Disease relevance of Brain Concussion

• The SPD did not differ significantly in brain concussion, or diffuse, focal and combined brain injury groups compared with the control group [1].
• This Xe/CT CBF study in acute stages of cerebral concussion, in which patients were amnestic, detected focal cerebral hyperemia [2].
• The most frequent injuries among patients with epilepsy are contusions, wounds, fractures, abrasions and brain concussions [3].
• Six personal cases of alpha coma are reported: 3 following a cerebrovascular accident and 3 resulting from cerebral concussion [4].
• Immunohistochemical staining for microtubule-associated protein 2 (MAP2) and synaptophysin was used to investigate the effect of hypoxia on hippocampal neurons after mild concussion in the rat [5].

High impact information on Brain Concussion

• Clinically, patients varied from those with mild concussions without focal neurological signs to those with severe neurological dysfunction including posttraumatic coma [6].
• Decreases were 42% for ICD 850, brain concussion, 56% for ICD 800, 801, 803, cranial fractures, and 16% for ICD 851 854, structural brain injury [7].
• Retrospective report on the effectiveness of a polyurethane football helmet cover on the repeated occurrence of cerebral concussions [8].
• The patient in this case report sustained generalized contusions, a cerebral concussion, a midline fracture of the mandibular corpus, and bilateral fractures of the condylar process of the mandible when he fell asleep while driving a car and collided with a truck [9].
• In conclusion it is suggested that the alterations of catecholamine and 5-hydroxytryptamine utilization in discrete brain areas, especially in the striatum are the characteristic feature of disturbances after experimental brain concussion [10].

Chemical compound and disease context of Brain Concussion

• Cerebral concussion in the rat leads within 6 h to an increase in 5-hydroxytryptamine and a decrease in dopamine utilization in the striatum [10].

Anatomical context of Brain Concussion

• The activity of mitochondrial enzymes (succinic dehydrogenase and cytochrome oxidase) and enzymes associated with blood-brain barrier function (butyrylcholinesterase and alkaline phosphatase) in the CNS of rats was studied from 5 minutes to 62 hours after cerebral concussion [11].

Gene context of Brain Concussion

• Computer tomography (CT) and spectrophotometry of CSF were performed in 30 patients with the clinical diagnosis of cerebral concussion or contusion [12].
• PTA proved to be a reliable indicator of the severity of cerebral concussion and correlated with post-concussional sequelae and periods of disability [13].

References