Disease relevance of Stigmatella

• New lessons for combinatorial biosynthesis from myxobacteria. The myxothiazol biosynthetic gene cluster of Stigmatella aurantiaca DW4/3-1 [1].

High impact information on Stigmatella

• During our studies on myxothiazol biosynthesis in the myxobacterium, Stigmatella aurantiaca, we detected a novel biosynthetic route to isovaleric acid [2].
• The pyruvate kinase of Stigmatella aurantiaca is an indole binding protein and essential for development [3].
• Steroid biosynthesis in prokaryotes: identification of myxobacterial steroids and cloning of the first bacterial 2,3(S)-oxidosqualene cyclase from the myxobacterium Stigmatella aurantiaca [4].
• The tufB gene, encoding elongation factor Tu (EF-Tu), from the myxobacterium Stigmatella aurantiaca was cloned and sequenced [5].
• Stigmatellin A (1) isolated from the myxobacterium Stigmatella aurantiaca is a powerful inhibitor of electron transport in mitochondria and chloroplasts [6].

Chemical compound and disease context of Stigmatella

• The PK activity of Stigmatella crude extracts was stimulated by indole [3].
• fbfB, a gene encoding a putative galactose oxidase, is involved in Stigmatella aurantiaca fruiting body formation [7].
• Morphogenetic effects of light and guanine derivatives on the fruiting myxobacterium Stigmatella aurantiaca [8].
• Scanning electron microscopy was used to follow fruiting body formation by pure cultures of Chondromyces crocatus M38 and Stigmatella aurantica [9].
• Here, we report that in Stigmatella aurantiaca, under conditions which promote clumping, inositol phospholipid synthesis and degradation were stimulated with the resulting formation of inositol phosphate and inositol bisphosphate [10].

Biological context of Stigmatella

• The aurachins, new quinoline alkaloids, were extracted with acetone from the biomass of the myxobacterium, Stigmatella aurantiaca strain Sg a15 and purified by column chromatography [11].

Gene context of Stigmatella

• Translation initiation factor IF2 of the myxobacterium Stigmatella aurantiaca: presence of a single species with an unusual N-terminal sequence [12].
• Purification of the DNA-dependent RNA polymerase from the myxobacterium Stigmatella aurantiaca [13].
• Calcium ion induces in the myxobacterium Stigmatella aurantiaca the ability to glide on solid surfaces and to become cohesive (D. F. Gilmore and D. White, J. Bacteriol. 161:113-117, 1985; B. J. Womack, D. F. Gilmore, and D. White, J. Bacteriol. 171:6093-6096, 1989) [14].
• Selective amplification of DNA fragments coding for the G domain of factors IF2 and EF-Tu, two G proteins from the myxobacterium Stigmatella aurantiaca [15].
• The myxobacteria Stigmatella aurantiaca contains a glucokinase activity with a different specificity pattern [16].

References