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Chemical Compound Review

LS-64817     (9S,14S)-3,4-dihydroxy-13- methyl-7,8,9,11...

Synonyms: BRN 1999480, AC1L2C0C, 3,4-Dihydroxyestra-1,3,5(10)-trien-17-one, ESTRA-1,3,5(10)-TRIEN-17-ONE, 3,4-DIHYDROXY-
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Disease relevance of BRN 1999480


High impact information on BRN 1999480


Biological context of BRN 1999480


Anatomical context of BRN 1999480


Associations of BRN 1999480 with other chemical compounds


Analytical, diagnostic and therapeutic context of BRN 1999480


  1. Expression of UGT2B7, a UDP-glucuronosyltransferase implicated in the metabolism of 4-hydroxyestrone and all-trans retinoic acid, in normal human breast parenchyma and in invasive and in situ breast cancers. Gestl, S.A., Green, M.D., Shearer, D.A., Frauenhoffer, E., Tephly, T.R., Weisz, J. Am. J. Pathol. (2002) [Pubmed]
  2. A metabolite of equine estrogens, 4-hydroxyequilenin, induces DNA damage and apoptosis in breast cancer cell lines. Chen, Y., Liu, X., Pisha, E., Constantinou, A.I., Hua, Y., Shen, L., van Breemen, R.B., Elguindi, E.C., Blond, S.Y., Zhang, F., Bolton, J.L. Chem. Res. Toxicol. (2000) [Pubmed]
  3. Induction by estrogens of methotrexate resistance in MCF-7 breast cancer cells. Thibodeau, P.A., Bissonnette, N., Bédard, S.K., Hunting, D., Paquette, B. Carcinogenesis (1998) [Pubmed]
  4. Conversion of estrone to 2- and 4-hydroxyestrone by hamster kidney and liver microsomes: implications for the mechanism of estrogen-induced carcinogenesis. Zhu, B.T., Bui, Q.D., Weisz, J., Liehr, J.G. Endocrinology (1994) [Pubmed]
  5. Estrone and estradiol metabolism in vivo in human breast cysts. Raju, U., Sepkovic, D.W., Miller, W.R., Dixon, J.M., Bradlow, H.L., Levitz, M. Steroids (2000) [Pubmed]
  6. Superior and distinct antioxidant effects of selected estrogen metabolites on lipid peroxidation. Tang, M., Abplanalp, W., Ayres, S., Subbiah, M.T. Metab. Clin. Exp. (1996) [Pubmed]
  7. Characterization of rabbit UDP-glucuronosyltransferase UGT1A7: tertiary amine glucuronidation is catalyzed by UGT1A7 and UGT1A4. Bruck, M., Li, Q., Lamb, J.G., Tukey, R.H. Arch. Biochem. Biophys. (1997) [Pubmed]
  8. Metabolism of [4-14C]estrone in hamster and rat hepatic and renal microsomes: species-, sex- and age-specific differences. Haaf, H., Metzler, M., Li, J.J. J. Steroid Biochem. Mol. Biol. (1992) [Pubmed]
  9. In vitro metabolic conjugation of catechol estrogens. Shimada, K., Yumura, Y., Terashima, E., Nambara, T. J. Steroid Biochem. (1984) [Pubmed]
  10. Radioimmunoassay for 4-hydroxyestrone 4-methyl ether in human urine. Emons, G., Klinger, B., Haupt, O., Ball, P. Horm. Metab. Res. (1982) [Pubmed]
  11. In vitro O-methylation of 4-hydroxyestrone monosulfates. Shimada, K., Yumura, Y., Nambara, T. J. Pharmacobio-dyn. (1982) [Pubmed]
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