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Chemical Compound Review

Ascabiol     benzyl benzoate

Synonyms: Benylate, Colebenz, Scabagen, Scabanca, Scabitox, ...
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Disease relevance of Benzylbenzenecarboxylate


Psychiatry related information on Benzylbenzenecarboxylate


High impact information on Benzylbenzenecarboxylate


Chemical compound and disease context of Benzylbenzenecarboxylate


Biological context of Benzylbenzenecarboxylate


Anatomical context of Benzylbenzenecarboxylate

  • After location of the radioactive microspheres within the intact oviducts, the genital tracts were removed and cleared in benzyl benzoate [17].
  • Effect of castor oil and benzyl benzoate used as a vehicle for antiandrogens on the adrenal cortex [18].
  • The alkaline solution method for detecting uterine implantation sites (metrial glands or spots after delivery), which indicate the position of the embryo, was compared with conventional methods using Turnbull blue (Salewski's technique) and benzyl benzoate (Orsini's technique) in rats [19].
  • Benzyl benzoate cleared fixed or unfixed uteri and allowed observation of the metrial glands and spots after delivery although the entire process required a few days and the specimens became hard and shriveled [19].

Associations of Benzylbenzenecarboxylate with other chemical compounds


Gene context of Benzylbenzenecarboxylate


Analytical, diagnostic and therapeutic context of Benzylbenzenecarboxylate

  • Clinical effects of benzyl benzoate in the prevention of house-dust-mite allergy. Results of a prospective, double-blind, multicenter study [4].
  • Rheological experiments showed that the flow properties of PLGA/benzyl benzoate solutions were affected by a combination of degradation and gelation; the latter was also detected by an endotherm in DSC and by three-dimensional structure formation studies by rheology [8].
  • The control group had the usual house dust mite control measures including the use of vinyl covers for mattresses and pillows while the treatment group had application of benzyl benzoate to mattresses and carpets in the bedroom and the most commonly used room, in addition to the above control measures [25].
  • A significant higher mortality of eggs was evident after treatment with (i) disulfiram, (ii) benzyl benzoate, (iii) these two substances mixed, and (iv) Tenutex [20].
  • Based on LD(50) values in fabric piece contact toxicity bioassays, the acaricidal activities of benzoic acid (4.80 microg cm(-2)) and paeonol (5.29 microg cm(-2)) were comparable to that of benzyl benzoate (4.46 microg cm(-2)) but more pronounced than those of DEET (30.03 microg cm(-2)) and dibutyl phthalate (25.23 microg cm(-2)) [26].


