Disease relevance of Esophageal Spasm, Diffuse

• Hydralazine appears to be of value in the treatment of diffuse esophageal spasm and other painful primary esophageal motility disorders [1].
• Changes in the motility tracing with evidence of disordered motility suggestive of diffuse esophageal spasm were seen after bethanechol in seven of the 12 tracings analyzed (58%), including all six patients who developed chest pain [2].
• Other conditions that can mimic asthma include COPD, congestive heart failure, airway obstruction due to various causes, vocal cord dysfunction, and esophageal spasm [3].

High impact information on Esophageal Spasm, Diffuse

• Pentagastrin and diffuse esophageal spasm [4].
• Diffuse esophageal spasm provoked with prostigmine [5].
• But in the group of 5 patients with diffuse esophageal spasm without gastroesophageal reflux, the response was uniformly good [6].
• Esophageal spasm: clinical and manometric response to nitroglycerine and long acting nitrites [6].
• Editorial: symptomatic diffuse esophageal spasm and its relation to gastrin supersensitivity [7].

Chemical compound and disease context of Esophageal Spasm, Diffuse

• The effects of pentagastrin in achalasia and diffuse esophageal spasm [8].
• The patient's chest discomfort and concomitant esophageal spasm were provoked by intravenous infusion of edrophonium chloride during esophageal manometry [9].
• Olfactory stimuli provoke diffuse esophageal spasm: reversal by ipratropium bromide [10].
• This study suggests that verapamil may have potential as a drug therapy in treating the clinical symptoms of achalasia and diffuse esophageal spasm [11].
• CASE SUMMARY: A 24-year-old white woman with a history of esophageal spasms and Raynaud's phenomenon was prescribed nifedipine 10 mg po qid [12].

Biological context of Esophageal Spasm, Diffuse

• Alteration of esophageal peristalsis by pentagastrin in patients with diffuse esophageal spasm [13].

Anatomical context of Esophageal Spasm, Diffuse

• The purpose of this study was to evaluate the effect of intravenous pentagastrin and gastric alkalinization on the lower esophageal sphincter (LES) pressure in seven patients with diffuse esophageal spasm as compared to nine normal controls [14].
• In patients with abnormal tracings, 73 were nonspecific esophageal motility disorder (NEMD), 20 were achalasia, 9 were diffuse esophageal spasm (DES), 8 were nutcracker esophagus, 7 were hypotensive low esophageal sphincter (LES), 3 were abnormal provocative test by edrophonium, and 2 were hypertensive LES [15].

Gene context of Esophageal Spasm, Diffuse

• Possible mechanisms of esophageal spasm and its relief with glucagon are discussed [16].
• The most common esophageal motor abnormalities detected in patients with and without MVP were diffuse esophageal spasm (prevalence, 57%) and non-specific motor disorder (prevalence, 9%), respectively [17].
• A 41-year-old female patient underwent thoracoscopic esophagomyotomy for diffuse esophageal spasm (DOS) with normal resting pressure and complete relaxation of the LOS; findings were confirmed in two preoperative esophageal manometries [18].

Analytical, diagnostic and therapeutic context of Esophageal Spasm, Diffuse

• A case of propranolol overdose complicated by esophageal spasm preventing extrication of an orogastric lavage tube and relieved by intravenous glucagon is presented [16].

References