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Chemical Compound Review

diphosphonate     oxido-(oxido-oxo- phosphaniumyl)oxy-oxo...

Synonyms: CHEBI:29262, IN2857, AKOS015903585, P1746, I14-18086, ...
 
 
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Disease relevance of diphosphonate

 

High impact information on diphosphonate

 

Chemical compound and disease context of diphosphonate

 

Biological context of diphosphonate

 

Anatomical context of diphosphonate

 

Associations of diphosphonate with other chemical compounds

 

Gene context of diphosphonate

 

Analytical, diagnostic and therapeutic context of diphosphonate

References

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  2. Use of dichloromethylene diphosphonate in metastatic bone disease. Jung, A., Chantraine, A., Donath, A., van Ouwenaller, C., Turnill, D., Mermillod, B., Kitler, M.E. N. Engl. J. Med. (1983) [Pubmed]
  3. Effects of dichloromethylene diphosphonate on skeletal mobilization of calcium in multiple myeloma. Siris, E.S., Sherman, W.H., Baquiran, D.C., Schlatterer, J.P., Osserman, E.F., Canfield, R.E. N. Engl. J. Med. (1980) [Pubmed]
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  6. Inhibition of calcification of bioprosthetic heart valves by local controlled-release diphosphonate. Levy, R.J., Wolfrum, J., Schoen, F.J., Hawley, M.A., Lund, S.A., Langer, R. Science (1985) [Pubmed]
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  9. Effect of dichloromethylene diphosphonate in Paget's disease of bone and in hypercalcaemia due to primary hyperparathyroidism or malignant disease. Douglas, D.L., Duckworth, T., Russell, R.G., Kanis, J.A., Preston, C.J., Preston, F.E., Prenton, M.A., Woodhead, J.S. Lancet (1980) [Pubmed]
  10. Renal excretion of technetium-99m diphosphonate in osteomalacia. Fogelman, I., Bessent, R.G. Ann. Intern. Med. (1979) [Pubmed]
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  14. Depletion of alveolar macrophages exerts protective effects in pulmonary tuberculosis in mice. Leemans, J.C., Juffermans, N.P., Florquin, S., van Rooijen, N., Vervoordeldonk, M.J., Verbon, A., van Deventer, S.J., van der Poll, T. J. Immunol. (2001) [Pubmed]
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  16. Heterotopic bone formation (myositis ossificans) and lower-extremity swelling mimicking deep-venous disease. Orzel, J.A., Rudd, T.G., Nelp, W.B. J. Nucl. Med. (1984) [Pubmed]
  17. Imaging of malignant bone involvement by morphologic, scintigraphic, and hybrid modalities. Even-Sapir, E. J. Nucl. Med. (2005) [Pubmed]
  18. Endocrine and pharmacological suppressors of bone turnover protect against osteopenia in ovariectomized rats. Wronski, T.J., Dann, L.M., Scott, K.S., Crooke, L.R. Endocrinology (1989) [Pubmed]
  19. Immediate renal imaging and renography with 99mTc methylene diphosphonate to assess renal blood flow, excretory function, and anatomy. Glass, E.C., DeNardo, G.L., Hines, H.H. Radiology. (1980) [Pubmed]
  20. Effects of dichloromethylene diphosphonate on serum and urinary calcium in primary hyperparathyroidism. Shane, E., Baquiran, D.C., Bilezikian, J.P. Ann. Intern. Med. (1981) [Pubmed]
  21. An experimental rat model of local bone cancer invasion and its responsiveness to ethane-1-hydroxy-1,1-bis(phosphonate). Guaitani, A., Sabatini, M., Coccioli, G., Cristina, S., Garattini, S., Bartosek, I. Cancer Res. (1985) [Pubmed]
