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Chemical Compound Review

AG-F-68764     2,6,10,14,19,23,27,31- octamethyldotriacont...

Synonyms: CTK4J2327, CTK8I9033, AC1L4V5P, 502-64-7, y,y-Carotene, 7,8-dihydro-
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Disease relevance of C05431

  • Biosynthesis of carotenoids derived from neurosporene in Rhodopseudomonas capsulata [1].
  • Approximately 10% of known phytoene desaturases, as in Rhodobacter, produce neurosporene, whereas the rest produce lycopene [2].
  • In Rb. sphaeroides, the completion of four desaturations to lycopene by the Erwinia CrtI appears to require the absence of CrtC and, in a crtC background, even the native 3-step enzyme can synthesize a significant amount (13%) of lycopene, in addition to the expected neurosporene [3].
  • To test whether Sll0254 serves as a lycopene cyclase in Synechocystis, the corresponding gene was expressed in Escherichia coli strains that can produce lycopene or neurosporene [4].

High impact information on C05431


Chemical compound and disease context of C05431


Biological context of C05431


Associations of C05431 with other chemical compounds


Gene context of C05431


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  2. Alteration of product specificity of Rhodobacter sphaeroides phytoene desaturase by directed evolution. Wang, C.W., Liao, J.C. J. Biol. Chem. (2001) [Pubmed]
  3. Functional assembly of the foreign carotenoid lycopene into the photosynthetic apparatus of Rhodobacter sphaeroides, achieved by replacement of the native 3-step phytoene desaturase with its 4-step counterpart from Erwinia herbicola. Garcia-Asua, G., Cogdell, R.J., Hunter, C.N. Mol. Microbiol. (2002) [Pubmed]
  4. Sll0254 (CrtL(diox)) is a bifunctional lycopene cyclase/dioxygenase in cyanobacteria producing myxoxanthophyll. Mohamed, H.E., Vermaas, W.F. J. Bacteriol. (2006) [Pubmed]
  5. Slr1293 in Synechocystis sp. strain PCC 6803 Is the C-3',4' desaturase (CrtD) involved in myxoxanthophyll biosynthesis. Mohamed, H.E., Vermaas, W. J. Bacteriol. (2004) [Pubmed]
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  9. The resonance Raman spectrum of carotenoids as an intrinsic probe for membrane potential. Oscillatory changes in the spectrum of neurosporene in the chromatophores of Rhodopseudomonas sphaeroides. Koyama, Y., Long, R.A., Martin, W.G., Carey, P.R. Biochim. Biophys. Acta (1979) [Pubmed]
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  11. A novel carotenoid biosynthesis gene coding for zeta-carotene desaturase: functional expression, sequence and phylogenetic origin. Linden, H., Misawa, N., Saito, T., Sandmann, G. Plant Mol. Biol. (1994) [Pubmed]
  12. Inhibition of carotenoid synthesis in Micrococcus roseus. Cooney, J.J., Berry, R.A. Can. J. Microbiol. (1981) [Pubmed]
  13. Investigation of the effects of different carotenoids on the absorption and CD signals of light harvesting 1 complexes. Georgakopoulou, S., van der Zwan, G., Olsen, J.D., Hunter, C.N., Niederman, R.A., van Grondelle, R. The journal of physical chemistry. B, Condensed matter, materials, surfaces, interfaces & biophysical. (2006) [Pubmed]
  14. Functional complementation in Escherichia coli of different phytoene desaturase genes and analysis of accumulated carotenes. Linden, H., Misawa, N., Chamovitz, D., Pecker, I., Hirschberg, J., Sandmann, G. Z. Naturforsch., C, J. Biosci. (1991) [Pubmed]
  15. Early steps in carotenoid biosynthesis: sequences and transcriptional analysis of the crtI and crtB genes of Rhodobacter sphaeroides and overexpression and reactivation of crtI in Escherichia coli and R. sphaeroides. Lang, H.P., Cogdell, R.J., Gardiner, A.T., Hunter, C.N. J. Bacteriol. (1994) [Pubmed]
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