Disease relevance of Oocyte Donation

• Serum CA 125 was measured by radioimmunoassay during the first trimester at intervals of 2 weeks in a woman with Turner's syndrome, who conceived following ovum donation from a healthy anonymous donor [1].
• Pituitary apoplexy after leuprolide injection for ovum donation [2].
• A pregnancy obtained in a patient with 46XY gonadal dysgenesis (Swyer's syndrome) after ovum donation and IVF/ET is described [3].

High impact information on Oocyte Donation

• The present study demonstrates that coculture of human embryos with AEEC and blastocyst transfer is safe, ethical, and effective and constitutes a new approach to improve implantation in patients with IF undergoing ovum donation, but not in IVF patients [4].
• Persistent and consistent monitoring have practical implications for genetic and fertility counselling in the era when women with premature ovarian failure usually seek ovum donation [5].
• OBJECTIVE: To report the novel use of hMG and the GnRH antagonist for endometrial preparation and synchronization in a woman participating in an ovum donation program who was resistant to endometrial preparation with estrogen replacement [6].
• Serum CA 125 in a pregnancy generated by ovum donation [1].
• Serum placental protein 14 concentrations in the first trimester of ovum donation pregnancies [7].

Chemical compound and disease context of Oocyte Donation

• To our knowledge, pituitary apoplexy after gonadotropin releasing hormone agonist use for ovum donation has not been previously described [2].

Associations of Oocyte Donation with chemical compounds

• Transdermal estrogen replacement in ovarian failure for ovum donation [8].
• To date, ovum donation (OD) has involved luteinizing hormone (LH) synchronization between recipient and donor for normally cycling women, and a complex steroid replacement regimen given on a sequential and incremental basis for women with primary or secondary ovarian failure [9].

Gene context of Oocyte Donation

• In order to investigate this suggestion further, circulating levels of IGFBP-1 were measured in samples taken throughout pregnancies conceived either spontaneously or following ovum donation [10].
• BACKGROUND: Conception without ovum donation is very rare in patients with Turner syndrome, occurring mainly in mosaics, and only a third of these natural pregnancies are associated with normal outcome [11].

Analytical, diagnostic and therapeutic context of Oocyte Donation

• Fifty-five patients were treated by ovum donation, and a control group of 165 patients underwent IVF [12].
• Preimplantation evaluation and ovum donation are described as measures to minimize the risk for GTD recurrence in a future IVF/embryo transfer [13].
• However, the few studies based on data from assisted reproductive techniques (especially IVF with ovum donation) do not confirm this finding [14].

References