The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Coleus

 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on Coleus

  • Forskolin is a diterpene derivative of the plant Coleus forskohlii that stimulates adenylate cyclase activity without interacting with cell surface receptors [1].
  • Forskolin (7 beta-acetoxy-8,13-epoxy-1 alpha, 6 beta, 9 alpha-trihydroxylabd-14-en-11-one), a diterpene from the Indian plant Coleus forskohlii, activates cyclic AMP generating systems in a number of mammalian tissues in a rapid and reversible fashion [2].
  • The HPPR protein was purified from suspension cells of Coleus blumei accumulating high levels of rosmarinic acid by ammonium sulfate precipitation, anion exchange chromatography, hydroxylapatite chromatography, chromatography on 2',5'-ADP-Sepharose 4B and SDS-polyacrylamide gel electrophoresis [3].
  • Preliminary studies of ascorbate metabolism in green and albino regions of variegated leaves of Coleus blumei, Benth [4].
  • Green and white variegated leaves of Coleus blumei, Benth. were separated into albino and green sections and used to determine the distribution of vitamin C and L-galactose dehydrogenase activity, an enzyme supposed to be involved in ascorbate metabolism, in heterotrophic and autotrophic foliar fractions [4].
 

Biological context of Coleus

 

Anatomical context of Coleus

 

Associations of Coleus with chemical compounds

  • Stigmasterol from Coleus forskohlii and ecdysterone from Diploclisia glaucescens were inactive constituents isolated during the process of purifying the active principles of the plants [7].
  • Abietane diterpenoids from Coleus xanthanthus [8].
  • Coleus forskohlii hairy root cultures were shown to biotransform methanol and ethanol to the corresponding beta-D-glucopyranosides and beta-D-ribo-hex-3-ulopyranosides, and 2-propanol to its beta-D-glucopyranoside [9].
  • Eight new abietane diterpenoids, coleon U 11-acetate (1), 16-acetoxycoleon U 11-acetate (2), and xanthanthusins F-K (3-8), together with five known analogues, coleon U (9), 16-O-acetylcoleon C (10), coleon U-quinone (11), 8alpha,9alpha-epoxycoleon U-quinone (12), and xanthanthusin E (13), were isolated from the aerial parts of Coleus xanthanthus [8].
  • Cytochemical localization of phenol-oxidizing enzymes in lignifying Coleus blumei stems [10].
 

Analytical, diagnostic and therapeutic context of Coleus

References

  1. Forskolin lowers intraocular pressure by reducing aqueous inflow. Caprioli, J., Sears, M., Bausher, L., Gregory, D., Mead, A. Invest. Ophthalmol. Vis. Sci. (1984) [Pubmed]
  2. Structure-activity relationships for activation of adenylate cyclase by the diterpene forskolin and its derivatives. Seamon, K.B., Daly, J.W., Metzger, H., de Souza, N.J., Reden, J. J. Med. Chem. (1983) [Pubmed]
  3. Purification, cloning and functional expression of hydroxyphenylpyruvate reductase involved in rosmarinic acid biosynthesis in cell cultures of Coleus blumei. Kim, K.H., Janiak, V., Petersen, M. Plant Mol. Biol. (2004) [Pubmed]
  4. Preliminary studies of ascorbate metabolism in green and albino regions of variegated leaves of Coleus blumei, Benth. Peltzer, D., Schwanz, P., Polle, A. Free Radic. Res. (1999) [Pubmed]
  5. The effect of chronic in vivo infusion of forskolin on noradrenergic receptor sensitivity. Suzdak, P.D., Browne, R.G. Psychopharmacology (Berl.) (1985) [Pubmed]
  6. Efficiency of Coleus aromaticus extract in modifying cyclophosphamide and mitomycin-C induced clastogenicity in mouse bone marrow cells. Prasad, S., Naik, P., Vijayalaxmi, K.K. Indian J. Exp. Biol. (2002) [Pubmed]
  7. Chonemorphine, stigmasterol, and ecdysterone: steroids isolated through bioassay-directed plant screening programs. Shah, V.C., D'Sa, A.S., de Souza, N.J. Steroids (1989) [Pubmed]
  8. Abietane diterpenoids from Coleus xanthanthus. Mei, S.X., Jiang, B., Niu, X.M., Li, M.L., Yang, H., Na, Z., Lin, Z.W., Li, C.M., Sun, H.D. J. Nat. Prod. (2002) [Pubmed]
  9. Biotransformation of low-molecular-weight alcohols by Coleus forskohlii hairy root cultures. Li, W., Koike, K., Asada, Y., Yoshikawa, T., Nikaido, T. Carbohydr. Res. (2003) [Pubmed]
  10. Cytochemical localization of phenol-oxidizing enzymes in lignifying Coleus blumei stems. de Pinto, M.C., Ros Barceló, A. European journal of histochemistry : EJH. (1997) [Pubmed]
  11. Molecular cloning and functional expression of geranylgeranyl pyrophosphate synthase from Coleus forskohlii Briq. Engprasert, S., Taura, F., Kawamukai, M., Shoyama, Y. BMC Plant Biol. (2004) [Pubmed]
  12. Production of lepidimoide by an endophytic fungus from polysaccharide extracted from Abelmoschus sp.: identification of the product and the organism producing it. Tanaka, M., Yoshimura, M., Suto, M., Yokota, A., Asano, K., Sukara, E., Tomita, F. J. Biosci. Bioeng. (2002) [Pubmed]
  13. Pharmacology of rosemary (Rosmarinus officinalis Linn.) and its therapeutic potentials. al-Sereiti, M.R., Abu-Amer, K.M., Sen, P. Indian J. Exp. Biol. (1999) [Pubmed]
 
WikiGenes - Universities