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Disease relevance of Mycotoxicosis


High impact information on Mycotoxicosis

  • Identification of swainsonine as a probable contributory mycotoxin in moldy forage mycotoxicoses [2].
  • Histopathology of Mycotoxicosis produced in Swiss albino mice by metabolites of some fungal isolates [3].
  • Strains of F. roseum isolated in various parts of the world form feed implicated in animal mycotoxicosis produced monoacetoxyscirpenol, diacetoxyscirpenol, deoxynivalenol, and zearalenone [4].
  • Fumonisin mycotoxicosis in pigs causes a decrease in mean aortic pressure, an increase in mean pulmonary arterial pressure, and increases in serum concentrations of sphinganine (3.2 microM) and sphingosine (1.4 microM) [5].
  • Because mycophenolic acid is a potent immunosuppressant and synergistic mycotoxicosis studies involving human consumption have not been carried out on this metabolite, spoilage of commercially marketed produce caused by P. brevicompactum is a concern [6].

Chemical compound and disease context of Mycotoxicosis


Biological context of Mycotoxicosis


Anatomical context of Mycotoxicosis


Gene context of Mycotoxicosis

  • However, supplementation with antioxidant nutrients to prevent mycotoxicosis has been controversial [15].
  • The results of this study suggest that NOS may be involved in mycotoxicoses [16].


  1. Fumonisin B1 production by Fusarium species other than F. moniliforme in section Liseola and by some related species. Nelson, P.E., Plattner, R.D., Shackelford, D.D., Desjardins, A.E. Appl. Environ. Microbiol. (1992) [Pubmed]
  2. Identification of swainsonine as a probable contributory mycotoxin in moldy forage mycotoxicoses. Broquist, H.P., Mason, P.S., Hagler, W.M., Harris, T.M. Appl. Environ. Microbiol. (1984) [Pubmed]
  3. Histopathology of Mycotoxicosis produced in Swiss albino mice by metabolites of some fungal isolates. Gupta, J., Pathak, B., Sethi, N., Vora, V.C. Appl. Environ. Microbiol. (1981) [Pubmed]
  4. Natural occurrence of Fusarium toxins in feedstuff. Mirocha, C.J., Pathre, S.V., Schauerhamer, B., Christensen, C.M. Appl. Environ. Microbiol. (1976) [Pubmed]
  5. Effects of exogenous sphinganine, sphingosine, and sphingosine-1-phosphate on relaxation and contraction of porcine thoracic aortic and pulmonary arterial rings. Hsiao, S.H., Constable, P.D., Smith, G.W., Haschek, W.M. Toxicol. Sci. (2005) [Pubmed]
  6. Mycotoxin production and postharvest storage rot of ginger (Zingiber officinale) by Penicillium brevicompactum. Overy, D.P., Frisvad, J.C. J. Food Prot. (2005) [Pubmed]
  7. Citrinin mycotoxicosis in the rabbit: ultrastructural alterations. Hanika, C., Carlton, W.W., Hinsman, E.J., Tuite, J. Vet. Pathol. (1986) [Pubmed]
  8. Lipoic acid as a potential first agent for protection from mycotoxins and treatment of mycotoxicosis. Rogers, S.A. Arch. Environ. Health (2003) [Pubmed]
  9. Mycotoxin detoxication of animal feed by different adsorbents. Huwig, A., Freimund, S., Käppeli, O., Dutler, H. Toxicol. Lett. (2001) [Pubmed]
  10. T-2 toxemia and brain prostaglandins. Shohami, E., Feuerstein, G. Prostaglandins (1986) [Pubmed]
  11. Patulin mycotoxicosis in Swiss ICR mice. McKinley, E.R., Carlton, W.W. Food and cosmetics toxicology. (1980) [Pubmed]
  12. Citrinin mycotoxicosis in the rat. I. Toxicology and pathology. Jordan, W.H., Carlton, W.W., Sansing, G.A. Food and cosmetics toxicology. (1978) [Pubmed]
  13. Effects of immunizing gilts against zearalenone on height of vaginal epithelium and urinary excretion of zearalenone. MacDougald, O.A., Thulin, A.J., Weldon, W.C., Pestka, J.J., Fogwell, R.L. J. Anim. Sci. (1990) [Pubmed]
  14. Morphology and ultrastructure of small intestine mucosa in gilts with zearalenone mycotoxicosis. Obremski, K., Gajecka, M., Zielonka, L., Jakimiuk, E., Gajecki, M. Polish journal of veterinary sciences. (2005) [Pubmed]
  15. Antioxidant nutrients and mycotoxins. Atroshi, F., Rizzo, A., Westermarck, T., Ali-Vehmas, T. Toxicology (2002) [Pubmed]
  16. Effect of Aspergillus terreus mycotoxins on nitric oxide synthase activity in human erythroid K-562 cells. Pugliese, A., Savarino, A., Vidotto, V., Cantamessa, C., Pescarmona, G.P. Cell Biochem. Funct. (1999) [Pubmed]
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