Gene Review:
PRB1 - proteinase B
Saccharomyces cerevisiae S288c
Synonyms:
Cerevisin, PrB, Proteinase YSCB, Vacuolar protease B, YEL060C
- Cloning and characterisation of pepC, a gene encoding a serine protease from Aspergillus niger. Frederick, G.D., Rombouts, P., Buxton, F.P. Gene (1993)
- Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction. Takeshige, K., Baba, M., Tsuboi, S., Noda, T., Ohsumi, Y. J. Cell Biol. (1992)
- Processing pathway for protease B of Saccharomyces cerevisiae. Moehle, C.M., Dixon, C.K., Jones, E.W. J. Cell Biol. (1989)
- Biogenesis of the yeast lysosome (vacuole): biosynthesis and maturation of proteinase yscB. Mechler, B., Hirsch, H.H., Müller, H., Wolf, D.H. EMBO J. (1988)
- Maturation of vacuolar (lysosomal) enzymes in yeast: proteinase yscA and proteinase yscB are catalysts of the processing and activation event of carboxypeptidase yscY. Mechler, B., Müller, H., Wolf, D.H. EMBO J. (1987)
- Resolution of organelle docking and fusion kinetics in a cell-free assay. Merz, A.J., Wickner, W.T. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Biogenesis of the yeast vacuole (lysosome). The use of active-site mutants of proteinase yscA to determine the necessity of the enzyme for vacuolar proteinase maturation and proteinase yscB stability. Rupp, S., Wolf, D.H. Eur. J. Biochem. (1995)
- Consequences of growth media, gene copy number, and regulatory mutations on the expression of the PRB1 gene of Saccharomyces cerevisiae. Moehle, C.M., Jones, E.W. Genetics (1990)
- Biogenesis of the yeast vacuole (lysosome). Signal sequence deletion of the vacuolar aspartic proteinase yscA does not block maturation of vacuolar proteinases. Rupp, S., Wolf, D.H. Biol. Chem. Hoppe-Seyler (1993)
- Protease B of Saccharomyces cerevisiae: isolation and regulation of the PRB1 structural gene. Moehle, C.M., Aynardi, M.W., Kolodny, M.R., Park, F.J., Jones, E.W. Genetics (1987)
- Pharmacological and biochemical characterization of the mouse 5HT5A serotonin receptor heterologously produced in the yeast Saccharomyces cerevisiae. Bach, M., Sander, P., Haase, W., Reiländer, H. Recept. Channels (1996)
- The PBN1 gene of Saccharomyces cerevisiae: an essential gene that is required for the post-translational processing of the protease B precursor. Naik, R.R., Jones, E.W. Genetics (1998)
- Regulation of the proteinase B structural gene PRB1 in Saccharomyces cerevisiae. Naik, R.R., Nebes, V., Jones, E.W. J. Bacteriol. (1997)
- Cysteine peptidases CPA and CPB are vital for autophagy and differentiation in Leishmania mexicana. Williams, R.A., Tetley, L., Mottram, J.C., Coombs, G.H. Mol. Microbiol. (2006)
- Biogenesis of the yeast vacuole (lysosome). Mutation in the active site of the vacuolar serine proteinase yscB abolishes proteolytic maturation of its 73-kDa precursor to the 41.5-kDa pro-enzyme and a newly detected 41-kDa peptide. Hirsch, H.H., Schiffer, H.H., Müller, H., Wolf, D.H. Eur. J. Biochem. (1992)
- Vacuolar and extracellular maturation of Saccharomyces cerevisiae proteinase A. Wolff, A.M., Din, N., Petersen, J.G. Yeast (1996)
- Expression and degradation of the cystic fibrosis transmembrane conductance regulator in Saccharomyces cerevisiae. Kiser, G.L., Gentzsch, M., Kloser, A.K., Balzi, E., Wolf, D.H., Goffeau, A., Riordan, J.R. Arch. Biochem. Biophys. (2001)
- Genetic properties of mutations at the PEP4 locus in Saccharomyces cerevisiae. Zubenko, G.S., Park, F.J., Jones, E.W. Genetics (1982)
- The proteinase yscB inhibitor (PB12) gene of yeast and studies on the function of its protein product. Schu, P., Suarez Rendueles, P., Wolf, D.H. Eur. J. Biochem. (1991)