Disease relevance of Decamine

• There were no nervous system pathologic changes although the rats were exposed to sufficient amounts of 2,4-D amine to cause severe skin lesions, decreased body weights, and increased kidney weights [1].
• In this second in a series of famous historic personages who suffered from ear disease (see Yardley M, Rutka J. Troy, Mycenae, and the Otologic Demise of Herr Heinrich Schliemann. J Otolaryngol 1998; 27:217-221), we review the life and otology-related death of the legendary playwright Oscar Wilde [2].

High impact information on Decamine

• Seed plant phylogeny: Demise of the anthophyte hypothesis [3]?
• Oxamflatin [(2E)-5-[3-[(phenylsufonyl) aminol phenyl]-pent-2-en-4-ynohydroxamic acid] induces transcriptional activation of junD and morphological reversion in various NIH3T3-derived transformed cell lines [4].
• The hydroxylation of the methyl group at N-3 yields the corresponding aminol, some of which is covalently bonded to a water-soluble compound [5].
• The Premature Demise of Public Child and Adolescent Inpatient Psychiatric Beds : Part II: Challenges and Implications [6].
• A 90-min treatment with 2.0-10.0 microg/ml 2,4-D and 2,4-D DMA produced dose-dependent increases in the frequency of DNA-strand breaks detected in the SCGE assay, both in cultures harvested immediately after treatment and in cultures harvested 36 h later [7].

Biological context of Decamine

• Therefore, we aimed to evaluate the effects of 2,4-D DMA on odontogenesis in rats [8].

Anatomical context of Decamine

• Genotoxicity of the 2,4-dichlorophenoxyacetic acid (2,4-D) and a commercially-used derivative, 2,4-D dimethylamine salt (2,4-D DMA), was evaluated in CHO cells using SCE and single cell gel electrophoresis (SCGE) assays [7].

Associations of Decamine with other chemical compounds

• Nitrile butyl rubber glove permeation of pesticide formulations containing 2,4-D-amine, DDT, DEET, and Diazinon [9].

Analytical, diagnostic and therapeutic context of Decamine

• 65Zn retention was considerably higher in both groups fed low-Zn formula (40%) than in the control group (20%), whereas plasma Zn levels were normal in all infants [10].

References