotransferase. Greimel, P., Jabs, S., Storch, S., Cherif, S., Honke, K., Braulke, T., Thiem, J. Carbohydr. Res. (2006)