Disease relevance of Aizoaceae

• The underlying molecular mechanisms of the antihepatotoxic activity of Trianthema portulacastrum by monitoring its effect on mouse liver DNA-chain break, sugar-base damage and chromosomal aberrations, during chronic or acute treatment with carbon tetrachloride (CCl(4)) have been studied [1].
• Two sensitive methods, RT-PCR with phenol-extracted RNA or Triton X-100-released RNA and immunocapture RT-PCR (IR-RT-PCR) were used for the detection of Beet yellows virus (BYV) in young and old leaves of Tetragonia expansa and sugar beet (Beta vulgaris) and in sugar beet roots [2].

High impact information on Aizoaceae

• In this study we investigated factors involved in the diversification of Argyroderma, a genus within the most spectacular of the Cape radiations, that of the Ruschioid subfamily of the Aizoaceae [3].
• Vector-expressed cp of Beet necrotic yellow vein virus (BNYVV) assembled in Chenopodium quinoa, Tetragonia expansa and Beta vulgaris leaves into particles resembling true BNYVV particles [4].
• On immunoblots of protein from BYV-infected Tetragonia expansa plants, four MAbs against the MT recognized a approximately 63 kDa protein, and two MAbs against the HEL recognized a approximately 100 kDa protein [5].
• Cadmium effects on growth and mineral nutrition of two halophytes: Sesuvium portulacastrum and Mesembryanthemum crystallinum [6].
• Trianthenol: an antifungal tetraterpenoid from Trianthema portulacastrum (Aizoaceae) [7].

Biological context of Aizoaceae

• Inhibition of early DNA-damage and chromosomal aberrations by Trianthema portulacastruml. In carbon tetrachloride-induced mouse liver damage [1].

Associations of Aizoaceae with chemical compounds

• Protective role of Trianthema portulacastrum against diethylnitrosoamine-induced experimental hepatocarcinogenesis [8].
• An antifungal tetraterpenoid named trianthenol 1 has been isolated from the chloroform extract of Trianthema portulacastrum [7].
• A benzaldehyde derivative 2, a pentacyclic triterpenoid 3 and benzoic acid derivatives 4-5 are also reported for the first time from Trianthema portulacastrum [7].
• Antihepatotoxic potential of Trianthema portulacastrum in carbon tetrachloride-induced chronic hepatocellular injury in mice: reflection in haematological, histological and biochemical characteristics [9].
• Ethanol control, chloroform controls and Trianthema controls displayed similar values as that of normal untreated animals with regard to the different parameters tested [10].

Gene context of Aizoaceae

• The effect of an ethanolic extract of the plant Trianthema portulacastrum L. on the CCl4-induced chronic hepatocellular damage of Swiss albino mice has been investigated [9].
• Trianthema pentandra (whole plant) did not show any decrease in the acid or pepsin content or any increase in mucin; however, it showed a highly significant decrease in the ulcer index [11].
• The chloroform fraction of Trianthema portulacastrum L. has been found to be very effective in restoring glutathione levels and the levels of Phase I (cytochrome P-450 monooxygenase) and Phase II (UDPGT) enzymes, which undergo substantial changes during chemical rat hepatocarcinogenesis [10].

Analytical, diagnostic and therapeutic context of Aizoaceae

• Brine shrimp bioassay of ethanol extracts of Sesuvium verrucosum, Salsola baryosma and Zygophyllum quatarense medicinal plants from Bahrain [12].

References