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Disease relevance of Carthamus


High impact information on Carthamus

  • Nucleotide sequence of a cDNA from Carthamus tinctorius encoding a glycerol-3-phosphate acyl transferase [3].
  • 1. [14C]Oleoyl-CoA was metabolized rapidly and essentially completely by microsomal preparations from developing safflower (Carthamus tinctorius) cotyledons, and most of the [14C]oleate was incorporated into 3-sn-phosphatidylcholine [4].
  • A novel flavanone glycoside, (2S)-4',5,6,7-tetrahydroxyflavavone 6-O-beta-D-glucopyranoside was isolated from the ethyl acetate extract of the flowers of Carthamus tinctorium by high-speed counter-current chromatography (HSCCC) [5].
  • Previous work has shown that hydroxysafflor yellow A (HSYA), extracted from Carthamus tinctorius L. markedly extended the coagulation time in mice and exhibited a significant antithrombotic effect in rats [6].
  • Carthamin, a red quinochalcone pigment in safflower (Carthamus tinctorius L.), is enzymatically converted from a yellow precursor, precarthamin [7].

Biological context of Carthamus


Associations of Carthamus with chemical compounds


Gene context of Carthamus


  1. The role of cytochrome b5 in delta 12 desaturation of oleic acid by microsomes of safflower (Carthamus tinctorius L.). Kearns, E.V., Hugly, S., Somerville, C.R. Arch. Biochem. Biophys. (1991) [Pubmed]
  2. Prevention of experimental autoimmune encephalomyelitis in Lewis rats by a novel fungal source of gamma-linolenic acid. Harbige, L.S., Yeatman, N., Amor, S., Crawford, M.A. Br. J. Nutr. (1995) [Pubmed]
  3. Nucleotide sequence of a cDNA from Carthamus tinctorius encoding a glycerol-3-phosphate acyl transferase. Bhella, R.S., MacKenzie, S.L. Plant Physiol. (1994) [Pubmed]
  4. Evidence for an oleoyl phosphatidylcholine desaturase in microsomal preparations from cotyledons of safflower (Carthamus tinctorius) seed. Slack, C.R., Roughan, P.G., Browse, J. Biochem. J. (1979) [Pubmed]
  5. Isolation of a novel flavanone 6-glucoside from the flowers of Carthamus tinctorium (Honghua) by high-speed counter-current chromatography. Zhao, M., Ito, Y., Tu, P. Journal of chromatography. A. (2005) [Pubmed]
  6. Neuroprotective effects of hydroxysafflor yellow A: in vivo and in vitro studies. Zhu, H., Wang, Z., Ma, C., Tian, J., Fu, F., Li, C., Guo, D., Roeder, E., Liu, K. Planta Med. (2003) [Pubmed]
  7. Purification and characterization of precarthamin decarboxylase from the yellow petals of Carthamus tinctorius L. Cho, M.H., Hahn, T.R. Arch. Biochem. Biophys. (2000) [Pubmed]
  8. The acylation of sn-glycerol 3-phosphate and the metabolism of phosphatidate in microsomal preparations from the developing cotyledons of safflower (Carthamus tinctorius L.) seed. Griffiths, G., Stobart, A.K., Stymne, S. Biochem. J. (1985) [Pubmed]
  9. Growth temperature control of the linoleic acid content in safflower (Carthamus tinctorius) seed oil. Esteban, A.B., Sicardo, M.D., Mancha, M., Martínez-Rivas, J.M. J. Agric. Food Chem. (2004) [Pubmed]
  10. Antioxidative compounds isolated from safflower (Carthamus tinctorius L.) oil cake. Zhang, H.L., Nagatsu, A., Watanabe, T., Sakakibara, J., Okuyama, H. Chem. Pharm. Bull. (1997) [Pubmed]
  11. Lack of significant inhibitory effects of a plant lignan tracheloside on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mammary carcinogenesis in female Sprague-Dawley rats. Kitamura, Y., Yamagishi, M., Okazaki, K., Son, H.Y., Imazawa, T., Nishikawa, A., Iwata, T., Yamauchi, Y., Kasai, M., Tsutsumi, K., Hirose, M. Cancer Lett. (2003) [Pubmed]
  12. Interaction of 5,7-dihydroxy-4'-methoxyflavone with a multisubunit protein, carmin: thermodynamics and kinetics of interaction. Rao, K.S., Suryaprakash, P., Prakash, V. Int. J. Pept. Protein Res. (1996) [Pubmed]
  13. Concentrations of long-chain acyl-acyl carrier proteins during fatty acid synthesis by chloroplasts isolated from pea (Pisum sativum), safflower (Carthamus tinctoris), and amaranthus (Amaranthus lividus) leaves. Roughan, G., Nishida, I. Arch. Biochem. Biophys. (1990) [Pubmed]
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