  22. Tumor necrosis factor-induced, superoxide-mediated neutrophil accumulation in cold ischemic/reperfused rat liver. Shibuya, H., Ohkohchi, N., Tsukamoto, S., Satomi, S. Hepatology (1997) [Pubmed]
  23. Phagocytic lining cells determine local expression of inflammation in type II collagen-induced arthritis. van Lent, P.L., Holthuysen, A.E., van den Bersselaar, L.A., van Rooijen, N., Joosten, L.A., van de Loo, F.A., van de Putte, L.B., van den Berg, W.B. Arthritis Rheum. (1996) [Pubmed]
  24. Prospective evaluation of sacroiliac scintigraphy in chronic inflammatory back pain. Esdaile, J.M., Rosenthall, L., Terkeltaub, R., Kloiber, R. Arthritis Rheum. (1980) [Pubmed]
  25. Technetium-99m diphosphonate retention in hyperparathyroidism. Heath, H. Ann. Intern. Med. (1980) [Pubmed]
  26. Kupffer cell depletion partially prevents hepatic heme oxygenase 1 messenger RNA accumulation in systemic inflammation in mice: role of interleukin 1beta. Rizzardini, M., Zappone, M., Villa, P., Gnocchi, P., Sironi, M., Diomede, L., Meazza, C., Monshouwer, M., Cantoni, L. Hepatology (1998) [Pubmed]
  27. Effects of diphosphonates on glycosaminoglycan synthesis and proteoglycan aggregation in normal adult articular cartilage. Palmoski, M., Brandt, K. Arthritis Rheum. (1978) [Pubmed]
  28. Secondary hyperparathyroidism associated with dichloromethane diphosphonate treatment of Paget's disease. Harris, S.T., Neer, R.M., Segre, G.V., Petkau, A.J., Tully, G.L., Daly, M., Potts, J.T. J. Clin. Endocrinol. Metab. (1982) [Pubmed]
  29. Regulation of immune response to inhaled antigen by alveolar macrophages: differential effects of in vivo alveolar macrophage elimination on the induction of tolerance vs. immunity. Thepen, T., McMenamin, C., Oliver, J., Kraal, G., Holt, P.G. Eur. J. Immunol. (1991) [Pubmed]
  30. Fever after zoledronic acid administration is due to increase in TNF-alpha and IL-6. Dicuonzo, G., Vincenzi, B., Santini, D., Avvisati, G., Rocci, L., Battistoni, F., Gavasci, M., Borzomati, D., Coppola, R., Tonini, G. J. Interferon Cytokine Res. (2003) [Pubmed]
  31. Intestinal drug delivery systems with biodegradable microspheres targeting mucosal immune-regulating cells for chronic inflammatory colitis. Okazaki, K., Nakase, H., Watanabe, N., Tabata, Y., Ikada, Y., Chiba, T. J. Gastroenterol. (2002) [Pubmed]
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  33. Whole body retention of diphosphonate in rheumatoid arthritis. Steven, M.M., Sturrock, R.D., Fogelman, I., Smith, M.L. J. Rheumatol. (1982) [Pubmed]
  34. Diphosphonates and phosphate homoeostasis in man. McCloskey, E.V., Yates, A.J., Gray, R.E., Hamdy, N.A., Galloway, J., Kanis, J.A. Clin. Sci. (1988) [Pubmed]
  35. Symptomatic hypocalcaemia after treatment with high-dose aminohydroxypropylidene diphosphonate. Jodrell, D.I., Iveson, T.J., Smith, I.E. Lancet (1987) [Pubmed]
  36. Circulation of human hematopoietic cells in severe combined immunodeficient mice after Cl2MDP-liposome-mediated macrophage depletion. Fraser, C.C., Chen, B.P., Webb, S., van Rooijen, N., Kraal, G. Blood (1995) [Pubmed]
  37. Effects of dichloromethylene diphosphonate in women with breast carcinoma metastatic to the skeleton. Siris, E.S., Hyman, G.A., Canfield, R.E. Am. J. Med. (1983) [Pubmed]
  38. Macrophage depletion increases the safety, efficacy and persistence of adenovirus-mediated gene transfer in vivo. Kuzmin, A.I., Finegold, M.J., Eisensmith, R.C. Gene Ther. (1997) [Pubmed]
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