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Gene Review

MEK1  -  mitogen-activated protein kinase kinase 1

Arabidopsis thaliana

Synonyms: ATMEK1, F20B18.180, F20B18_180, MAP kinase/ ERK kinase 1, MITOGEN ACTIVATED PROTEIN KINASE KINASE, ...
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Disease relevance of MEK1


High impact information on MEK1


Associations of MEK1 with chemical compounds


Enzymatic interactions of MEK1


Regulatory relationships of MEK1


Other interactions of MEK1


  1. Activation of AtMEK1, an Arabidopsis mitogen-activated protein kinase kinase, in vitro and in vivo: analysis of active mutants expressed in E. coli and generation of the active form in stress response in seedlings. Matsuoka, D., Nanmori, T., Sato, K., Fukami, Y., Kikkawa, U., Yasuda, T. Plant J. (2002) [Pubmed]
  2. Arabidopsis FUSCA5 encodes a novel phosphoprotein that is a component of the COP9 complex. Karniol, B., Malec, P., Chamovitz, D.A. Plant Cell (1999) [Pubmed]
  3. The Arabidopsis MAP kinase kinase MKK1 participates in defence responses to the bacterial elicitor flagellin. M??sz??ros, T., Helfer, A., Hatzimasoura, E., Magyar, Z., Serazetdinova, L., Rios, G., Bard??czy, V., Teige, M., Koncz, C., Peck, S., B??gre, L. Plant J. (2006) [Pubmed]
  4. Overexpression of a kinase-deficient form of the EDR1 gene enhances powdery mildew resistance and ethylene-induced senescence in Arabidopsis. Tang, D., Innes, R.W. Plant J. (2002) [Pubmed]
  5. ATMPK4, an Arabidopsis homolog of mitogen-activated protein kinase, is activated in vitro by AtMEK1 through threonine phosphorylation. Huang, Y., Li, H., Gupta, R., Morris, P.C., Luan, S., Kieber, J.J. Plant Physiol. (2000) [Pubmed]
  6. Activation of Arabidopsis MAPK kinase kinase (AtMEKK1) and induction of AtMEKK1-AtMEK1 pathway by wounding. Hadiarto, T., Nanmori, T., Matsuoka, D., Iwasaki, T., Sato, K., Fukami, Y., Azuma, T., Yasuda, T. Planta (2006) [Pubmed]
  7. Identification of a possible MAP kinase cascade in Arabidopsis thaliana based on pairwise yeast two-hybrid analysis and functional complementation tests of yeast mutants. Mizoguchi, T., Ichimura, K., Irie, K., Morris, P., Giraudat, J., Matsumoto, K., Shinozaki, K. FEBS Lett. (1998) [Pubmed]
  8. Functional complementation of the Schizosaccharomyces pombe wis1 mutant by Arabidopsis MEK1 and non-catalytic enhancement by CTR1. Pan, Z., Chang, C. FEBS Lett. (1999) [Pubmed]
  9. The acceptor availability at photosystem I and ABA control nuclear expression of 2-Cys peroxiredoxin-A in Arabidopsis thaliana. Baier, M., Ströher, E., Dietz, K.J. Plant Cell Physiol. (2004) [Pubmed]
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