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Chemical Compound Review

Prunasin     (2R)-2-phenyl-2- [(2S,3R,4S,5S,6R)-3,4,5...

Synonyms: D-Prunasin, CPD-553, SureCN377612, AG-L-66450, CHEMBL1778417, ...
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Disease relevance of Prunasin


High impact information on Prunasin


Biological context of Prunasin


Anatomical context of Prunasin


Associations of Prunasin with other chemical compounds

  • 5. The results indicate that prunasin is absorbed unmetabolised in the jejunum of the rat via the transport system of glucose [10].
  • A new acylated triterpene together with prunasin, (-)-epicatechin, daucosterol, and three triterpenes, ursolic, oleanolic, and pomolic acids was isolated from the root of Chaenomeles japonica (THUNB.) LINDL [11].

Analytical, diagnostic and therapeutic context of Prunasin


  1. Amygdalin (Laetrile) and prunasin beta-glucosidases: distribution in germ-free rat and in human tumor tissue. Newmark, J., Brady, R.O., Grimley, P.M., Gal, A.E., Waller, S.G., Thistlethwaite, J.R. Proc. Natl. Acad. Sci. U.S.A. (1981) [Pubmed]
  2. Vicianin, prunasin, and beta-cyanoalanine in common vetch seed as sources of urinary thiocyanate in the rat. Ressler, C., Tatake, J.G. J. Agric. Food Chem. (2001) [Pubmed]
  3. Toxicity of D, L-mandelonitrile-beta-D-glucoside, "prulaurasin" in rat. Sakata, M., Yoshida, A., Yuasa, C., Sakata, K., Haga, M. The Journal of toxicological sciences. (1987) [Pubmed]
  4. Investigation of the microheterogeneity and aglycone specificity-conferring residues of black cherry prunasin hydrolases. Zhou, J., Hartmann, S., Shepherd, B.K., Poulton, J.E. Plant Physiol. (2002) [Pubmed]
  5. Intestinal first pass metabolism of amygdalin in the rat in vitro. Strugala, G.J., Rauws, A.G., Elbers, R. Biochem. Pharmacol. (1986) [Pubmed]
  6. Cyanogenic glycosides from the rare Australian endemic rainforest tree Clerodendrum grayi (Lamiaceae). Miller, R.E., McConville, M.J., Woodrow, I.E. Phytochemistry (2006) [Pubmed]
  7. Chromatographic determination of cyanoglycosides prunasin and amygdalin in plant extracts using a porous graphitic carbon column. Berenguer-Navarro, V., Giner-Galván, R.M., Grané-Teruel, N., Arrazola-Paternina, G. J. Agric. Food Chem. (2002) [Pubmed]
  8. Relationship between cyanogenic compounds in kernels, leaves, and roots of sweet and bitter kernelled almonds. Dicenta, F., Martínez-Gómez, P., Grané, N., Martín, M.L., León, A., Cánovas, J.A., Berenguer, V. J. Agric. Food Chem. (2002) [Pubmed]
  9. The pharmacokinetics of prunasin, a metabolite of amygdalin. Rauws, A.G., Olling, M., Timmerman, A. J. Toxicol. Clin. Toxicol. (1982) [Pubmed]
  10. Small-intestinal transfer mechanism of prunasin, the primary metabolite of the cyanogenic glycoside amygdalin. Strugala, G.J., Stahl, R., Elsenhans, B., Rauws, A.G., Forth, W. Human & experimental toxicology. (1995) [Pubmed]
  11. A new acylated triterpene from the roots of Chaenomeles japonica. Xu, Y.N., Kim, J.S., Kang, S.S., Son, K.H., Kim, H.P., Chang, H.W., Bae, K. Chem. Pharm. Bull. (2002) [Pubmed]
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