  1. Benzyl benzoate moist powder: investigation of acaricidal [correction of acarical] activity in cultures and reduction of dust mite allergens in carpets. Hayden, M.L., Rose, G., Diduch, K.B., Domson, P., Chapman, M.D., Heymann, P.W., Platts-Mills, T.A. J. Allergy Clin. Immunol. (1992) [Pubmed]
  2. Prevention of mite infestation of bedding by means of an impregnated sheet. A randomized controlled trial. Burr, M.L., Dean, B.V., Butland, B.K., Neale, E. Allergy (1988) [Pubmed]
  3. Ivermectin alone or in combination with benzyl benzoate in the treatment of human immunodeficiency virus-associated scabies. Alberici, F., Pagani, L., Ratti, G., Viale, P. Br. J. Dermatol. (2000) [Pubmed]
  4. Clinical effects of benzyl benzoate in the prevention of house-dust-mite allergy. Results of a prospective, double-blind, multicenter study. Kroidl, R.F., Göbel, D., Balzer, D., Trendelenburg, F., Schwichtenberg, U. Allergy (1998) [Pubmed]
  5. Acaricidal activity of Cnidium officinale rhizome-derived butylidenephthalide against Tyrophagus putrescentiae (Acari: Acaridae). Kwon, J.H., Ahn, Y.J. Pest Manag. Sci. (2003) [Pubmed]
  6. Mite control with low temperature washing-II. Elimination of living mites on clothing. Bischoff, E.R., Fischer, A., Liebenberg, B., Kniest, F.M. Clin. Exp. Allergy (1998) [Pubmed]
  7. Acaricidal activity of Melaleuca alternifolia (tea tree) oil: in vitro sensitivity of sarcoptes scabiei var hominis to terpinen-4-ol. Walton, S.F., McKinnon, M., Pizzutto, S., Dougall, A., Williams, E., Currie, B.J. Archives of dermatology. (2004) [Pubmed]
  8. Structure formation in injectable poly(lactide-co-glycolide) depots. Wang, L., Kleiner, L., Venkatraman, S. Journal of controlled release : official journal of the Controlled Release Society. (2003) [Pubmed]
  9. Squamocin and benzyl benzoate, acaricidal components of Uvaria pauci-ovulata bark extracts. Raynaud, S., Fourneau, C., Laurens, A., Hocquemiller, R., Loiseau, P., Bories, C. Planta Med. (2000) [Pubmed]
  10. Confocal laser scanning microscopy of apoptosis in organogenesis-stage mouse embryos. Zucker, R.M., Hunter, S., Rogers, J.M. Cytometry. (1998) [Pubmed]
  11. Acaricidal activity of Paeonia suffruticosa root bark-derived compounds against Dermatophagoides farinae and Dermatophagoides pteronyssinus (Acari: Pyroglyphidae). Kim, H.K., Tak, J.H., Ahn, Y.J. J. Agric. Food Chem. (2004) [Pubmed]
  12. Treatment of scabies with disulfiram and benzyl benzoate emulsion: a controlled study. Landegren, J., Borglund, E., Storgårds, K. Acta Derm. Venereol. (1979) [Pubmed]
  13. Efficacy and tolerability of a new synergized pyrethrins thermofobic foam in comparison with benzyl benzoate in the treatment of scabies in convicts: the ISAC study (Studio Della scabbia in ambiente carcerario). Biele, M., Campori, G., Colombo, R., De Giorgio, G., Frascione, P., Sali, R., Starnini, G., Milani, M. Journal of the European Academy of Dermatology and Venereology : JEADV. (2006) [Pubmed]
  14. Cost-benefit analysis of ivermectin, permethrin and benzyl benzoate in the management of infantile and childhood scabies. Elgart, M.L. Expert opinion on pharmacotherapy. (2003) [Pubmed]
  15. Mite control with low temperature washing. I. Elimination of living mites on carpet pieces. Bischoff, E.R., Fischer, A., Liebenberg, B., Kniest, F.M. Clin. Exp. Allergy (1996) [Pubmed]
  16. Food protective and color alteration effects of acaricidal aldehydes on Tyrophagus putrescentiae (Schrank). Sung, B.K., Lim, J.H., Lee, H.S. J. Food Prot. (2006) [Pubmed]
  17. Use of radioactive microspheres for studies of tubal ovum transport. Pauerstein, C.J., Hodgson, B.J., Young, R.J., Chatkoff, M.L., Eddy, C.A. Am. J. Obstet. Gynecol. (1975) [Pubmed]
  18. Effect of castor oil and benzyl benzoate used as a vehicle for antiandrogens on the adrenal cortex. Migally, N. Arch. Androl. (1979) [Pubmed]
  19. The usefulness of alkaline solutions for clearing the uterus and staining implantation sites in rats. Yamada, T., Ohsawa, K., Ohno, H. Jikken Dobutsu (1988) [Pubmed]
  20. Control of the human head louse with disulfiram and benzyl benzoate emulsions. A laboratory study. Brinck-Lindroth, G., Lundqvist, L., Nilsson, A. Acta Derm. Venereol. (1984) [Pubmed]
  21. Placebo-controlled study of the mite allergen-reducing effect of tannic acid plus benzyl benzoate on carpets in homes of children with house dust mite sensitization and asthma. Lau, S., Wahn, J., Schulz, G., Sommerfeld, C., Wahn, U. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology. (2002) [Pubmed]
  22. Klaivanolide, an antiprotozoal lactone from Uvaria klaineana. Akendengue, B., Roblot, F., Loiseau, P.M., Bories, C., Ngou-Milama, E., Laurens, A., Hocquemiller, R. Phytochemistry (2002) [Pubmed]
  23. Crusted scabies associated with systemic lupus erythematosus: response to benzyl benzoate therapy. Chutimunt, N. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. (1996) [Pubmed]
  24. Effect of co-solvents on the controlled release of calcitonin polypeptide from in situ biodegradable polymer implants. Prabhu, S., Tran, L.P., Betageri, G.V. Drug delivery. (2005) [Pubmed]
  25. Effect of application of benzyl benzoate on house dust mite allergen levels. Chang, J.H., Becker, A., Ferguson, A., Manfreda, J., Simons, E., Chan, H., Noertjojo, K., Chan-Yeung, M. Ann. Allergy Asthma Immunol. (1996) [Pubmed]
  26. Acaricidal activities of paeonol and benzoic acid from Paeonia suffruticosa root bark and monoterpenoids against Tyrophagus putrescentiae (Acari: Acaridae). Tak, J.H., Kim, H.K., Lee, S.H., Ahn, Y.J. Pest Manag. Sci. (2006) [Pubmed]
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