Disease relevance of Physical Stimulation

• Heparin administration did not seem to be involved, but physical stimulation inside the jugular vein, while not essential, may increase the incidence of tachycardia episodes [1].
• We measured levels of platelet-derived microparticles (PMP), which have coagulative activity and are produced by platelet activation or physical stimulation, and CD62P/CD63-positive platelets in patients with diabetes mellitus to determine their clinical significance and effects on complications of diabetes including diabetic nephropathy [2].

High impact information on Physical Stimulation

• Next, the serum obtained from mice 30 to 60 min after a physical stimulation enhanced PFC of normal mice spleen cells in vitro, but the enhancement was abolished by the addition of propranolol [3].
• Hence neither physical stimulation (cephalic, gastric, or intestinal) nor the luminal presence of glucose, lipids, or bile can induce intestinal response; instead, a combination of nutrients is required (even without pancreaticobiliary secretions), the most important being amino acids and peptides [4].
• NMDA receptor antagonist drugs administered to the hippocampus interfere with long-term potentiation, learning, and memory; these same drugs, when applied to the spinal cord, prevent the long-term neurophysiological changes caused by noxious physical stimulation [5].
• It is suggested that an excess of social and/or physical stimulation in Ts65Dn mice may affect cognition by disturbing the emotional and behavioral components of the learning process [6].
• The ED50 target propofol concentrations for sedation at sedation levels 2 (drowsy), 3 (drowsy, responds to verbal stimulation) and 4 (responsive to physical stimulation only) were 1.0 microg x ml(-1), 1.6 microg x ml(-1) and 2.1 microg x ml(-1), respectively [7].

Anatomical context of Physical Stimulation

• The increase was seen even after the intake of konnyaku (mannan) as a protein-deficient food, suggesting that physical stimulation of the gastric mucosa by food is the main cause of histamine release [8].
• The results suggest that chemical constituents in the diet and physical stimulation of food ingestion, which cause sloughing off of luminal surface tissue, are two major stimuli or epithelial cell proliferation in the new born oesophagus [9].

Associations of Physical Stimulation with chemical compounds

• In conclusion, the present findings suggest that villus morphology is governed neither by intraluminal physical stimulation nor by parenteral alimentation, but by enteral nutrient absorption [10].
• The delayed application of both CaCl2 and NaCl solutions resulted in a tenderizing effect, perhaps by eliminating the toughening effect of the prerigor physical stimulation effect of the earlier injection process [11].
• It is possible that physical stimulation by nicotine may contribute to a more ready arousal to anxiety in smokers [12].
• In the present study the adenosine receptor antagonist could not prevent the ciliostimulative effect of exogenous ATP combined with the physical stimulation [13].
• Massage therapy has been effective with violent adolescents, perhaps because the physical stimulation reduced their dopamine levels and increased their serotonin levels [14].

Gene context of Physical Stimulation

• To evaluate this hypothesis, regional brain cholinergic receptors were compared in rats subjected to 10-day TSD by the disk-over-water method (TSD rats), yoked control (TSC) rats which received the same physical stimulation but with much smaller reductions in sleep, and home cage control (HCC) rats [15].

Analytical, diagnostic and therapeutic context of Physical Stimulation

• After spinal anesthesia was established, sedation was provided with propofol and controlled using a five-point sedation score at 3, "eyes closed but rousable to command", and 4, "eyes closed but rousable to mild physical stimulation". During sedation, blinded anesthesiologist recorded occurrence of complications [16].

References