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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Information Theory

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Disease relevance of Information Theory


High impact information on Information Theory


Biological context of Information Theory

  • DNA sequences to which the OxyR protein binds under oxidizing conditions were analyzed by the sequence logo method, a quantitative graphic technique based on information theory [6].

Associations of Information Theory with chemical compounds

  • Information Theory and a geometric approach to Factor Analysis are two techniques that when used in combination, provide important information on the expected two-dimensional performance [7].
  • T(10), a measure of performance consistency from information theory, was lower for chlorhexidine-treated subjects (2.02 +/- 0.11 bits) than controls (2.73 +/- 0.11 bits) (P < 0.0001) [8].
  • The selected topological indices based on connectivity (M, 1chi(v)), on distance matrix (W, (o)B, MTI) and on information theory (I(AC), I(AC)) were calculated for these tocopherols [9].
  • The use of information theory and numerical taxonomy methods for evaluating the quality of thin-layer chromatographic separations of flavonoid constituents of Matricariae flos [10].

Gene context of Information Theory

  • The GOR V algorithm combines information theory, Bayesian statistics and evolutionary information [11].
  • An information theory quality score for reagent sera [12].
  • The optimal combination as determined by Information Theory and Factor Analysis consisted of a C18 column with a methanol mobile phase in the first dimension and a carbon clad zirconia column with an acetonitrile mobile phase in the second dimension [7].
  • We criticize the prerequisites of the traditional approach to ERP analysis and propose to consider ERP instead in terms of dynamical system theory and information theory [13].
  • Consistency of identification for the 10 stimuli (T10) and for each stimulus pair (T2) was quantified with measures derived from information theory [14].


  1. Mutual information analysis and detection of interictal morphological differences in interictal epileptiform discharges of patients with partial epilepsies. Varma, N.K., Kushwaha, R., Beydoun, A., Williams, W.J., Drury, I. Electroencephalography and clinical neurophysiology. (1997) [Pubmed]
  2. Development and refinement of pregnane X receptor (PXR) DNA binding site model using information theory: insights into PXR-mediated gene regulation. Vyhlidal, C.A., Rogan, P.K., Leeder, J.S. J. Biol. Chem. (2004) [Pubmed]
  3. Information analysis of Fis binding sites. Hengen, P.N., Bartram, S.L., Stewart, L.E., Schneider, T.D. Nucleic Acids Res. (1997) [Pubmed]
  4. Application of information theory to decision analysis in potentially prostaglandin-responsive neonates. Danford, D.A., Gutgesell, H.P., McNamara, D.G. J. Am. Coll. Cardiol. (1986) [Pubmed]
  5. On the origin and evolution of the genetic code. Jiménez-Sánchez, A. J. Mol. Evol. (1995) [Pubmed]
  6. Reading of DNA sequence logos: prediction of major groove binding by information theory. Schneider, T.D. Meth. Enzymol. (1996) [Pubmed]
  7. Separation of oligostyrene isomers in a complex mixture using two-dimensional heart-cutting reversed-phased liquid chromatography. Gray, M.J., Dennis, G.R., Slonecker, P.J., Shalliker, R.A. Journal of chromatography. A. (2004) [Pubmed]
  8. Taste confusions following chlorhexidine treatment. Gent, J.F., Frank, M.E., Hettinger, T.P. Chem. Senses (2002) [Pubmed]
  9. Chromatographic separation of tocopherols. Pyka, A., Sliwiok, J. Journal of chromatography. A. (2001) [Pubmed]
  10. The use of information theory and numerical taxonomy methods for evaluating the quality of thin-layer chromatographic separations of flavonoid constituents of Matricariae flos. Medić-Sarić, M., Stanić, G., Bosnjak, I. Die Pharmazie. (2001) [Pubmed]
  11. GOR V server for protein secondary structure prediction. Sen, T.Z., Jernigan, R.L., Garnier, J., Kloczkowski, A. Bioinformatics (2005) [Pubmed]
  12. An information theory quality score for reagent sera. Mickey, M.R., Mittal, K.K. Tissue Antigens (1981) [Pubmed]
  13. Symbolic dynamics of event-related brain potentials. Graben, P., Saddy, J.D., Schlesewsky, M., Kurths, J. Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics. (2000) [Pubmed]
  14. A confusion matrix for the study of taste perception. Hettinger, T.P., Gent, J.F., Marks, L.E., Frank, M.E. Perception & psychophysics. (1999) [Pubmed]
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