Disease relevance of Esophageal Diseases

• A population sample selected at random after stratification for the presence of pulmonary disease was screened for benign esophageal disease; 175 subjects agreed to participate in the invasive investigation, 86 without pulmonary disease and 89 with chronic obstructive pulmonary disease (COPD) [1].
• Foscarnet is an effective therapy for CMV disease of the gastrointestinal tract, with rapid resolution of clinical symptoms, long-term remission of esophageal disease, and shorter disease-free periods for CMV colitis [2].
• The benign esophageal diseases included strictures (40%); neuromotor dysfunction-achalasia (24%), esophageal spasm (8%); recurrent gastroesophageal reflux (16%); acute perforation (5%); acute caustic injury (2%); and others (3%) [3].
• Those individuals with typical anginal pain who have normal multistage exercise tests or normal coronary arteriograms and any person with atypical chest pain should be thoroughly evaluated for esophageal disease [4].
• These include trained personnel, use of fluoroscopy, a cooperative patient with a single-, smooth, radiopaque foreign body lodged in the esophagus and a barium esophagogram with negative results for total obstruction and underlying esophageal disease [5].

High impact information on Esophageal Diseases

• This is first antermortem documentation of esophageal disease secondary to WG [6].
• The recent advent of the Bilitec system (Metronics Instruments, Minneapolis, MN), an ambulatory bilirubin monitoring device, is increasing our knowledge of the specific role of DGER in esophageal diseases [7].
• OBJECTIVE: The objective of the study was to prospectively analyze the frequency of severe peptic esophageal disease in ZES patients with and without MEN1 [8].
• This fold pattern can be seen in patients with gastroesophageal reflux and in those with no symptoms of esophageal disease [9].
• Treatment with intravenous penicillin G resulted in symptomatic and histopathological resolution of esophageal disease [10].

Chemical compound and disease context of Esophageal Diseases

• Only three of the 15 patients responding to foscarnet therapy had a relapse of their esophageal disease [2].
• Several factors were shown to be associated with an increased mortality, including delayed treatment, presence of severe underlying esophageal disease, total parenteral nutrition catheter infection, the necessity for major extirpative procedures to treat the perforation, and the use of exclusion and diversion in the continuity procedure [11].

Anatomical context of Esophageal Diseases

• The AIC of the TNM grading of the International Union Against Cancer, the grading of the Japanese Society for Esophageal Diseases, and the grading designed according to the total number of positive lymph nodes became substantially smaller in that order [12].

Gene context of Esophageal Diseases

• S-MK in patients with SESCC (388+/-411 pg/ml) was significantly higher than in benign esophageal disease or healthy controls (183+/-73 and 154+/-76 pg/ml, respectively) [13].
• F-18 FDG uptake in benign esophageal disease [14].
• The median CD4 lymphocyte count at the time of diagnosis of esophageal disease was 12.2 cells/mm3 (range, 3 to 35 cells/mm3) [15].

References