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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Hermaphroditism, True

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Disease relevance of Hermaphroditism, True


High impact information on Hermaphroditism, True


Biological context of Hermaphroditism, True


Anatomical context of Hermaphroditism, True

  • OBJECTIVES: Two cases of 46,XX true hermaphroditism were analyzed for two Y-DNA sequences, including the recently cloned gene for male testis determination, the sex-determining region of the Y chromosome (SRY) [14].

Gene context of Hermaphroditism, True


  1. Investigation of the ZFY gene in XX true hermaphroditism and Swyer syndrome. Damiani, D., Billerbeck, A.E., Goldberg, A.C., Setian, N., Fellous, M., Kalil, J. Hum. Genet. (1990) [Pubmed]
  2. Gonadal tumors in disorders of sexual differentiation. Gourlay, W.A., Johnson, H.W., Pantzar, J.T., McGillivray, B., Crawford, R., Nielsen, W.R. Urology (1994) [Pubmed]
  3. Clitoral cyst as a cause of ambiguous genitalia. Linck, D., Hayes, M.F. Obstetrics and gynecology. (2002) [Pubmed]
  4. Aetiological diagnosis of male sex ambiguity: a collaborative study. Morel, Y., Rey, R., Teinturier, C., Nicolino, M., Michel-Calemard, L., Mowszowicz, I., Jaubert, F., Fellous, M., Chaussain, J.L., Chatelain, P., David, M., Nihoul-Fékété, C., Forest, M.G., Josso, N. Eur. J. Pediatr. (2002) [Pubmed]
  5. A reliable endocrine test with human menopausal gonadotropins for diagnosis of true hermaphroditism in early infancy. Mendez, J.P., Schiavon, R., Diaz-Cueto, L., Ruiz, A.I., Canto, P., Söderlund, D., Diaz-Sanchez, V., Ulloa-Aguirre, A. J. Clin. Endocrinol. Metab. (1998) [Pubmed]
  6. SRY gene expression in the ovotestes of XX true hermaphrodites. Ortenberg, J., Oddoux, C., Craver, R., McElreavey, K., Salas-Cortes, L., Guillen-Navarro, E., Ostrer, H., Sarafoglou, K., Clarke, V., Yee, H. J. Urol. (2002) [Pubmed]
  7. The role of the sex-determining region of the Y chromosome (SRY) in the etiology of 46,XX true hermaphroditism. Berkovitz, G.D., Fechner, P.Y., Marcantonio, S.M., Bland, G., Stetten, G., Goodfellow, P.N., Smith, K.D., Migeon, C.J. Hum. Genet. (1992) [Pubmed]
  8. Screening for mutations in the WNT-4 gene in patients with 46,XX true hermaphroditism. Canto, P., Razo, S., Söderlund, D., Calzada-León, R., de la Luz Ruiz-Reyes, M., Ramón, G., Braun-Roth, G., Méndez, J.P. Mol. Genet. Metab. (2004) [Pubmed]
  9. Applicability of the SHBG androgen sensitivity test in the differential diagnosis of 46,XY gonadal dysgenesis, true hermaphroditism, and androgen insensitivity syndrome. Krause, A., Sinnecker, G.H., Hiort, O., Thamm, B., Hoepffner, W. Exp. Clin. Endocrinol. Diabetes (2004) [Pubmed]
  10. Molecular analysis in true hermaphroditism: demonstration of low-level hidden mosaicism for Y-derived sequences in 46,XX cases. Queipo, G., Zenteno, J.C., Peña, R., Nieto, K., Radillo, A., Dorantes, L.M., Eraña, L., Lieberman, E., Söderlund, D., Jiménez, A.L., Ramón, G., Kofman-Alfaro, S. Hum. Genet. (2002) [Pubmed]
  11. Does chromosome 22 have anything to do with sex determination: further studies on a 46,XX,22q11.2 del male. Erickson, R.P., Skinner, S., Jacquet, H., Campion, D., Buckley, P.G., Mantripragada, K.K., Dumanski, J.P. Am. J. Med. Genet. A (2003) [Pubmed]
  12. True hermaphroditism in an XY individual due to a familial point mutation of the SRY gene. Maier, E.M., Leitner, C., Löhrs, U., Kuhnle, U. Journal of pediatric endocrinology & metabolism : JPEM. (2003) [Pubmed]
  13. X-Y translocations and sex differentiation. McElreavey, K., Cortes, L.S. Seminars in reproductive medicine. (2001) [Pubmed]
  14. Detection of the sex-determining region of the Y chromosome in 46,XX true hermaphroditism. Kojima, Y., Hayashi, Y., Asai, N., Maruyama, T., Sasaki, S., Kohri, K. Urologia internationalis. (1998) [Pubmed]
  15. Three patients with 9p deletions including DMRT1 and DMRT2: a girl with XY complement, bilateral ovotestes, and extreme growth retardation, and two XX females with normal pubertal development. Ounap, K., Uibo, O., Zordania, R., Kiho, L., Ilus, T., Oiglane-Shlik, E., Bartsch, O. Am. J. Med. Genet. A (2004) [Pubmed]
  16. Hermaphroditism pathology. Jaubert, F., Nihoul-Fékété, C., Lortat-Jacob, S., Josso, N., Fellous, M. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. (1999) [Pubmed]
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