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MeSH Review:

Osteoradionecrosis

Chang, K.P. et al., Mitchell, M.J. et al., Harris, M., Beyzadeoglu, M. et al., Patel, P. et al., et al.

Saunders, Delanian, Depondt, Lefaix, Beyzadeoglu, Dirican, Oysul, Ozen, Ucok,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Osteoradionecrosis

Ruptured internal carotid pseudoaneurysm in a nasopharyngeal carcinoma patient with skull base osteoradionecrosis [1].

High impact information on Osteoradionecrosis

A clinical staging system and treatment guidelines for maxillary osteoradionecrosis in irradiated nasopharyngeal carcinoma patients [2].
Major healing of refractory mandible osteoradionecrosis after treatment combining pentoxifylline and tocopherol: a phase II trial [3].
In osteoradionecrosis of the spine, hematopoietic cellular elements of the spinal marrow are replaced with fat, which has high signal intensity on T1-weighted magnetic resonance images and intermediate signal intensity on T2-weighted images [4].
CONCLUSIONS: For the different radiation beams studied, the irradiation angle between scattering titanium dental implants and the central axis does not significantly affect the total dose that may lead to osteoradionecrosis of the mandible [5].
CSF otorrhea complicating temporal bone osteoradionecrosis in a patient with nasopharyngeal carcinoma [6].

Chemical compound and disease context of Osteoradionecrosis

A case of progressive osteoradionecrosis after cobalt-60 radiation has been presented [7].
The investigation of osteoradionecrosis of the mandible by 99mTc-methylene diphosphonate radionuclide bone scans [8].
Complete healing of severe osteoradionecrosis with treatment combining pentoxifylline, tocopherol and clodronate [9].
Hyperbaric oxygen therapy in the management of carbon monoxide poisoning, osteoradionecrosis, burns, skin grafts, and crush injury [10].
Before 1974, The University of Kentucky Department of Radiation Medicine found osteoradionecrosis (ORN) of the jaw in 10.9% of 220 irradiated cancer patients [11].

Anatomical context of Osteoradionecrosis

METHODS: Between 1994 and 1998 six patients who had irradiation previously for nasopharyngeal carcinoma had skull base osteoradionecrosis [12].
CSF otorrhea complicating osteoradionecrosis of the temporal bone [13].

Gene context of Osteoradionecrosis

The effect of calcitonin on experimental osteoradionecrosis in mice [14].
A false-positive F-18 FDG PET scan caused by osteoradionecrosis and inflammation in patients with nasopharyngeal carcinoma (NPC) has been reported [15].

Analytical, diagnostic and therapeutic context of Osteoradionecrosis

OBJECTIVE: Osteoradionecrosis is one of the most serious complications in radiotherapy of nasopharyngeal carcinoma [12].
False positive fluorine-18 fluorodeoxy-D-glucose positron emission tomography finding caused by osteoradionecrosis in a nasopharyngeal carcinoma patient [16].
A regimen of ultrasound with local debridement and metronidazole has proved to be an effective and practicable treatment for osteoradionecrosis, achieving healing in 10/21 (48%) cases without the need for surgery or sophisticated technology [17].

References

Ruptured internal carotid pseudoaneurysm in a nasopharyngeal carcinoma patient with skull base osteoradionecrosis. Chen, H.C., Lin, C.J., Jen, Y.M., Juan, C.J., Hsueh, C.J., Lee, J.C., Su, W.F. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. (2004) [Pubmed]
A clinical staging system and treatment guidelines for maxillary osteoradionecrosis in irradiated nasopharyngeal carcinoma patients. Cheng, S.J., Lee, J.J., Ting, L.L., Tseng, I.Y., Chang, H.H., Chen, H.M., Kuo, Y.S., Hahn, L.J., Kok, S.H. Int. J. Radiat. Oncol. Biol. Phys. (2006) [Pubmed]
Major healing of refractory mandible osteoradionecrosis after treatment combining pentoxifylline and tocopherol: a phase II trial. Delanian, S., Depondt, J., Lefaix, J.L. Head & neck. (2005) [Pubmed]
Radiation-induced changes in bone. Mitchell, M.J., Logan, P.M. Radiographics : a review publication of the Radiological Society of North America, Inc. (1998) [Pubmed]
Evaluation of scatter dose of dental titanium implants exposed to photon beams of different energies and irradiation angles in head and neck radiotherapy. Beyzadeoglu, M., Dirican, B., Oysul, K., Ozen, J., Ucok, O. Dento maxillo facial radiology. (2006) [Pubmed]
CSF otorrhea complicating temporal bone osteoradionecrosis in a patient with nasopharyngeal carcinoma. Lim, B.Y., Pang, K.P., Low, W.K., Tan, H.M. Ear, nose, & throat journal. (2005) [Pubmed]
Treatment of osteoradionecrosis by transoral hemimandibulectomy: report of case. Friedlander, A.H., Mazzarella, L., Kisner, A. Journal of oral surgery (American Dental Association : 1965) (1979) [Pubmed]
The investigation of osteoradionecrosis of the mandible by 99mTc-methylene diphosphonate radionuclide bone scans. Hutchison, I.L., Cullum, I.D., Langford, J.A., Jarritt, P.H., Ell, P.J., Harris, M. The British journal of oral & maxillofacial surgery. (1990) [Pubmed]
Complete healing of severe osteoradionecrosis with treatment combining pentoxifylline, tocopherol and clodronate. Delanian, S., Lefaix, J.L. The British journal of radiology. (2002) [Pubmed]
Hyperbaric oxygen therapy in the management of carbon monoxide poisoning, osteoradionecrosis, burns, skin grafts, and crush injury. Saunders, P.J. International journal of technology assessment in health care. (2003) [Pubmed]
Osteoradionecrosis of the jaw bones at the University of Kentucky Medical Center. Patel, P., Raybould, T., Maruyama, Y. The Journal of the Kentucky Medical Association. (1989) [Pubmed]
Endoscopic management of skull base osteoradionecrosis. Chang, K.P., Tsang, N.M., Chen, C.Y., Su, J.L., Hao, S.P. Laryngoscope (2000) [Pubmed]
CSF otorrhea complicating osteoradionecrosis of the temporal bone. Sikand, A., Longridge, N. The Journal of otolaryngology. (1991) [Pubmed]
The effect of calcitonin on experimental osteoradionecrosis in mice. Archibald, D., Shklar, G. Journal of oral medicine. (1985) [Pubmed]
Extraordinarily high F-18 FDG uptake caused by radiation necrosis in a patient with nasopharyngeal carcinoma. Hung, G.U., Tsai, S.C., Lin, W.Y. Clinical nuclear medicine. (2005) [Pubmed]
False positive fluorine-18 fluorodeoxy-D-glucose positron emission tomography finding caused by osteoradionecrosis in a nasopharyngeal carcinoma patient. Liu, S.H., Chang, J.T., Ng, S.H., Chan, S.C., Yen, T.C. The British journal of radiology. (2004) [Pubmed]
The conservative management of osteoradionecrosis of the mandible with ultrasound therapy. Harris, M. The British journal of oral & maxillofacial surgery. (1992) [Pubmed]

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